National Institutes of Health: Uveitis trials

The registry lists 42 Uveitis studies with National Institutes of Health as lead sponsor. 0 are open to participants now and 7 have results posted.

Phase 1 13Phase 2 15Phase 3 2No phase 17(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis (STAR Study)CompletedNCT02911116Phase 2Results posted
• Topical Interferon Gamma for Macular Edema Secondary to UveitisCompletedNCT01376362Phase 1/2Results posted
• Treatment of Non-infectious Intermediate and Posterior Uveitis Associated Macular Edema With Intravitreal MethotrexateTerminatedNCT01314417Phase 1/2Results posted
• Optiquel® as Corticosteroid-sparing Therapy for Chronic Noninfectious UveitisCompletedNCT01195948Phase 1/2Results posted
• Microplasmin Intravitreal Administration in Participants With Uveitic Macular EdemaTerminatedNCT01194674Phase 1/2Results posted
• Efalizumab to Treat UveitisCompletedNCT00280826Phase 1Results posted
• Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated UveitisCompletedNCT00130637Phase 2Results posted
• Microbiome as a ThErapeutic Response BiomarkerWithdrawnNCT04721743
• Biomarkers in Ocular Inflammation and UveitisCompletedNCT04690829
• Uveitis/Intraocular Inflammatory Disease Biobank (iBank)CompletedNCT02656381
• Intestinal Bacteria and Ocular Inflammatory DiseaseCompletedNCT01859299
• Ustekinumab for Active Sight-Threatening UveitisWithdrawnNCT01647152Phase 1/2
• Immunogenetic Mechanisms in Behcet's DiseaseTerminatedNCT01109433
• The Treatment of Uveitic Cystoid Macular Edema With Topical Interferon GammaCompletedNCT00943982Phase 1
• Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior UveitiCompletedNCT00876434Phase 1
• Genetics and Markers of Degenerative and Inflammatory Eye DiseasesCompletedNCT00647439
• Human Samples and Data RepositoryTerminatedNCT00539370
• Eye and Immunogenetic Features of SarcoidosisCompletedNCT00379275
• Differences in Genes and Proteins in Active and Controlled UveitisCompletedNCT00357266
• The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory DiseaseCompletedNCT00331331
• Combination Daclizumab/Denileukin Diftitox to Treat UveitisCompletedNCT00326508Phase 2
• Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort StudyCompletedNCT00116090
• Immune Indicators of UveitisCompletedNCT00089739
• Daclizumab and Sirolimus to Treat UveitisCompletedNCT00078689Phase 1
• Daclizumab to Treat Non-Infectious Sight-Threatening UveitisCompletedNCT00070759Phase 2
• Daclizumab Injections to Treat Non-Infectious Sight-Threatening UveitisCompletedNCT00043667Phase 2
• Vitamin E to Treat Uveitis-Associated Macular EdemaCompletedNCT00021645Phase 1
• The Safety and Efficacy of a Tumor Necrosis Factor Receptor Fusion Protein on Uveitis Associated With Juvenile Rheumatoid ArthritisStatus unknownNCT00012506Phase 3
• Effect of Pregnancy on UveitisCompletedNCT00001867
• HAT in Eye Complications of Behcet's DiseaseCompletedNCT00001865Phase 2
• Leflunomide to Treat UveitisCompletedNCT00001863Phase 2
• TNRF:Fc to Treat Eye Inflammation in Juvenile Rheumatoid ArthritisCompletedNCT00001862Phase 2
• Vascular Endothelial Growth Factor (VEGF) in UveitisCompletedNCT00001738
• Cyclosporin Implant to Treat UveitisCompletedNCT00001737Phase 1
• Screening for NEI Clinical StudiesCompletedNCT00001734
• The Safety and Efficacy of Chicken Type II Collagen on Uveitis Associated With Juvenile Rheumatoid ArthritisCompletedNCT00001614Phase 1
• ANTI-TAC THERAPY FOR UVEITISCompletedNCT00001526Phase 1
• Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis PatientsCompletedNCT00001311Phase 2
• Tissue Studies of Human Eye DiseasesTerminatedNCT00001310
• Analysis of Eye TissueCompletedNCT00001224
• Collaborative Ocular Melanoma Study (COMS)Status unknownNCT00000124Phase 3
• Safety and Efficacy of a Heparin-Coated Intraocular Lens in UveitisStatus unknownNCT00000119Phase 2