Otsuka Holdings Co., Ltd.: all 780 studies

Page 5 of 8. Open to participants first (58), then studies with results posted, then the rest; newest registration first within each.

• A Trial to Compare the Amount of Centanafadine That Enters the Bloodstream for Two Different Formulations of CentanafadineCompletedNCT07465731Phase 1
• Herbal Dietary Supplementation on Vasomotor Symptoms in Menopausal WomenCompletedNCT07408115Not applicable
• A Study of a Sleep Supplement to Improve Sleep in Women Going Through MenopauseCompletedNCT07375095Not applicable
• A Brain Imaging Study to Assess the Binding of MSP-2020 to Serotonin 5-HT2A Receptors in Healthy Male AdultsTerminatedNCT07329621Phase 1
• A Trial to Assess How Centanafadine Interacts With Stimulants in the BodyCompletedNCT07314333Phase 1
• A Study to Detect Radioactivity of [14C]-OPC-167832 in Urine and Feces in Healthy MenCompletedNCT07314320Phase 1
• A Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and WomenCompletedNCT07305779Phase 1
• A Trial to Characterize Differences in Blood Levels of Different Lots of Centanafadine QD XR and to Understand the Effect of Food on Blood LevelsCompletedNCT07253441Phase 1
• Phase I Study Multi Dose of 7.5mg Tolvaptan in Health MaleCompletedNCT07166887Phase 1
• a Phase I PK Study in Healthy Male Subjects. 2 Groups of Healthy Male SubjectsCompletedNCT07166796Phase 1
• Single Dose of 7.5mg Tolvaptan Phase I Clinical Trial ProtocolCompletedNCT07166783Phase 1
• Safety and Tolerability, and PK of Sibeprenlimab in Chinese Healthy SubjectCompletedNCT07105124Phase 1
• P3b Short-term Study of CTN in Patients With ADHD and Comorbid AnxietyCompletedNCT06973577Phase 3
• A Study to Evaluate Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Multiple Doses of VIS954CompletedNCT06937593Phase 1
• Impact of Nutritional Supplementation on Sleep QualityCompletedNCT06935123Phase 1
• A Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Participants With Sjögren'sActive, not recruitingNCT06928142Phase 2
• A Trial of the Efficacy and Safety of SEP-363856 in Acutely Psychotic Participants With SchizophreniaActive, not recruitingNCT06894212Phase 3
• A Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of VIS171 in Participants With Autoimmune Disease(s)Active, not recruitingNCT06799520Phase 1
• A Proof-of-concept Trial for OPC 131461 in Patients Hospitalized for Worsening Heart FailureWithdrawnNCT06795399Phase 2
• A Phase 2 Study of JNT-517 in Adolescent Participants With PhenylketonuriaCompletedNCT06637514Phase 2
• Software as a Medical Device for the Treatment of Patients With PTSDActive, not recruitingNCT06589505Phase 2/3
• Futibatinib in Patients Previously Enrolled in an Antecedent Futibatinib as Monotherapy or Combination Therapy.Active, not recruitingNCT06506955Phase 2/3
• A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy SubjectsCompletedNCT06303648Phase 1
• Hot Flash and Night Sweat Virtual StudyActive, not recruitingNCT06289907Not applicable
• An Evaluation of the Long-term Efficacy and Safety of Methylone for the Treatment of PTSDCompletedNCT06237426Phase 2
• An Evaluation of the Safety and Efficacy of Methylone for the Treatment of PTSDCompletedNCT06215261Phase 2
• A Study to Investigate the Safety and Tolerability of CAN10 Antibody in Healthy Subjects and in Subjects With Plaque Psoriasis.CompletedNCT06143371Phase 1
• PK/Efficacy Bridging Study of ASTX727 in Chinese Subjects With Myelodysplastic SyndromesActive, not recruitingNCT06091267Phase 1/2
• Effect of a Nutritional Supplement on Mental Wellness in AdultsCompletedNCT06058364Not applicable
• REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors)Active, not recruitingNCT05973773Phase 3
• Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid TumorsActive, not recruitingNCT05945823Phase 2
• Phase II Clinical Trial of OPS-2071 in the Treatment of Irritable Bowel Syndrome of Diarrhea TypeCompletedNCT05923892Phase 2
• A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic LeukemiaActive, not recruitingNCT05883956Phase 3
• A Clinical Study to Learn if SEP-363856 Has Physical Dependence in Adults With SchizophreniaCompletedNCT05848700Phase 1
