National Institutes of Health: Nervous System Diseases trials

The registry lists 47 Nervous System Diseases studies with National Institutes of Health as lead sponsor. 5 are open to participants now and 3 have results posted.

Phase 1 7Phase 2 7No phase 37(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and PathologyRecruitingNCT06203626
• Detection and Characterization of Neurologic Manifestations of Inborn and Acquired Errors of ImmunityRecruitingNCT06169150
• Top-Down Attentional Control of Visual-ProcessingRecruitingNCT01087281
• The Neurodevelopmental and Behavioral Phenotyping Screening ProtocolRecruitingNCT00271622
• Evaluation and Treatment of Neurosurgical DisordersRecruitingNCT00060541
• Combined Intrathecal and Intravenous VTS-270 Therapy for Liver and Neurological Disease Associated With Niemann-Pick Disease, Type C1TerminatedNCT03887533Phase 1/2Results posted
• PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright SyndromeCompletedNCT02743377Phase 1/2Results posted
• Augmenting Effects of L-DOPS With Carbidopa and EntacaponeTerminatedNCT00547911Phase 1/2Results posted
• Chart Review: Central Motor Conduction Time in Neurological DisordersCompletedNCT03300856
• Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)WithdrawnNCT03109301Phase 2
• Anakinra, A Recombinant Human IL-1 Receptor Antagonist for Neuroinflammation in HIV-1 InfectionTerminatedNCT02527460Phase 1
• Natural History of Multiple Sclerosis and Its MimickersCompletedNCT02504840
• Cerebrospinal Fluid Collection and Repository StorageTerminatedNCT01862107
• Studying Childhood-onset Behavioral, Psychiatric, and Developmental DisordersCompletedNCT01778504
• Studying Motor Neuron TestsCompletedNCT01517087
• Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II PatientsCompletedNCT01222728
• Connectivity Analysis for Investigation of Auditory Impairment in EpilepsyTerminatedNCT01212068
• Association Between Focal Dystonia and Complex Regional Pain SyndromeCompletedNCT00595439
• Influence of Area of Brain Damage on Brain Reorganization After Chronic StrokeCompletedNCT00474292
• Determining the Prevalence of HIV-Related Neurological Disorders in the Asia PacificStatus unknownNCT00168246
• Central Nervous System Disease in HIV-infected Children on HAARTCompletedNCT00110331
• Evaluation of Primary Chronic Autonomic FailureTerminatedNCT00059033
• Acetyl-L-Carnitine for the Treatment of NRTI-Associated Peripheral NeuropathyCompletedNCT00050271Not applicable
• Test of A Model of Representational Knowledge Stored in the Human Prefrontal CortexCompletedNCT00024908
• PET Scanning in Parkinson s DiseaseCompletedNCT00024622
• Nerve Damage in Patients With HIV Infection Who Have Been Treated With Anti-HIV DrugsCompletedNCT00017771
• Oregon Center for Complementary and Alternative Medicine in Neurological DisordersCompletedNCT00010881Not applicable
• Brain Processing of Language MeaningsCompletedNCT00005004
• Phase I/II Study of Human Anti-Cytomegalovirus (CMV) Monoclonal Antibody MSL-109 in Newborns With Symptomatic Congenital CMV Infection Without Central Nervous System DiseaseCompletedNCT00004642Phase 1/2
• Genotype/Phenotype Correlation of Movement Disorders and Other Neurological DiseasesCompletedNCT00001667
• Sleep Disorders of Patients With Diseases of the Nervous SystemCompletedNCT00001664
• Treatment of Cortical Myoclonus With Repetitive Transcranial Magnetic StimulationCompletedNCT00001663Phase 1
• Functional and Metabolic Imaging Using Magnetic Resonance Imaging and SpectroscopyCompletedNCT00001591
• PET Scan in Patients With Neurocardiologic DisordersCompletedNCT00001418
• Diagnosis and History Study of Patients With Different Neurological ConditionsCompletedNCT00001367
• Magnetic Resonance Imaging for the Study of Patients With Neurological DisordersCompletedNCT00001362
• Magnetic Resonance Imaging Studies of Motor and Thought ProcessesCompletedNCT00001361
• Study of Norepinephrine Levels and Sympathetic Nervous System ActivityCompletedNCT00001329
• Positron Emission Tomography to Measure Pain and Pain ControlCompletedNCT00001307
• Genetic Studies in Alzheimer's DiseaseCompletedNCT00001235
• Non-Invasive Electrical Stimulation of the Human BrainCompletedNCT00001216
• Evaluation of Neuromuscular DiseaseCompletedNCT00001201
• Blood Sampling for Neurochemical and Genetic TestingCompletedNCT00001147
• A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease.WithdrawnNCT00000856Phase 1
• A Phase II, Double-Blind Trial of Recombinant Human Nerve Growth Factor for Treatment of HIV-Associated Sensory NeuropathyCompletedNCT00000842Phase 2
• The Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared With Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected PatientsCompletedNCT00000817Not applicable
• A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV InfectionCompletedNCT00000793Phase 2