National Institutes of Health: Hepatitis trials

The registry lists 115 Hepatitis studies with National Institutes of Health as lead sponsor. 0 are open to participants now and 40 have results posted.

Phase 1 15Phase 2 48Phase 3 15Phase 4 8No phase 37(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Safety Study of Hepatitis E Vaccine (HEV239)CompletedNCT03827395Phase 1Results posted
• HEPLISAV-B Hepatitis B Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's-Tyrosine Kinase Inhibitor (BTK-I)CompletedNCT03685708Phase 2Results posted
• Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda InterferonCompletedNCT03600714Phase 2Results posted
• Treatment of Chronic Delta Hepatitis With Lonafarnib and RitonavirCompletedNCT02511431Phase 2Results posted
• Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected With Different Hepatitis C Virus Genotypes During Therapy With Sofosbuvir and GS-5816CompletedNCT02468648Phase 2Results posted
• Add-on Peginterferon Following Nucleos(t)Ide Analogue TreatmentCompletedNCT02364336Phase 2Results posted
• Community-based Treatment of Chronic Hepatitis C Monoinfection and Coinfection With HIV in the District of ColumbiaCompletedNCT02339038Phase 4Results posted
• Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infection in HIV-Coinfected Adults on Antiretroviral TherapyTerminatedNCT02194998Phase 2Results posted
• Evaluation of Safety, Tolerability, and Antiviral Activity of Chlorcyclizine HCl in Patients With Chronic Hepatitis CCompletedNCT02118012Phase 1/2Results posted
• New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis CCompletedNCT01888900Phase 2Results posted
• Study of A Combination Pill With GS-7977 and GS-5885 for Hepatitis C in People With HIVCompletedNCT01878799Phase 2Results posted
• Combination Therapy for Chronic Hepatitis C InfectionCompletedNCT01805882Phase 2Results posted
• Lonafarnib for Chronic Hepatitis DCompletedNCT01495585Phase 2Results posted
• Evaluating the Effectiveness of Boceprevir, Pegylated-Interferon Alfa 2b and Ribavirin in Treating Hepatitis C Virus (HCV) Infection in Adults With HIV and HCV InfectionCompletedNCT01482767Phase 3Results posted
• Boceprevir Drug Combination for Hepatitis C Treatment in People With and Without HIVTerminatedNCT01443923Phase 4Results posted
• GS-7977 With Ribavirin for Hepatitis C (SPARE)CompletedNCT01441180Phase 1/2Results posted
• Staged Phase I/II Hepatitis C Prophylactic VaccineCompletedNCT01436357Phase 1/2Results posted
• Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir Versus Tenofovir Monotherapy in Chronic Hepatitis BCompletedNCT01369212Phase 3Results posted
• Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults With Chronic Hepatitis BTerminatedNCT01369199Phase 3Results posted
• Entecavir/Pegylated Interferon in Immune Tolerant Children With Chronic Hepatitis B Virus (HBV) InfectionCompletedNCT01368497Phase 3Results posted
• A Safety and Tolerability Study of Nitazoxanide in HIV-HCV Treatment FailuresCompletedNCT01185028Phase 1/2Results posted
• Open Label Study to Evaluate Chronic Hepatitis C Treatment in Latino Subjects With and Without HIV Co-infectionTerminatedNCT01182298Results posted
• Nitazoxanide Plus Ribavirin and Peginterferon for Therapy of Treatment Naive HCV Genotype 1 and HIV Coinfected SubjectsCompletedNCT00991289Phase 2Results posted
• Pioglitazone to Treat Fatty Liver in Patients With HIV and Hepatitis C InfectionsTerminatedNCT00742326Phase 4Results posted
• High-Dose Ribavirin and Peginterferon to Treat Chronic Hepatitis C Genotype 1CompletedNCT00735969Phase 2Results posted
• Tenofovir Alone Versus Tenofovir With Emtricitabine to Treat Chronic Hepatitis BTerminatedNCT00524173Phase 2Results posted
• S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis CCompletedNCT00475176Phase 2Results posted
• Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver TransplantCompletedNCT00135694Phase 2Results posted
• PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis CCompletedNCT00100659Phase 3Results posted
• Peginterferon Alpha-2a and Ribavirin to Treat Hepatitis C in HIV-infected PatientsCompletedNCT00085917Phase 2Results posted
• Pegylated Interferon Alfa-2a Maintenance Therapy and Liver Disease Progression in People Infected With Both HIV and Hepatitis C Virus (HCV)CompletedNCT00078403Phase 2Results posted
• Treating Nonalcoholic Steatohepatitis (NASH) With MetforminCompletedNCT00063232Phase 2Results posted
• Treating Nonalcoholic Steatohepatitis With PioglitazoneCompletedNCT00062764Phase 2Results posted
• Low-Dose Peginterferon and Ribavirin to Treat Chronic Hepatitis C in Patients Infected With HCV Genotype 2 or 3CompletedNCT00056862Phase 4Results posted
• Rituximab to Treat Hepatitis C-Associated Cryoglobulinemic VasculitisCompletedNCT00029107Phase 2Results posted
• Pegylated Interferon and Ribavirin to Treat Chronic Hepatitis C With and Without Kidney DiseaseCompletedNCT00028093Phase 4Results posted
• Pegylated Interferon to Treat Chronic Hepatitis DCompletedNCT00023322Phase 2Results posted
• Lamivudine and Adefovir to Treat Chronic Hepatitis BCompletedNCT00023309Phase 2Results posted
• Peginterferon Alpha-2b And Ribavirin to Treat Hepatitis C in HIV-Infected PatientsCompletedNCT00018031Phase 2Results posted
• Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard TreatmentCompletedNCT00006164Phase 3Results posted
• Peginterferon Lambda and Lonafarnib Boosted With Ritonavir 48-Week Combination Therapy for Delta HepatitisWithdrawnNCT05953545Phase 2
• Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral TherapyWithdrawnNCT04046107Phase 1/2
• Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis BWithdrawnNCT03575208Phase 2
• Effectiveness of the Hepatitis B Vaccine Post-Hematopoietic Stem Cell TransplantCompletedNCT03511794
• Hepatitis B Reactivation During Treatment With Direct-Acting Antiviral Agents for Chronic Hepatitis C InfectionCompletedNCT03248622
• Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid TumorsCompletedNCT02143401Phase 1
• Long-Term Study of Liver Disease in People With Hepatitis B and/or Hepatitis C With or Without HIV InfectionCompletedNCT01350648
• Duration of Long-term Immunity After Hepatitis B Virus ImmunizationCompletedNCT01182311
• Evaluating the Safety of ITX 5061 in Treatment-Naive Hepatitis C (HCV)-Infected AdultsCompletedNCT01165359Phase 1
• A Study of Molecular and Genetic Factors for Liver Cancer in the Greater Baltimore AreaCompletedNCT00913757
• An Hepatitis B Vaccine Model for HIV Vaccine Trials in Drug UsersCompletedNCT00841477Phase 3
• Hepatitis B and HIV Co-Infection in Patients in UgandaCompletedNCT00782158
• Viral Kinetics and Liver Gene Expression in Response to Ribavirin and Peginterferon Therapy of Chronic Hepatitis CCompletedNCT00718172Phase 1
• Phase II Trial of Silymarin for Patients With Chronic Hepatitis C Who Have Failed Conventional Antiviral TreatmentCompletedNCT00680342Phase 2
• Hepatitis C Treatment and AtherosclerosisCompletedNCT00659256
• Psychoeducation for Hepatitis and Alcohol BehaviorsCompletedNCT00598416Not applicable
• Chronic Hepatitis Intervention Project for Drug UsersCompletedNCT00596843Phase 3
• MRI to Measure Liver Fat ContentCompletedNCT00594412Not applicable
• Chiron Corp HCV E1/E2 VaccineCompletedNCT00500747Phase 1
• TG4040 in Patients With Chronic HCVWithdrawnNCT00449124Phase 1
• Study to Reduce Intravenous Exposures (STRIVE)CompletedNCT00391482Phase 2/3
• Phase I Trial of Silymarin for Chronic Liver DiseasesCompletedNCT00389376Phase 1
• Transplant-Related Accelerated Progression of Hepatitis CCompletedNCT00368225
