National Institutes of Health: Hepatitis C, Chronic trials

The registry lists 23 Hepatitis C, Chronic studies with National Institutes of Health as lead sponsor. 0 are open to participants now and 12 have results posted.

Phase 1 3Phase 2 11Phase 3 3Phase 4 5No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected With Different Hepatitis C Virus Genotypes During Therapy With Sofosbuvir and GS-5816CompletedNCT02468648Phase 2Results posted
• Community-based Treatment of Chronic Hepatitis C Monoinfection and Coinfection With HIV in the District of ColumbiaCompletedNCT02339038Phase 4Results posted
• Evaluation of Safety, Tolerability, and Antiviral Activity of Chlorcyclizine HCl in Patients With Chronic Hepatitis CCompletedNCT02118012Phase 1/2Results posted
• New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis CCompletedNCT01888900Phase 2Results posted
• Combination Therapy for Chronic Hepatitis C InfectionCompletedNCT01805882Phase 2Results posted
• High-Dose Ribavirin and Peginterferon to Treat Chronic Hepatitis C Genotype 1CompletedNCT00735969Phase 2Results posted
• S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis CCompletedNCT00475176Phase 2Results posted
• Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver TransplantCompletedNCT00135694Phase 2Results posted
• PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis CCompletedNCT00100659Phase 3Results posted
• Low-Dose Peginterferon and Ribavirin to Treat Chronic Hepatitis C in Patients Infected With HCV Genotype 2 or 3CompletedNCT00056862Phase 4Results posted
• Pegylated Interferon and Ribavirin to Treat Chronic Hepatitis C With and Without Kidney DiseaseCompletedNCT00028093Phase 4Results posted
• Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard TreatmentCompletedNCT00006164Phase 3Results posted
• People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral AgentsActive, not recruitingNCT03520660Phase 4
• Hepatitis B Reactivation During Treatment With Direct-Acting Antiviral Agents for Chronic Hepatitis C InfectionCompletedNCT03248622
• Deciphering the Mechanisms Involved in Microbial Translocation Across the Spectrum of HCV Associated Liver FibrosisCompletedNCT02400216
• Viral Kinetics and Liver Gene Expression in Response to Ribavirin and Peginterferon Therapy of Chronic Hepatitis CCompletedNCT00718172Phase 1
• Phase II Trial of Silymarin for Patients With Chronic Hepatitis C Who Have Failed Conventional Antiviral TreatmentCompletedNCT00680342Phase 2
• Hepatitis C Treatment and AtherosclerosisCompletedNCT00659256
• IdB 1016 Treatment for Hepatitis C DiseaseCompletedNCT00055445Phase 1/2
• Evaluating Silymarin for Chronic Hepatitis CCompletedNCT00030030Phase 2
• Gamma Interferon Therapy for Chronic Hepatitis CCompletedNCT00028275Phase 2
• Long-Term Therapy With Ribavirin for Chronic Hepatitis CCompletedNCT00001854Phase 4
• Combination Drug Therapy for Patients With Hepatitis CCompletedNCT00001729Phase 3