National Institutes of Health: Dementia trials

The registry lists 32 Dementia studies with National Institutes of Health as lead sponsor. 2 are open to participants now and 2 have results posted.

Phase 1 6Phase 2 5Phase 3 2Phase 4 2No phase 17(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• PET Imaging of Cyclooxygenases in Neurodegenerative Brain DiseaseRecruitingNCT04396873Phase 1
• Genetic Characterization of Movement Disorders and DementiasRecruitingNCT02014246
• Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With DementiaCompletedNCT06273917Not applicableResults posted
• PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) RadioligandTerminatedNCT03958630Phase 1Results posted
• On Site Sensors Monitoring Impacts of Cognitive Decline on ADLsStatus unknownNCT04871698
• The Genetic Characterization of DementiaCompletedNCT01867359
• Living With Frontotemporal DementiaTerminatedNCT01738386
• Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and DementiaStatus unknownNCT00966017
• Effect of Activities and Exercise on Sleep in Elderly Persons With DementiaCompletedNCT00888706Phase 2
• The Women's Health Initiative Memory Study (The WHIMS Study)CompletedNCT00685009
• PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in Frontotemporal DementiaCompletedNCT00613119
• PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)TerminatedNCT00459693Not applicable
• Double Blind Trial of DC Polarization in FTDCompletedNCT00117858Phase 2
• Polarity Therapy for American Indian Caregivers of Dementia PatientsCompletedNCT00100035Phase 1
• Treatment Study of Frontotemporal DementiaCompletedNCT00088751
• Direct Current Brain Polarization in Frontotemporal DementiaCompletedNCT00077896Phase 1
• Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)CompletedNCT00043849Phase 4
• Donepezil to Treat Dementia in Parkinson's DiseaseCompletedNCT00030979Phase 4
• Evaluation of Age- and Alzheimer's Disease-Related Memory DisorderCompletedNCT00029120
• Clinical and Genetic Studies of Familial Presenile Dementia With Neuronal Inclusion BodiesCompletedNCT00006176
• Honolulu Heart Program-Study of Stroke and DementiaCompletedNCT00005395
• Models of Disordered Knowledge and Memory Systems in Dementia and Related DisordersCompletedNCT00004557
• Sertraline for the Treatment of Patients With Frontal Lobe Dementia (FLD)CompletedNCT00001777Phase 1
• Effects of Brain Stimulation on Learning and ReasoningCompletedNCT00001776
• Treatment of Alzheimer's Disease With CX516 (Ampalex)CompletedNCT00001662Phase 2
• The Evaluation and Follow-up of Individuals With Memory DisorderCompletedNCT00001480
• Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian DisordersTerminatedNCT00001178
• A Study to Evaluate the Use of Memantine In Combination With Anti-HIV Drugs to Treat AIDS Dementia Complex (ADC)CompletedNCT00000867Phase 2
• Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1CompletedNCT00000738Phase 1
• An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte CountsCompletedNCT00000709Phase 3
• A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) InfectionCompletedNCT00000702Phase 3
• Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia ComplexCompletedNCT00000657Phase 2