• Association Between Hepatitis C Virus Infection and Hematologic and Thyroid CancersCompletedNCT00342641
• Genes Involved in Resistance or Susceptibility to Hepatitis B VirusCompletedNCT00342186
• Interferon-Induced Gene Expression in Liver Cells and Peripheral Blood LymphocytesCompletedNCT00324389Phase 2
• Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1CompletedNCT00249574Not applicable
• Preventing Depression in Methadone Maintenance Patients Receiving Hepatitis C Treatment - 1CompletedNCT00218556Not applicable
• Treatment of Alcohol-Related Hepatitis With ArginineWithdrawnNCT00200746Phase 2
• Treatment of Acute Hepatitis C Virus Infection With Pegylated Interferon in Injection Drug UsersCompletedNCT00194480Phase 4
• Long-Term Lamivudine Therapy for Chronic Hepatitis BCompletedNCT00120354Phase 4
• Safety of and Immune Response to a Hepatitis B Virus Vaccine Given With a Booster (CpG7909 ODN) in HIV Infected and HIV Uninfected PeopleCompletedNCT00100633Phase 1/2
• Effects of Anti-HIV Therapy on Treatment for Hepatitis C in HCV/HIV Infected AdultsCompletedNCT00100581Not applicable
• Retrovirus Epidemiology Donor Study-II (REDS-II)CompletedNCT00097006
• Leukapheresis for Research on HCV-Coinfected PatientsCompletedNCT00076427
• Racial Difference in HCV/Host InteractionsCompletedNCT00071916
• Hepatitis C: Grading and Staging by MRCompletedNCT00059397
• Prevention of Recurrent Hepatitis B After Liver TransplantationCompletedNCT00059267
• Treatment of Cholestatic Pruritus With SertralineCompletedNCT00058903Phase 2
• IdB 1016 Treatment for Hepatitis C DiseaseCompletedNCT00055445Phase 1/2
• Treatment of Hepatitis C in Hemophilic Patients With HIVCompletedNCT00055341Phase 2
• Treatment of Hepatitis B Virus (HBV) Before Beginning Anti-HIV Drugs in Patients With Both HBV and HIVWithdrawnNCT00051090Not applicable
• Treatment of Hepatitis in Patients Who Are Triple-Infected With HIV, Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV)WithdrawnNCT00051077Phase 2
• Collection of Biological Samples From Patients With Hepatitis-Associated Aplastic AnemiaCompletedNCT00050115
• Hepatitis C Antiviral Resistance in African-AmericansCompletedNCT00038974Phase 3
• Prevalence of Hepatitis C Virus Infection in HIV-Infected ChildrenCompletedNCT00037076
• A Comparison of Adefovir and Tenofovir for the Treatment of Lamivudine-Resistant Hepatitis B Virus in People With HIVCompletedNCT00033163Phase 2
• The Impact of HAART on Response to Hepatitis C Treatment in Patients Taking Peginterferon Alpha-2b and RibavirinCompletedNCT00031343Phase 2
• Evaluating Silymarin for Chronic Hepatitis CCompletedNCT00030030Phase 2
• Gamma Interferon Therapy for Chronic Hepatitis CCompletedNCT00028275Phase 2
• Lamivudine and Adefovir to Treat Chronic Hepatitis B Infection in People With and Without HIV InfectionCompletedNCT00023153Phase 3
• Study of Transfusion-Transmitted InfectionsCompletedNCT00023023
• Interleukin-2 (IL-2), Pegylated Interferon (PEG-IFN Alfa-2b), and Ribavirin (RBV) Treatment in Patients With Hepatitis C and HIV CoinfectionCompletedNCT00015652Not applicable
• Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV DrugsCompletedNCT00013871Not applicable
• Adefovir Dipivoxil to Treat Hepatitis B in HIV-Infected PatientsCompletedNCT00013702Phase 2
• Herbal Treatment of Hepatitis C in Methadone Maintained PatientsCompletedNCT00010816Phase 2
• A Comparison of the Effectiveness, Safety, and Tolerability of Two Different Hepatitis C Treatments in Patients Infected With Both HIV and Hepatitis C Virus (HCV)CompletedNCT00008463Phase 2
• Comparing Single Photon Emission Computed Tomography (SPECT) and Liver Biopsy to Evaluate the Liver in Patients With HIV and Hepatitis C VirusCompletedNCT00006643
• Immune Response to Hepatitis C VirusCompletedNCT00006301
• Genetics of Hepatitis C Virus InfectionCompletedNCT00005657