National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Liver Diseases trials

The registry lists 23 Liver Diseases studies with National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) as lead sponsor. 4 are open to participants now and 6 have results posted.

Phase 1 1Phase 2 5Phase 3 4No phase 14(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell TransplantNot yet recruitingNCT05722210
• Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research ApproachRecruitingNCT04685200
• Natural History of Noncirrhotic Portal HypertensionRecruitingNCT02417740
• Evaluation of Patients With Liver DiseaseRecruitingNCT00001971
• Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda InterferonCompletedNCT03600714Phase 2Results posted
• Losartan for the Treatment of Pediatric NAFLDTerminatedNCT03467217Phase 2Results posted
• Cysteamine Bitartrate Delayed-Release for the Treatment of NAFLD in ChildrenCompletedNCT01529268Phase 2/3Results posted
• The Farnesoid X Receptor (FXR) Ligand Obeticholic Acid in NASH Treatment Trial(FLINT)CompletedNCT01265498Phase 2Results posted
• Treatment of Nonalcoholic Fatty Liver Disease in Children (TONIC)CompletedNCT00063635Phase 3Results posted
• Pioglitazone vs Vitamin E vs Placebo for Treatment of Non-Diabetic Patients With Nonalcoholic Steatohepatitis (PIVENS)CompletedNCT00063622Phase 3Results posted
• Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Liver DiseaseCompletedNCT05669677
• TReatment for ImmUne Mediated PathopHysiologyActive, not recruitingNCT04862221Phase 2
• Longitudinal Assessment of Transient Elastography in Cystic FibrosisCompletedNCT03001388
• MRI to Characterize and Predict CF Liver Disease in PUSH CohortCompletedNCT02979340
• Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver DiseaseCompletedNCT02520609
• Palmitate Breath Test to Assess Fatty Acid Oxidation in Non Alcoholic Fatty Liver Disease (NAFLD)CompletedNCT02363309
• Comparing Pain in Patients Undergoing Percutaneous Versus Transjugular Techniques of Liver BiopsyCompletedNCT02311348
• Evaluation of Sickle Cell Liver DiseaseCompletedNCT01950429
• The Physiology of Fatigue in Patients With Chronic Liver DiseaseCompletedNCT01867385
• Detection and Cytotoxic T Lymphocyte Therapy of Post-Transplant Lymphoproliferative Disorder After Liver TransplantCompletedNCT00063648Phase 1
• Gabapentin to Treat Itch in Patients With Liver DiseaseCompletedNCT00058890Phase 3
• Genetics of Hepatitis C Virus InfectionCompletedNCT00005657
• Diagnosis and Treatment of Patients With Cystic FibrosisTerminatedNCT00001223