Novo Nordisk A/S: Overweight trials

The registry lists 121 Overweight studies with Novo Nordisk A/S as lead sponsor. 33 are open to participants now and 23 have results posted.

Phase 1 60Phase 2 7Phase 3 37Phase 4 2No phase 16(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Semaglutide Health Outcomes and Patient Adherence in AustraliaNot yet recruitingNCT07881770
• A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide MedicationRecruitingNCT07868354Phase 1
• A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide MedicationRecruitingNCT07855133Phase 1
• A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body WeightNot yet recruitingNCT07845578Phase 1
• AMAZE 10: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People in Japan With Excess Body Weight Lose WeightRecruitingNCT07822061Phase 3
• A Research Study Looking at the Effect of Timing of Meal After Dosing and Water Volume at Dosing on How the Medicine Zenagamtide is Taken up by the Body of Participants With Overweight or ObesityRecruitingNCT07815067Phase 1
• Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body WeightRecruitingNCT07770841Phase 3
• A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or ObesityRecruitingNCT07767175Phase 1
• A Research Study to See How NNC0487-0111 Affects the Body's Energy Use After a Weight Loss in Adults Living With Overweight or Obesity, Compared to a Low-calorie Diet or PlaceboRecruitingNCT07757087Phase 1
• A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body WeightRecruitingNCT07745504Phase 3
• AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose WeightRecruitingNCT07720271Phase 3
• A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body WeightRecruitingNCT07710768Phase 1
• A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become PregnantRecruitingNCT07710729Phase 1
• A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to SemaglutideRecruitingNCT07668414Phase 3
• AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose WeightNot yet recruitingNCT07668401Phase 3
• Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse EventsRecruitingNCT07607587Phase 1
• A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or ObesityRecruitingNCT07597018Phase 1
• A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in People With Reduced Liver Function and Normal Liver FunctionNot yet recruitingNCT07587710Phase 1
• A Research Study Investigating the Effect of NNC0497-0040 in Healthy Participants, Participants With Overweight or Obesity, and Participants With Type 1 Diabetes With Overweight or ObesityRecruitingNCT07578584Phase 1
• AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaRecruitingNCT07571109Phase 3
• AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaRecruitingNCT07571005Phase 3
• A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or ObesityRecruitingNCT07566390Phase 1
• A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or ObesityRecruitingNCT07557953Phase 1
• AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightRecruitingNCT07533175Phase 3
• AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce PainRecruitingNCT07509307Phase 3
• A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or ObesityRecruitingNCT07437079Phase 1
• A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or ObeseRecruitingNCT07411560Phase 1
• AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightNot yet recruitingNCT07400107Phase 3
• A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or ObesityRecruitingNCT07395687Phase 2
• A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body WeightRecruitingNCT07253285Phase 3
• A Multicentre, Prospective, Single-arm, Non-interventional Regulatory Post-marketing Surveillance (rPMS) Study to Investigate the Safety and Effectiveness of Wegovy® (Semaglutide) in Patients With Obesity and Patients With Overweight in Routine Clinical Practice in KoreaEnrolling by invitationNCT07018544
• A Study to Evaluate Safety of Exposure to Wegovy During PregnancyEnrolling by invitationNCT05872022
• A Study to Evaluate the Safety of Exposure to Wegovy During PregnancyEnrolling by invitationNCT05503927
• A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight RangeCompletedNCT06041217Phase 3Results posted
• Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in People Who Have a Body Weight Above the Healthy RangeCompletedNCT05564117Phase 3Results posted
• Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in East Asian People Who Are Overweight or Living With ObesityCompletedNCT05132088Phase 3Results posted
• Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in People Who Are Overweight or Living With Obesity (OASIS 1)CompletedNCT05035095Phase 3Results posted
• Research Study of How Well Semaglutide Works in People Living With Overweight or Obesity.CompletedNCT04251156Phase 3Results posted
• Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide scCompletedNCT04189848Phase 4Results posted
• A Study Comparing the Injection Site Pain Experience After the Injection of Semaglutide B and Semaglutide D With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and ObesityCompletedNCT04143945Phase 2Results posted
• A Research Study on How Well Semaglutide Works in Adolescents With Overweight or ObesityCompletedNCT04102189Phase 3Results posted
• Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or ObesityCompletedNCT04074161Phase 3Results posted
• A Study Comparing the Injection Site Pain Experience After the Injection of 2 Different Solutions of Semaglutide With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and ObesityCompletedNCT04007107Phase 2Results posted
• A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic SteatohepatitisTerminatedNCT04004325Phase 1/2Results posted
• Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.CompletedNCT03856047Phase 2Results posted
• STEP 6: Research Study Investigating How Well Semaglutide Works in People Living With Overweight or ObesityCompletedNCT03811574Phase 3Results posted
• Two-year Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03693430Phase 3Results posted
• Research Study to Look at How Well Semaglutide is at Lowering Weight When Taken Together With an Intensive Lifestyle ProgramCompletedNCT03611582Phase 3Results posted
• Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or ObesityCompletedNCT03574597Phase 3Results posted
• Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or ObesityCompletedNCT03552757Phase 3Results posted
• Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03548987Phase 3Results posted
• STEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03548935Phase 3Results posted
• Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal InsulinCompletedNCT02963922Phase 3Results posted
• Effect of Liraglutide on Body Weight in Overweight or Obese Subjects With Type 2 Diabetes: SCALE™ - DiabetesCompletedNCT01272232Phase 3Results posted
• Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetesCompletedNCT01272219Phase 3Results posted
• Comparison of the Change in Fat Distribution in Overweight and Obese Subjects With Type 2 Diabetes After Insulin TreatmentCompletedNCT00795600Phase 4Results posted
• Real-World Patient and Physician Experience With Semaglutide Across Six Emerging MarketsCompletedNCT07850765
• Weight Loss in Adults Using Semaglutide (Real-world Study)CompletedNCT07627074
• A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body WeightCompletedNCT07605052Phase 1
• A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body WeightActive, not recruitingNCT07525791Phase 1
• Current Status of Cardiovascular Diseases in Chinese Overweight/ Obesity Population: An Epidemiological Study (COPE）CompletedNCT07358052
• A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightWithdrawnNCT07357766Phase 3
• Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With CagrilintideActive, not recruitingNCT07220759Phase 3
• Weight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideActive, not recruitingNCT07220642Phase 3
• A Research Study on How Well Different Doses of the Medicine NNC0662-0419 Help People Living With Overweight or ObesityActive, not recruitingNCT07184632Phase 2
• A Master Protocol for Semaglutide Effects on Cardiovascular and Obesity-related Outcomes in People With Overweight or Obesity in the Real WorldCompletedNCT07141914
• A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants When Injected Under the Skin.CompletedNCT07121153Phase 1
• A Research Study on How a Dose of NNC0662-0419 Works in Japanese, Chinese and Non-Asian Participants Living With Overweight or ObesityCompletedNCT07101783Phase 1
• Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity in the Real WorldCompletedNCT06874751
• A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants After 10 Days of Oral DosingCompletedNCT06820476Phase 1
• A Study Collecting Remote Data in People With an Overweight Condition or Obesity on a Weight Management ProgramCompletedNCT06805539
• A First-in-human Research Study on How NNC0662-0419 Works in People Living With Overweight or ObesityCompletedNCT06737536Phase 1
• A Study on How NNC0174-1213 Works in People With Overweight or Obesity.CompletedNCT06719011Phase 1
• A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or ObesityActive, not recruitingNCT06577766Phase 1
• A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney FunctionCompletedNCT06559527Phase 1
• A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or ObesityCompletedNCT06478563Phase 1
• A Study of How CagriSema Works on Appetite in People With Excess Body WeightCompletedNCT06267092Phase 1
• Assessing Health-Related Quality of Life and Willingness to Pay for Weight Management in Asia-Pacific by GenderCompletedNCT06260696
• A Research Study to See How a New Medicine (NNC0487-0111) Works in People With Overweight or Obesity When Injected Under the SkinCompletedNCT06064006Phase 2
• A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose WeightCompletedNCT05996848Phase 3
• Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in Chinese Adults Who Are Above a Healthy Weight Range (OASIS 3)CompletedNCT05890976Phase 3
• A Study to Characterize the Prevalence of Overweight and Obesity Among Patients With Established Cardiovascular DiseaseCompletedNCT05873660
• A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose WeightCompletedNCT05813925Phase 3
• A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose WeightCompletedNCT05394519Phase 3
• A Research Study on How NNC0487-0111 Works in People With Overweight or ObesityCompletedNCT05369390Phase 1
• A Research Study of How NNC0174-0833 Behaves in Chinese Volunteers Who Are Normal Weight, Overweight or With ObesityCompletedNCT05254158Phase 1
• A Research Study About Weight Loss and Treatment Patterns With the Use of Saxenda® in Adults in Real-life Settings in SwitzerlandCompletedNCT05153590
• SELECT-LIFE: A Research Study Looking at Long-term Effects of Semaglutide in People Who Took Part in the SELECT Cardiovascular Outcomes TrialCompletedNCT04972721
• A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or ObesityCompletedNCT04940078Phase 1
• First Research Study to Look at How Two Medicines, NNC0480-0389 and Semaglutide, Work Together in Healthy People, in People With High Body Weight and in People With DiabetesCompletedNCT04259801Phase 1
• A Research Study to Compare Two Different Forms of Once-weekly Semaglutide in Two Different Injection PensCompletedNCT04238962Phase 1
• A Research Study Looking at the Comparability (Bioequivalence) of Two Versions of SemaglutideCompletedNCT04228354Phase 1
• A Research Study Looking Into Blood Levels of NNC0174-0833 in People With Normal and Impaired Kidney FunctionCompletedNCT04209049Phase 1
• A Research Study Looking at the Comparability (Bioequivalence) of Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or ObesityCompletedNCT04187300Phase 1
• Research Study to Investigate the Effect of NNC0174-0833 on a Birth Control Pill in Women Who Are Not Able to Become PregnantCompletedNCT04074174Phase 1
• Research Study to Investigate How a Study Medicine (NNC9204- 1177) Affects Blood Levels of Other Medicines in Healthy PeopleCompletedNCT04059367Phase 1
• A Research Study to Compare Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or ObesityTerminatedNCT04012255Phase 1
• A Research Study Investigating NNC0247-0829 for Weight Management in People With Overweight or ObesityCompletedNCT04010786Phase 1
• A Research Study to Look at How Semaglutide Affects Gastric Emptying in People With ObesityCompletedNCT03842202Phase 1
• A Research Study of How NNC0174-0833 Behaves in Japanese and Caucasian Volunteers Who Are Normal Weight, Overweight or With ObesityCompletedNCT03787225Phase 1