National Institutes of Health: Immune System Diseases trials

The registry lists 22 Immune System Diseases studies with National Institutes of Health as lead sponsor. 9 are open to participants now and 4 have results posted.

Phase 1 2Phase 2 6Phase 3 1Phase 4 1No phase 13(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Detection and Characterization of Neurologic Manifestations of Inborn and Acquired Errors of ImmunityRecruitingNCT06169150
• Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ImmunityRecruitingNCT04339777Phase 2
• Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesRecruitingNCT02579967Phase 2
• Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)RecruitingNCT01568697
• Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous SystemRecruitingNCT00794352
• Detection and Characterization of Infections and Infection SusceptibilityRecruitingNCT00404560
• Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)RecruitingNCT00006150
• Genetic Analysis of Immune DisordersRecruitingNCT00001467
• Activation and Function of Eosinophils in Conditions With Blood or Tissue EosinophiliaRecruitingNCT00001406
• A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult ParticipantsActive, not recruitingNCT05217641Phase 1Results posted
• Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationActive, not recruitingNCT03663933Phase 2Results posted
• Anakinra for Behcet s DiseaseCompletedNCT01441076Phase 1/2Results posted
• Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302)CompletedNCT00224874Phase 2Results posted
• Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell LymphomaActive, not recruitingNCT03922724Phase 2
• Feasibility of Measuring Immune Resp, Activation in Foreskin/Mucosa in HIV-, Uncircumcised High-HIV-risk MSM, Lima PeruCompletedNCT02630082Not applicable
• NIAID Clinical Center Genomics Opportunity ProtocolCompletedNCT02417766
• Gulf Long-Term Follow-Up StudyActive, not recruitingNCT01287000
• Screening Protocol for Subjects Being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) ProtocolsCompletedNCT00968084
• Developing Newborn Screening for Infants With Primary ImmunodeficiencyCompletedNCT00113464
• Antibody Production in Immune DisordersTerminatedNCT00023504Phase 4
• Consequences of Conjugal Bereavement in AdultsCompletedNCT00001659
• T-Cell Depletion in Unrelated Donor Marrow TransplantationCompletedNCT00000591Phase 3