National Institutes of Health: Sjogren's Syndrome trials

The registry lists 22 Sjogren's Syndrome studies with National Institutes of Health as lead sponsor. 5 are open to participants now and 4 have results posted.

Phase 1 4Phase 2 9No phase 10(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Pain Phenotyping of Rheumatic Diseases - An Observational StudyNot yet recruitingNCT07829497
• Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren DiseaseRecruitingNCT07281456Phase 2
• Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVORecruitingNCT03816345Phase 1
• Characterization of Diseases With Salivary Gland InvolvementRecruitingNCT02327884
• The Pathogenesis and Natural History of Sjogren's DiseaseRecruitingNCT01425892
• Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's SyndromeActive, not recruitingNCT04496960Phase 1/2Results posted
• Baminercept, a Lymphotoxin-Beta Receptor Fusion Protein, for Treatment of Sjögren's SyndromeTerminatedNCT01552681Phase 2Results posted
• Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome SubjectsTerminatedNCT01316770Phase 2Results posted
• Pilot Study of Raptiva to Treat Sjogren's SyndromeTerminatedNCT00344448Phase 2Results posted
• Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Volunteers Evaluating Oral Health Disparities as Determinants of Oral Health in a High-Risk PopulationCompletedNCT03327870
• Omalizumab for LupusCompletedNCT01716312Phase 1
• Evaluation of the Role of the Autonomic Nervous System in Sj(SqrRoot)(Delta)Gren s SyndromeCompletedNCT00565526
• Anti-CD20 Antibody Therapy for Sjogren's SyndromeCompletedNCT00101829Phase 1
• Study of Oral Bacteria in Patients With Dry MouthCompletedNCT00048685
• Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek CellsCompletedNCT00023491
• Etanercept Therapy for Sjogren's SyndromeCompletedNCT00001954Phase 2
• The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy VolunteersCompletedNCT00001953
• Natural History of Salivary Gland Dysfunction and Sjogren's SyndromeCompletedNCT00001852
• Treatment of Dry Eye Syndrome With Cyclosporin A Eye DropsCompletedNCT00001731Phase 2
• Pilot Study of Thalidomide to Treat Sjogren's SyndromeCompletedNCT00001599Phase 2
• DHEA Treatment for Sjogren's SyndromeCompletedNCT00001598Phase 2
• Evaluation of Salivary Gland DysfunctionTerminatedNCT00001196