National Institute on Drug Abuse (NIDA): Tobacco Use Disorder trials
The registry lists 65 Tobacco Use Disorder studies with National Institute on Drug Abuse (NIDA) as lead sponsor. 2 are open to participants now and 4 have results posted.
Phase 1 6Phase 2 26Phase 3 7Phase 4 3No phase 28(a study in two phases counts in both)
Studies
Open to participants first, then studies with results posted, then the rest; newest registration first within each.
- Orexin s Role in the Neurobiology of Substance Use DisorderRecruitingNCT05630781Not applicable
- Advanced Functional and Structural MRI Techniques for Neuropharmacological ImagingRecruitingNCT01036581Not applicable
- The Study of AZD8529 for Smoking Cessation in Female SmokersCompletedNCT02401022Phase 2Results posted
- Nicotine Withdrawal Symptoms and Smoking RelapseCompletedNCT01511614Not applicableResults posted
- Selegiline for Smoking Cessation - 1CompletedNCT00439413Phase 2Results posted
- Effectiveness of Bupropion for Treating Nicotine Dependence in Young PeopleCompletedNCT00129272Phase 2Results posted
- State and Trait Mediated Response to TMS in Substance Use DisorderWithdrawnNCT03707600Not applicable
- Brain Networks and Addiction SusceptibilityCompletedNCT01924468Phase 1
- Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverityCompletedNCT01867411
- Tobacco Cessation: Treatment Delivery and Predictors of OutcomeWithdrawnNCT01859364
- Studying Nicotine Addiction With Transcranial Magnetic StimulationCompletedNCT01702948
- Pexacerfont to Reduce Stress-induced Tobacco CravingWithdrawnNCT01557556
- Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic PolymorphismsCompletedNCT01505725
- Nicotinic Modulation of the Default Network of Resting Brain FunctionCompletedNCT01240616
- Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco DependenceCompletedNCT01208935Phase 2/3
- Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Adolescent SmokersCompletedNCT01148355
- Assessing Top Down and Bottom Up Attention Mechanisms in Smokers Using Nicotine Nasal SprayCompletedNCT01136642Phase 1
- The Neural Basis of Cue-Elicited Cigarette Craving and Its ControlCompletedNCT01048957Not applicable
- fMRI Study of Nicotinic Effect on Neurophysiology of SchizophreniaCompletedNCT01046526
- PET Imaging of Nicotinic Acetylcholine ReceptorsCompletedNCT01046513
- Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smokers and in Heavy and Light Situational SmokersCompletedNCT01038245
- Effects of Nicotine on Brain Activity as Measured by fMRICompletedNCT01037153
- Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRICompletedNCT01036711
- Cognitive Task Development and Implementation for Functional MRI StudiesCompletedNCT01036685
- Effects of Nicotine on Areas of Impaired and Preserved Functioning in SchizophreniaCompletedNCT01034085
- Effects of Nicotine on Elements of Attentions in Smokers and NonsmokersCompletedNCT01034020Phase 1
- Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine AddictionCompletedNCT01031693Phase 1
- Assessment of Craving in Nicotine-Dependent Patients With Schizophrenia Using Virtual RealityCompletedNCT01031433
- Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From NonsmokersCompletedNCT01031121
- A Multi-Modal Investigation of the Smoking Cessation Medication Varenicline: Dopaminergic Modulation of Reward Processing and Cognitive ControlCompletedNCT00830739
- Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal NicotineCompletedNCT00777569Phase 2
- Reduction of Smoking in Cardiac Disease PatientsCompletedNCT00469885Phase 2
- Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who SmokeCompletedNCT00307203Phase 4
- Efficacy and Safety of Bupropion for Treatment of Adolescent SmokingTerminatedNCT00248118Phase 2/3
- Nicotine Lozenge to Reduce Smokeless Tobacco UseCompletedNCT00218283Phase 2
- Effectiveness of Using Tobacco Free Snuff in Reducing Negative Effects of Smokeless Tobacco UseCompletedNCT00218270Phase 2
- Using Smokeless Tobacco Products With Lower Nicotine Levels to Reduce Negative Effects of Smokeless Tobacco UseCompletedNCT00218244Phase 1/2
- Effect of Bupropion on Smoking Behavior in Smokers With SchizophreniaCompletedNCT00218231Phase 2
- Effects of Transdermal Nicotine on Smoking, Craving and Withdrawal in People With SchizophreniaCompletedNCT00218218Phase 2
- Naltrexone Augmentation of Nicotine Patch Therapy - 1CompletedNCT00218153Phase 3
- Effectiveness of the Nicotine Patch in Suppressing Nicotine Withdrawal Symptoms in Women Versus Men - 1CompletedNCT00218140Phase 2
- Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1CompletedNCT00158171Phase 2
- Effectiveness of Reducing Smoking in Facilitating Smoking Cessation in Adolescents - 2CompletedNCT00158158Phase 2/3
- Assessing the Variability Over Time of Tobacco Carcinogen Biomarkers in Smokers - 2CompletedNCT00158145
- Bupropion as an Adjunct to the Nicotine Patch Plus CBTCompletedNCT00142831Phase 4
- Nicotine and Cotinine Levels in Smokers With Schizophrenia and Schizoaffective Disorder - 2CompletedNCT00135772
- Examining the Effectiveness of the Nicotine Patch in Male and Female Smokers - 2CompletedNCT00135746Not applicable
- A Survey on Consumer Use of Over-the-Counter (OTC) Nicotine PatchesCompletedNCT00134927
- Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1CompletedNCT00124683Phase 2
- Nicotine Replacement Treatment for Pregnant Smokers - 1TerminatedNCT00115687Phase 2
- Behavioral Smoking Cessation Treatment - 1CompletedNCT00110825Not applicable
- Smoking Treatment of PrisonersCompletedNCT00110630Phase 3
- Maintaining Abstinence in Chronic Cigarette Smokers - 1CompletedNCT00087880Phase 2
- Incentive Programs for Female Substance Abusers Who Smoke - 3CompletedNCT00064922Phase 2/3
- Maintenance Treatment for Abstinent SmokersCompletedNCT00063323Phase 3
- Combination Pharmacotherapy for Smoking Cessation Among Methadone PatientsCompletedNCT00060814Phase 2
- Chemical Dependency and Smoking Cessation: Patient's Views - 1CompletedNCT00051883
- Nicotine Patch for Nicotine Dependence in Individuals With Schizophrenia or Schizoaffective Disorder - 1TerminatedNCT00046813Phase 4
- Effects of Stimulant Dependence on Human Striatal Dopamine System - 15Status unknownNCT00000350Phase 1
- Effects of Labetalol on Nicotine Administration in Humans - 14CompletedNCT00000297Phase 2
- Role of Metabolites in Nicotine Dependence (4) - 13CompletedNCT00000296Phase 2
- Progesterone Treatment in Female Smokers - 12CompletedNCT00000295Phase 2
- Role of Metabolites in Nicotine Dependence (3) - 6CompletedNCT00000289Phase 2
- Role of Metabolites in Nicotine Dependence (2) - 5CompletedNCT00000288Phase 2
- Role of Metabolites in Nicotine Dependence (1) - 1CompletedNCT00000284Phase 2