• A Study Investigating the Effects of a Novel Mindfulness Approach on Frequency and Duration of Meditation and Self-Reported Stress and Mood in Generally Healthy AdultsCompletedNCT05832645Not applicable
• Refine and Assess the Readability of Patient, Carer, and Clinician Treatment Preference in Myelodysplasia QuestionnaireCompletedNCT05817331
• Herbal Nutraceutical Supplementation on Vasomotor Symptoms in Menopausal WomenCompletedNCT05813067Not applicable
• First-in-Human, Multiple Part Clinical Study of JNT-517 in Healthy Participants and in Participants With PhenylketonuriaCompletedNCT05781399Phase 1/2
• Evaluate the Efficacy and Safety of the Cilostazol-coated BioMimics 3D Stent System in Patients with Peripheral Arterial Occlusive DiseaseActive, not recruitingNCT05759819Not applicable
• A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety DisorderCompletedNCT05729373Phase 2/3
• Samtasu Post-marketing General Drug Use-results Survey in Patients With Volume Overload in Heart Failure.Active, not recruitingNCT05712746
• A Study of TAS3731 in Healthy AdultsCompletedNCT05691660Phase 1
• To Demonstrate the Superiority of IMP (1% OPA-15406 Ointment) to the Vehicle in Adult Patients With ADCompletedNCT05667623Phase 3
• To Demonstrate the Superiority of IMP (0.3% and 1% OPA-15406 Ointment) Versus the Vehicle in Pediatric Patients with ADCompletedNCT05650320Phase 3
• A Mass Balance Study of [14C] TAS-303 in Healthy Adult Male SubjectsCompletedNCT05621447Phase 1
• A Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive DisorderCompletedNCT05593029Phase 2
• OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese SubjectsCompletedNCT05583474Phase 3
• A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With SchizophreniaCompletedNCT05542264Phase 1
• Trial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive DisorderCompletedNCT05536414Phase 2
• Open-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and AnxietyWithdrawnNCT05504486Phase 4
• A Clinical Study That Will Assess the Effect of SEP-363856 and Prior Antipsychotic (PA) Standard of Care on Glucose and Regulation of Insulin in Patients With SchizophreniaCompletedNCT05463770Phase 1
• OPC-61815 in Healthy Chinese Male SubjectsCompletedNCT05439148Phase 1
• A Trial of Centanafadine Efficacy and Safety in Children With Attention-deficit/ Hyperactivity Disorder (ADHD)CompletedNCT05428033Phase 3
• A Study to Evaluate the Safety, PK and PD of VIS171 in Participants (Healthy and With Autoimmune Disease)CompletedNCT05418101Phase 1
• A Study of Tolinapant in Combination With Oral Decitabine/Cedazuridine and Oral Decitabine/Cedazuridine Alone in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma (R/R PTCL)TerminatedNCT05403450Phase 1
• A Clinical Study That Will Assess How Food Moves Through the Stomach and Effects Blood Glucose Levels in Subjects With Schizophrenia Taking SEP-363856 or and Prior Antipsychotic (PA) StandardCompletedNCT05402111Phase 1
• A Phase 2a Study of TAS5315 in Patients With Chronic Spontaneous UrticariaCompletedNCT05335499Phase 2
• A Long-term Administration Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With SchizophreniaCompletedNCT05326347Phase 3
• A Clinical Study of the Paradise™ Renal Denervation System in Patients With Hypertension (RADIANCE-HTN DUO)Active, not recruitingNCT05326230Not applicable
• A Trial of Centanafadine Long-term Safety in Children and Adolescents With Attention-deficit/Hyperactivity Disorder.CompletedNCT05279313Phase 3
• A Trial of Centanafadine Efficacy and Safety in Adolescents With Attention- Deficit/Hyperactivity DisorderCompletedNCT05257265Phase 3
• Trial of Sibeprenlimab in the Treatment of A Nephropathy (IgAN)Active, not recruitingNCT05248646Phase 3
• A Study of Pimitespib in Combination With Imatinib in Patients With GIST (CHAPTER-GIST-101)Active, not recruitingNCT05245968Phase 1
• A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/SertralineTerminatedNCT05189977Phase 1
• A Clinical Pharmacology Trial of Brexpiprazole Long Acting Injectable (LAI) Administered as a Single Dose in Patients With SchizophreniaWithdrawnNCT05119894Phase 1
• RADIANCE Continued Access ProtocolActive, not recruitingNCT05017935Not applicable
