National Institutes of Health: Asthma trials

The registry lists 122 Asthma studies with National Institutes of Health as lead sponsor. 10 are open to participants now and 11 have results posted.

Early Phase 1 1Phase 1 8Phase 2 16Phase 3 6Phase 4 3No phase 92(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES)Enrolling by invitationNCT07867184
• Microbiome and Atopy in MaliRecruitingNCT07051902
• A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-UpRecruitingNCT06732414
• Protocol CAUSE-03 / CHEETAHRecruitingNCT06136091
• Registry of Asthma Characterization and Recruitment 3 (RACR3)RecruitingNCT05272241
• NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)RecruitingNCT02327897
• Study of the Effect of Innate on the Inflammatory Response to EndotoxinRecruitingNCT01143480
• Personalized Environment and Genes StudyRecruitingNCT00341237
• Role of Genetic Factors in the Development of Lung DiseaseRecruitingNCT00001532
• Activation and Function of Eosinophils in Conditions With Blood or Tissue EosinophiliaRecruitingNCT00001406
• A Trial of Mepolizumab Adjunctive Therapy for the Prevention of Asthma Exacerbations in Urban ChildrenCompletedNCT03292588Phase 2Results posted
• Cockroach Nasal Allergen Challenge PilotCompletedNCT02710136Phase 1Results posted
• Subcutaneous Immunotherapy for Mouse in AdultsCompletedNCT02532179Phase 1/2Results posted
• Preventative Omalizumab or Step-up Therapy for Severe Fall ExacerbationsCompletedNCT01430403Phase 4Results posted
• Biomarkers of Cockroach Sublingual Immunotherapy 2CompletedNCT01380327Phase 1/2Results posted
• Development of Cockroach Immunotherapy by the Inner-City Asthma ConsortiumCompletedNCT01221285Phase 1Results posted
• A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory AsthmaCompletedNCT00994175Phase 2Results posted
• Biomarker-based Cockroach Sublingual Immunotherapy Study (BioCSI)CompletedNCT00829985Phase 1/2Results posted
• Sublingual Cockroach Safety in Adults With Cockroach Allergy & Perennial Allergic Rhinitis With or Without AsthmaCompletedNCT00434421Phase 1Results posted
• Inner-City Anti-IgE Therapy for AsthmaCompletedNCT00377572Phase 4Results posted
• Promoting Tolerance to Common Allergens in High-Risk Children: Global Prevention of Asthma in Children (GPAC) StudyCompletedNCT00346398Phase 2Results posted
• Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and AdolescentsActive, not recruitingNCT05347771Phase 2
• New Approaches for Empowering Studies of Asthma in Populations of African DescentCompletedNCT03937804
• Vaginal Microbiome Exposure and Immune Responses in C-section InfantsActive, not recruitingNCT03567707Early Phase 1
• Effect of Fasting and Refeeding on T-cell FateCompletedNCT02719899
• Registry for Asthma Characterization and Recruitment 2CompletedNCT02513264
• Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based TherapyCompletedNCT02502890
• Effect of Fasting on the Asthma InflammasomeCompletedNCT02471300
• Human Rhinovirus Infection and Airway Remodeling MediatorsTerminatedNCT01847768Not applicable
• Longitudinal Observational Study of Severe AsthmaCompletedNCT01780142
• The COX-2 Gene and the Immune SystemCompletedNCT01678222
• Childhood Asthma Reduction StudyWithdrawnNCT01468805Not applicable
• Agricultural Health Study Follow-upCompletedNCT01399411
• Asthma Phenotypes in the Inner CityCompletedNCT01383941
• The Role of Epigenetics in Inner City AsthmaCompletedNCT01382836
• TGF-(Beta) and Susceptibility to RSVCompletedNCT01224691
• Drug Interaction Study Between Inhaled Beclomethasone and Protease Inhibitors in Healthy VolunteersCompletedNCT00936793Phase 1
• Multisystemic Therapy to Reduce Health Disparities in Adolescents With AsthmaCompletedNCT00916240Not applicable
• Indoor Woodsmoke PM and AsthmaCompletedNCT00807183Phase 3
• Nitric Oxide, LPS and the Pathogenesis of Asthma Phase 1CompletedNCT00671229
• Biomarkers in Exhaled Breath From Asthmatic PatientsTerminatedNCT00635271
• Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat AsthmaWithdrawnNCT00604578Phase 2
• Pathogenesis and Genetics of Environmental Asthma Ozone StudyCompletedNCT00574158
• Childhood Asthma Research and Education (CARE) Network Trial - Montelukast or Azithromycin for Reduction of Inhaled Corticosteroids in Childhood Asthma (MARS)TerminatedNCT00471809Phase 4
• Children With Asthma in New Orleans After Hurricane KatrinaCompletedNCT00426634
• ICATA Asthma Mechanistic StudyCompletedNCT00377390
• Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese SingaporeansCompletedNCT00342030
• A Cohort Study of Smoking Prevention and Health Promotion for Middle School Students in Wuhan, ChinaCompletedNCT00341653
• Effect of Air Pollution on Long-Term Asthma Severity and Lung Function in ChildrenStatus unknownNCT00336050
• Childhood Asthma Research and Education (CARE) Network Trial - Acute Intervention Management Strategies (AIMS)CompletedNCT00319488Not applicable
• Treatment of Ragweed-Allergic Asthma With an Immunostimulatory DrugTerminatedNCT00318747Phase 2
• Center for Reducing Asthma Disparities - Northwestern University/Cook County Hospital CentersCompletedNCT00281177Not applicable
• Center for Reducing Asthma Disparities - Howard/Hopkins CentersCompletedNCT00281112
• Center for Reducing Asthma Disparities - Harvard University/Boston Area Community Health CentersCompletedNCT00281086
• Pediatric Asthma Controller Trial (PACT)CompletedNCT00272506Phase 3
• Prevention of Early Asthma in Kids (PEAK)CompletedNCT00272441Not applicable
• Air Pollution, Inflammation, and New Onset AsthmaCompletedNCT00241696
• Adherence Intervention for Minority Children With AsthmaCompletedNCT00233181Not applicable
• Nebulizer Intervention for Minority Children With AsthmaCompletedNCT00218816Phase 3
• Teaching Children With Asthma and Who Live in a Rural Setting How to Self-Manage Their AsthmaCompletedNCT00218803Phase 3
• Does Shared Decision-Making Improve Adherence in AsthmaCompletedNCT00217945Not applicable
• A+ Asthma Early Intervention in Asthma ManagementCompletedNCT00217906Not applicable
• The Effect of Self-regulatory Education on Women With AsthmaCompletedNCT00217802Not applicable
• Asthma Surveillance and Education in Preschool SettingsCompletedNCT00201071
• Parent-Youth Teamwork in Pediatric Asthma ManagementCompletedNCT00166582Phase 2
• Does Shared Decision-Making Improve Asthma Outcomes?CompletedNCT00149526Not applicable
• Peak Flow Monitoring in Older Adults With AsthmaCompletedNCT00149474Not applicable
• Improving Asthma Communication in Minority FamiliesCompletedNCT00133666Phase 2
• Methods of Determining Asthma Severity in ChildrenCompletedNCT00132834
• Urban Environmental Factors and Childhood AsthmaCompletedNCT00114881
• Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in AdolescentsCompletedNCT00114413Not applicable
• Complementary and Alternative Medicine Use in Low-Income African American and Caucasian Adults With AsthmaCompletedNCT00094419
• Genetic Studies in Difficult to Treat Asthma: TENORCompletedNCT00091767
• Genetic Risk Factors for Severe AsthmaCompletedNCT00090740
• Exhaled Breath Condensate as a Measure of Airway Inflammation in Children With AsthmaCompletedNCT00078208
• Outdoor Allergen Exposure, Sensitivity, and Acute AsthmaCompletedNCT00043992
• Asthma Severity in Children and Environmental AgentsCompletedNCT00042705
• Community Organizing Network for Environmental HealthCompletedNCT00042484Not applicable
• Geographic Modeling of Traffic and Asthma RatesCompletedNCT00041834
• Physical Activity, Body Composition, and Prevalent AsthmaCompletedNCT00037375
• Exposure of Children With Asthma to Household Environmental Tobacco SmokeCompletedNCT00035685
• Borage Oil and Ginkgo Biloba (EGb 761) in AsthmaCompletedNCT00029679Phase 1/2
• Magnesium and Asthma - Clinical TrialsCompletedNCT00029510Phase 2
• Reducing Indoor Allergen Exposures in Northern Manhattan and the South BronxCompletedNCT00023127Not applicable
• The Genetics of Environmental AsthmaCompletedNCT00018096Not applicable
• Recombinant Human IL-4 Receptor Used in Treatment of AsthmaCompletedNCT00017693Phase 2
• Asthma & Exposure to Peaks in Particulate Air PollutionCompletedNCT00013728
• Ozone and Rhinovirus-Induced Disease in AsthmaticsCompletedNCT00013715
• Randomized Trial to Reduce Environmental Tobacco Smoke in Children With AsthmaCompletedNCT00006565Phase 3
• Chromosome 5Q Gene Variants and Asthma-Related TraitsCompletedNCT00006511
• Identification of an Asthma Susceptibility Gene on 3PCompletedNCT00006510
• Chronic Life Stress and Incident Asthma in Adult WomenCompletedNCT00006498
• Community Based Study on Occupational AsthmaCompletedNCT00005755
• Interventions to Improve Asthma Management/Prevention at SchoolCompletedNCT00005736
• Controlling Asthma at SchoolCompletedNCT00005735
• Intervention to Improve Asthma Management/PreventionCompletedNCT00005734
• Develop and Implement Asthma Controlling Strategies (2)CompletedNCT00005733
• Develop and Implement Asthma Controlling Strategies (1)CompletedNCT00005732
• Develop and Implement Asthma Controlling StrategiesCompletedNCT00005731
• Asthma Partnership for Minority ChildrenCompletedNCT00005716