National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Insulin Resistance trials

The registry lists 23 Insulin Resistance studies with National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) as lead sponsor. 3 are open to participants now and 4 have results posted.

Phase 1 1Phase 2 7Phase 4 2No phase 13(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With ObesityNot yet recruitingNCT05713799Phase 2
• Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin ResistanceRecruitingNCT05470504Phase 2
• Genetic Studies of Insulin and DiabetesRecruitingNCT00001987
• Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in People With Insulin Receptor MutationsCompletedNCT02457897Phase 2Results posted
• Myocardial Function & FFA Metabolism in HIV Metabolic SyndromeCompletedNCT00656851Not applicableResults posted
• The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy VolunteersCompletedNCT00339833Phase 4Results posted
• Effect of Metreleptin Therapy in the Treatment of Severe Insulin ResistanceActive, not recruitingNCT00085982Phase 2Results posted
• Effect of Isocaloric Ultra Processed Versus Unprocessed Diets on Insulin SensitivityCompletedNCT03189121
• Identifying Risk for Diabetes and Heart Disease in WomenCompletedNCT01809288
• Metabolic Effects of Steroids in Obese MenStatus unknownNCT00983554Not applicable
• Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CTCompletedNCT00958815
• Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH MenCompletedNCT00470990Not applicable
• Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes MellitusCompletedNCT00445627
• Insulin Sensitivity in Men With the Metabolic SyndromeSuspendedNCT00433173Not applicable
• Substrate Cycling in Energy MetabolismCompletedNCT00361751Phase 2
• Fat Cell Size in Insulin ResistanceCompletedNCT00341406
• Cross-Sectional and Longitudinal Studies of "Pre-Diabetes" in the Pima IndiansCompletedNCT00340132
• Insulin Resistance in Severely Obese PatientsCompletedNCT00275223
• Insulin Resistance and Central Nervous System (CNS) Function in Type 2 DiabetesCompletedNCT00212290Phase 4
• The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese ChildrenCompletedNCT00108901Phase 2
• Insulin Resistance and Insulin SecretionWithdrawnNCT00073294Not applicable
• Leptin to Treat Severe Insulin Resistance - Pilot StudyCompletedNCT00027456Phase 2
• Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy SyndromeCompletedNCT00006185Phase 1