• This is a Study to Determine the Effect of Multiple Doses of an Investigational Drug, Taken by Mouth, in People With Narcolepsy-cataplexy. Accepting Both Males and Females Ages of 18 Years to 55 Years. This Study Will be Conducted in the US and Will Require Approximately 13 Weeks Participation.CompletedNCT05015673Phase 1
• A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor CancerTerminatedNCT04982926Phase 1
• Phase 1b/2 Study of Futibatinib in Combination With Binimetinib in Patients With Advanced KRAS Mutant CancerTerminatedNCT04965818Phase 1
• Thorough QT Assessment of Cedazuridine in Healthy SubjectsCompletedNCT04953923Phase 1
• Aripiprazole Once-Monthly in Hospitalized Patients (INITIATE)Status unknownNCT04907279
• A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.CompletedNCT04865835Phase 1
• Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of NO-13065 in Healthy and Obese Adult SubjectsCompletedNCT04838639Phase 1
• Mass Balance Study of [14C] TAS-205 in Healthy VolunteersCompletedNCT04825431Phase 1
• Specified Drug-use Survey on Abilify Prolonged Release Aqueous Suspension for IM Injection (Prevention of Relapse of Mood Episodes in BP)CompletedNCT04812379
• Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADHActive, not recruitingNCT04790175
• A Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine Capsules in Pediatric Subjects With Attention-deficit Hyperactivity DisorderCompletedNCT04786730Phase 1
• A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)WithdrawnNCT04786574Phase 3
• TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN MutationsTerminatedNCT04770246Phase 1
• Clinical Study of an Ultrasound Renal Denervation System in Patients With Heart FailureCompletedNCT04719637Not applicable
• Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)Active, not recruitingNCT04657081Phase 1/2
• Safety and Efficacy Study of OPC-415 in Patients With Relapsed and/or Refractory Multiple MyelomaTerminatedNCT04649073Phase 1/2
• "Brexpiprazole (Rexulti™) Safety and Efficacy Among Filipino Patients (RAISE) - A Post Marketing Surveillance Program"Status unknownNCT04641780
• MIMICS-3D-USA Registry StudyActive, not recruitingNCT04640597
• A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid NeoplasmsTerminatedNCT04637009Phase 1
• A Phase 3 Study of TAS-205 in Patients With Duchenne Muscular Dystrophy（REACH-DMD）CompletedNCT04587908Phase 3
• A Study of TAS0612 in Participants With Advanced or Metastatic Solid Tumor CancerTerminatedNCT04586270Phase 1
• A Nutritional Supplement on Vasomotor Symptoms in WomenCompletedNCT04516304Not applicable
• A Phase 2 Study of TAS-303 in Female Patients With Stress Urinary IncontinenceCompletedNCT04512053Phase 2
• Expanded Access Study of TAS-120 in Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene RearrangementsApproved for marketingNCT04507503
• Effect of Food on the Pharmacokinetics of ASTX660 in Healthy VolunteersCompletedNCT04479800Phase 1
• A Phase 1 Study to Evaluate the Effect of Food on Pharmacokinetics of ASTX029CompletedNCT04466514Phase 1
• A Study to Investigate the Effect of CYP3A4 Inhibition on the Single Dose Pharmacokinetics of ASTX660 and the Effect of a Single Dose of ASTX660 on the Pharmacokinetics of the CYP3A4 Substrate MidazolamCompletedNCT04411030Phase 1
• A Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine in Pediatric Subjects With Attention-deficit/Hyperactivity DisorderCompletedNCT04398225Phase 1
• A Clinical Study to Investigate the Effect of an Investigational Drug on Electrocardiogram Intervals in Adults With Schizophrenia.CompletedNCT04369391Phase 1
• A Study of TAS1440 With ATRA in Subjects With r/r AMLTerminatedNCT04282668Phase 1
• A Single-blind, Placebo-controlled, Outpatient Trial to Assess the Effects of Single Oral Tablet Dose of OPC-214870CompletedNCT04241965Phase 1
• The Study for CML Who Failed Prior TKIs or With T315I Mutation or Ph+ ALL Who Failed Prior TKIs or With T315I MutationCompletedNCT04233346Phase 2
• A Study to Evaluate the Efficacy and Safety of MCT-SR in Patients With GastritisCompletedNCT04189705Phase 3
• A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML)TerminatedNCT04155580Phase 1

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