National Institutes of Health: beta-Thalassemia trials

The registry lists 12 beta-Thalassemia studies with National Institutes of Health as lead sponsor. 2 are open to participants now and 1 have results posted.

Phase 1 3Phase 2 8No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Partial Stem Cell Transplant for Sickle Cell Disease From Matched DonorsRecruitingNCT07599176Phase 1/2
• Collection of Human Biospecimens for Basic and Clinical Research Into Globin VariantsRecruitingNCT03937817
• Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital AnemiasActive, not recruitingNCT00061568Phase 1/2Results posted
• Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-ThalassemiaActive, not recruitingNCT05357482Phase 1/2
• Perceptions of Thalassemia Major in Singapore: An Exploratory Study of StigmaCompletedNCT01129076
• Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or ThalassemiaTerminatedNCT00034528Phase 2
• Cord Blood Transplantation for Sickle Cell Anemia and ThalassemiaCompletedNCT00029380Phase 2
• Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia MajorCompletedNCT00006138
• 5-Azacytidine and Phenylbutyrate to Treat Severe ThalassemiaCompletedNCT00005934Phase 2
• Stem Cell Transplantation (SCT) for Genetic DiseasesCompletedNCT00004378Not applicable
• Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia)CompletedNCT00001958Phase 2
• Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional HemochromatosisCompletedNCT00000595Phase 2