National Institutes of Health: Opportunistic Infections trials

The registry lists 14 Opportunistic Infections studies with National Institutes of Health as lead sponsor. 5 are open to participants now and 1 have results posted.

Phase 1 1Phase 2 5Phase 4 1No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 LymphopeniaRecruitingNCT05600920Phase 1/2
• Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ImmunityRecruitingNCT04339777Phase 2
• Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesRecruitingNCT02579967Phase 2
• Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaRecruitingNCT00867269
• Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV InfectionRecruitingNCT00789009
• Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationActive, not recruitingNCT03663933Phase 2Results posted
• Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell LymphomaActive, not recruitingNCT03922724Phase 2
• Mycobacterial and Opportunistic Infections in HIV-Negative Thai and Taiwanese Patients Associated With Autoantibodies to Interferon-gammaActive, not recruitingNCT00814827
• Evaluation and Monitoring of Patients With HIV InfectionnCompletedNCT00557570
• When to Start Anti-HIV Drugs in Patients With Opportunistic InfectionsCompletedNCT00055120Phase 4
• A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) InfectionCompletedNCT00005572
• Monitoring Patients for Developing Communicable and Opportunistic Infections and for Responding to TherapyCompletedNCT00001477
• A Study on the Rate of Opportunistic (AIDS-Related) Infections Among HIV-Positive Children Who Have Stopped Taking Their OI Preventive MedicationsCompletedNCT00001078Not applicable
• A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV InfectionCompletedNCT00000895Not applicable