Norgine: all 62 studies
Page 1 of 1. Open to participants first (2), then studies with results posted, then the rest; newest registration first within each.
- A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for ColonoscopyRecruitingNCT07218523Phase 3
- Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children With Sickle Cell DiseaseRecruitingNCT06578507Phase 2
- A Bioequivalence Study to Compare the Pharmacokinetics of Two Formulations of Hydroxycarbamide in Healthy VolunteersCompletedNCT05025072Phase 1Results posted
- SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial)CompletedNCT03806452Phase 2Results posted
- A Pharmacokinetic Study of PLENVU® in Healthy SubjectsCompletedNCT03437265Phase 1Results posted
- Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH)CompletedNCT02522104Phase 4Results posted
- European Sickle Cell Disease Cohort - HydroxyureaCompletedNCT02516579Results posted
- Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus MOVIPREP® Using 2-Day Split-Dosing and 1-Day Morning Split-Dosing Regimen in Adults.CompletedNCT02273167Phase 3Results posted
- Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus a Sodium Picosulfate and Magnesium Salt Solution Using Day Before-Only Dosing Regimen in Adults.CompletedNCT02273141Phase 3Results posted
- Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus Trisulfate Solution Using 2-Day Split-Dosing Regimen in AdultsCompletedNCT02254486Phase 3Results posted
- Phase III Study Comparing Zegerid® With Losec® for the Relief of Heartburn Associated With Gastroesophageal Reflux DiseaseCompletedNCT01493089Phase 3Results posted
- A Monocentric Study to Investigate a New Low Dose Oral Gut Cleansing SolutionCompletedNCT06597903Phase 2
- The Safety and Dose Response to Single Anal Doses of NRL001CompletedNCT06593743Phase 1
- Safety and Tolerability of the Twice Daily Intra-anal Application of NRL001 Cream for 14 DaysCompletedNCT06593730Phase 1
- Acceptability of a New Paediatric Formulation of Hydroxycarbamide in Children With Sickle Cell Disease.CompletedNCT05470270Phase 2
- Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in IberiaCompletedNCT05174845
- ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension StudyActive, not recruitingNCT04707235
- Plasma DNA and Vascular Remodelling in Patients With Sickle Cell DiseaseCompletedNCT02721472Not applicable
- Real World Outcomes Study of Hepatic Encephalopathy Patients' Experience on Rifaximin (PROSPER)CompletedNCT02488993
- Performance of NER1008 Enema Compared With Fleet® Enema in Bowel CleansingCompletedNCT02468726Not applicable
- Pharmacodynamic Evaluation of Stool Output Following Oral Administration of Various Low Volume PEG3350-based Gut Cleansing Solutions Using the Split Dose Intake in Healthy SubjectsCompletedNCT01834742Phase 1
- A Clinical Investigation to Demonstrate the Performance of a New Enema (TF037) in Distal Bowel Cleansing Compared With Fleet EnemaCompletedNCT01715272Phase 1
- Pharmacodynamic and Clinical Evaluation of Dose and Taste-optimised Low Volume PEG-based Bowel Cleansing Solutions Using the Split-dosing Intake Regimen in Healthy Subjects and in Subjects Undergoing Screening ColonoscopyCompletedNCT01714466Phase 2
- A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting ConditionsCompletedNCT01710995Phase 1
- Study to Evaluate the Safety of Post-Operative TZP-101 (IV Ulimorelin) After Partial Bowel ResectionCompletedNCT01710982Phase 3
- A Multi-centre Study Comparing the Polyp Detection Rate of Two Different Types of Bowel Preparation: a 2-litre Solution (MOVIPREP®) Versus a Hyperosmotic and Stimulant Combined Low Volume Bowel Preparation (Sodium Picosulfate and Magnesium Citrate)CompletedNCT01689792Phase 4
- A Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery and Pharmacokinetics of 14C TZP-101CompletedNCT01668199Phase 1
- A Multi-centre, Phase II, Double-blind, Randomised, Placebo-controlled, Parallel Group, Dose-ranging Study in Patients With Faecal Incontinence; to Evaluate the Efficacy, Safety and Tolerability of Locally Applied NRL001 Over an 8 Week Treatment PeriodCompletedNCT01656720Phase 2
