National Institutes of Health: Hypercholesterolemia trials

The registry lists 44 Hypercholesterolemia studies with National Institutes of Health as lead sponsor. 1 are open to participants now and 3 have results posted.

Phase 1 4Phase 2 9Phase 3 8Phase 4 1No phase 24(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Causes and Natural History of DyslipidemiasRecruitingNCT00353782
• Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque RegressionCompletedNCT01212900Phase 4Results posted
• The Effects of Metformin on Blood Vessel Structure and FunctionCompletedNCT00105066Phase 2Results posted
• Action to Control Cardiovascular Risk in Diabetes (ACCORD)CompletedNCT00000620Phase 3Results posted
• Guideline Adherence for Heart HealthCompletedNCT00224848Phase 2
• Effect of Tenofovir Disoproxil Fumarate on Lipid Levels in HIV Infected Adults on Stable Anti-HIV Drug TherapyCompletedNCT00109603Not applicable
• Evaluating "Health at Every Size"(HAES) as an Alternative Obesity Treatment ModelCompletedNCT00074633Not applicable
• Antioxidant Functions of Lipoic AcidCompletedNCT00065624Phase 2
• Comparing Effects of 3 Sources of Garlic on Cholesterol LevelsCompletedNCT00056511Phase 2/3
• Safety and Effectiveness of Flaxseed for Reducing High CholesterolCompletedNCT00051415Phase 2/3
• Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected PatientsCompletedNCT00046267Not applicable
• Postprandial Lipemia and Endothelial Function in ACCORD- Ancillary to ACCORDCompletedNCT00037401
• Garlic in Hyperlipidemia Caused by HAARTWithdrawnNCT00029250Phase 2
• Effects of Rosiglitazone on Blood Vessels in Patients With High Blood Pressure and High CholesterolCompletedNCT00006071
• Evaluation of Cholesterol Education for At-Risk ChildrenCompletedNCT00005718
• Worksites, Occupational Nurses and Cholesterol ChangeCompletedNCT00005694
• Primary Prevention of CHD Risk Factors Occurring in USCompletedNCT00005495
• Precursors of CVD Risk Factors--Project HeartbeatCompletedNCT00005478
• Lipid Variability--Influence of StressCompletedNCT00005468
• Population-Based Modeling of Cholesterol Lowering in the United StatesCompletedNCT00005463
• Evaluation of Childhood Blood Pressure and Lipid ScreeningCompletedNCT00005439
• Diet and Plasma Cholesterol - Secular Trend AnalysisCompletedNCT00005257
• Sex Steroids, Obesity and Lipids in Adolescent FemalesCompletedNCT00005210
• Hyperapo B and Coronary Heart DiseaseCompletedNCT00005168
• Pawtucket Heart Health ProgramCompletedNCT00005151
• Strong Heart StudyCompletedNCT00005134
• Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial HypercholesterolemiaCompletedNCT00004809Phase 1
• The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3AStatus unknownNCT00004564Not applicable
• Genetic Study of SitosterolemiaCompletedNCT00004481
• Vascular Effects of Endothelium-Derived Versus Hemoglobin-Transported Nitric Oxide in Healthy SubjectsCompletedNCT00001963Phase 1
• Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal WomenCompletedNCT00001752Phase 2
• The Role of Cyclooxygenase Activity in the Endothelial Function of Hypertensive and Hypercholesterolemic PatientsCompletedNCT00001742
• Study of the Response of Human Small Blood VesselsCompletedNCT00001622Phase 1
• Potential Risk Factors for StrokeCompletedNCT00001368Phase 1
• Cardiovascular Evaluation of Patients With High Cholesterol and Normal VolunteersCompletedNCT00001204
• Evaluation of LipoproteinsCompletedNCT00001168
• Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of LipoproteinsCompletedNCT00001154
• NHLBI Type II Coronary Intervention StudyCompletedNCT00000594Phase 3
• Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)CompletedNCT00000542Phase 3
• Women's Healthy Lifestyle Project: Cardiovascular Risk Factors and MenopauseCompletedNCT00000532Phase 3
• Cholesterol Reduction in Seniors Program (CRISP)CompletedNCT00000477Phase 2
• Lifestyle Heart TrialCompletedNCT00000471Phase 2
• Postmenopausal Estrogen/Progestin Interventions (PEPI)CompletedNCT00000466Phase 3
• Dietary Intervention Study in Children (DISC)CompletedNCT00000459Phase 3