National Institutes of Health: Hypertension, Pulmonary trials

The registry lists 22 Hypertension, Pulmonary studies with National Institutes of Health as lead sponsor. 3 are open to participants now and 1 have results posted.

Early Phase 1 1Phase 1 6Phase 2 4Phase 4 1No phase 11(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Pulmonary Hypertension (PH) Biorepository for Translational ResearchRecruitingNCT07647549
• Natural History Study of Biomarkers in Pulmonary Arterial HypertensionRecruitingNCT01730092
• Natural History of Sickle Cell DiseaseRecruitingNCT00081523
• Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell DiseaseTerminatedNCT00492531Phase 2Results posted
• Phosphodiesterase Type-5 Inhibitor Therapy in Sickle Cell People With Pulmonary HypertensionCompletedNCT03572036
• Hydroxyurea in Pulmonary Arterial HypertensionWithdrawnNCT01950585Early Phase 1
• Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell DiseaseWithdrawnNCT01568645Phase 1
• Real-time MRI Right Heart Catheterization Using Passive CathetersCompletedNCT01287026Phase 1/2
• Aerobic Exercise in Patients With Pulmonary HypertensionCompletedNCT00678821Phase 2
• Role of Nitric Oxide in MalariaCompletedNCT00527163
• Pulmonary Hypertension, Hypoxia and Sickle Cell DiseaseCompletedNCT00495638
• Pulmonary Hypertension in Patients With Sickle Cell Disease in NigeriaCompletedNCT00367523
• Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary HypertensionCompletedNCT00352482Phase 2
• Cardiopulmonary Function Assessment and NO-Based Therapies for Patients With Hemolysis-Associated Pulmonary HypertensionCompletedNCT00352430Phase 1
• Sildenafil to Treat HIV-Associated Pulmonary HypertensionTerminatedNCT00327080Phase 1
• Hydroxyurea and Erythropoietin to Treat Sickle Cell AnemiaCompletedNCT00270478Phase 1
• Heart Disease in Sickle Cell AnemiaCompletedNCT00113152
• Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary HypertensionCompletedNCT00023296Phase 1
• Secondary Pulmonary Hypertension in Adults With Sickle Cell AnemiaCompletedNCT00011648
• Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden DeathCompletedNCT00004805Not applicable
• Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary HypertensionCompletedNCT00004754Phase 4
• Evaluation of Patients With Known or Suspected Heart DiseaseCompletedNCT00001313