- Evaluation of the Main Determinants of Patient Acceptability of the Bowel Cleansing Procedure, and of Success of Bowel Cleansing and Caecal IntubationCompletedNCT01626196
- Safety and Tolerability of a Single Intra-anal Dose of NRL001 in Healthy VolunteersCompletedNCT01406925Phase 1
- Study to Examine the Effect of Ulimorelin on the Pharmacokinetics of Midazolam in Healthy VolunteersCompletedNCT01405612Phase 1
- Evaluation of the Pharmacokinetics of Ulimorelin in Subjects With Hepatic Impairment and Healthy SubjectsCompletedNCT01405599Phase 1
- Comparator Study of PEG 3350 Versus Prucalopride in Females With Chronic ConstipationCompletedNCT01251822Phase 3
- Study to Assess the Tolerability, Safety and Efficacy of an Adapted Gut Cleansing Solution in Routine Colon Cleansing Prior to ColonoscopiesCompletedNCT01251237Phase 2
- Effect of 7 Days of Dosing With a 10 mg Rectal Suppository of NRL001in Patients With Faecal IncontinenceCompletedNCT01175941Phase 1
- Sensitivity of Alternative NRL972 Detection Methods in Healthy SubjectsCompletedNCT01164332Phase 1
- Safety, Tolerability, Pharmacodynamic and Pharmacokinetics of a Single Rectal Application of 10 mg NRL001 in Elderly SubjectsCompletedNCT01099683Phase 1
- Safety, Tolerability, Pharmacodynamic and Pharmacokinetics of 7.5, 10, 12.5 or 15 mg NRL001 in a 2 g Suppository for 14 DaysCompletedNCT01099670Phase 1
- Effect of Chronic Viral Hepatitis on the Pharmacokinetics of NRL972.CompletedNCT00915057Phase 2
- Reproducibility of Child-Turcotte-Pugh (CTP) Rating and NRL972 Pharmacokinetics in Patients With CirrhosisCompletedNCT00896597Phase 1
- Scintigraphic Assessment Following Klean-Prep® or Moviprep®CompletedNCT00896246Phase 1
- Effect of Single Doses of 10 mg NRL001 Applied as a Suppository to the Anal Canal or RectumCompletedNCT00893607Phase 1
- Effects of Oral PEG 3350 on Electrolyte BalanceCompletedNCT00868985Phase 1
- Evaluation of the PK of NRL972 Following Pre- and co-Administration of Ursodeoxycholic Acid and CloxacillinCompletedNCT00857480Phase 1
- Study to Investigate Safety and Response to 1 or 2 g Rectal Suppositories Containing 5 or 10 mg NRL001.CompletedNCT00857467Phase 1
- Clearance of NRL972 in Patients With Cirrhosis, Nonalcoholic Steatohepatitis (NASH) and in Healthy VolunteersCompletedNCT00856869Phase 1/2
- Evaluation of the Pharmacokinetics of NRL972 Following Pre-Administration of Rifampicin and CyclosporineCompletedNCT00856752Phase 1
- Clearance of NRL972 in Patients With Cirrhosis and in Healthy VolunteersCompletedNCT00856713Phase 1
- Study of Escalating Doses of NRL001 Given in Slow-release Rectal Suppositories of Different WeightsCompletedNCT00850590Phase 1
- Constipation Associated With Irritable Bowel Syndrome (IBS-C)CompletedNCT00796354Phase 3
- PK of NRL972 in Patients with Nonalcoholic Steatohepatitis (NASH) and Non-Alcoholic Fatty Liver Disease (NAFLD)CompletedNCT00794716Phase 2
- Multi-national Cirrhosis Study to Characterise the Association Between the Pharmacokinetics of NRL972 and Disease Severity.CompletedNCT00794482Phase 3
- A Phase IV Study, of the Efficacy, Safety, and Acceptability of Moviprep® Versus Colopeg® in Colonoscopy PreparationCompletedNCT00605228Phase 4
- Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor ScreeningCompletedNCT00427089Phase 3
- Movicol in Childhood Constipation (ProMotion Study)CompletedNCT00404040Phase 2
- An Open Single Centre Study To Assess Treatment of Chronic Constipation in ChildrenCompletedNCT00403897Phase 3
- Movicol in Childhood Constipation (ProMotion Study)CompletedNCT00403858Phase 2
- Study to Examine the Efficacy and Safety of Movicol in the Treatment of Chronic Constipation in ChildrenCompletedNCT00403819Phase 3
- A Phase III Trial to Assess the Efficacy, Acceptability and Safety of Moviprep® Versus a 4L PEG+E Standard SolutionCompletedNCT00389233Phase 3
- MOVIPREP® Versus NaP Pivotal Phase III StudyCompletedNCT00322062Phase 3
- Clinical Evaluation of a New Reduced Volume Bowel PreparationCompletedNCT00321230Phase 2
- MOVIPREP® Versus PICOLAX® Pilot StudyCompletedNCT00312481Phase 2