National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Hepatitis C trials

The registry lists 25 Hepatitis C studies with National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) as lead sponsor. 1 are open to participants now and 10 have results posted.

Phase 1 2Phase 2 8Phase 3 4Phase 4 4No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Evaluation of Patients With Liver DiseaseRecruitingNCT00001971
• Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected With Different Hepatitis C Virus Genotypes During Therapy With Sofosbuvir and GS-5816CompletedNCT02468648Phase 2Results posted
• Evaluation of Safety, Tolerability, and Antiviral Activity of Chlorcyclizine HCl in Patients With Chronic Hepatitis CCompletedNCT02118012Phase 1/2Results posted
• New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis CCompletedNCT01888900Phase 2Results posted
• High-Dose Ribavirin and Peginterferon to Treat Chronic Hepatitis C Genotype 1CompletedNCT00735969Phase 2Results posted
• S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis CCompletedNCT00475176Phase 2Results posted
• Pre-Transplant Treatment to Prevent Recurrence of Hepatitis C After Liver TransplantationCompletedNCT00135798Phase 2Results posted
• PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis CCompletedNCT00100659Phase 3Results posted
• Low-Dose Peginterferon and Ribavirin to Treat Chronic Hepatitis C in Patients Infected With HCV Genotype 2 or 3CompletedNCT00056862Phase 4Results posted
• Pegylated Interferon and Ribavirin to Treat Chronic Hepatitis C With and Without Kidney DiseaseCompletedNCT00028093Phase 4Results posted
• Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard TreatmentCompletedNCT00006164Phase 3Results posted
• People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral AgentsActive, not recruitingNCT03520660Phase 4
• Hepatitis B Reactivation During Treatment With Direct-Acting Antiviral Agents for Chronic Hepatitis C InfectionCompletedNCT03248622
• Long-term Follow-up of HALT-C Sustained Virological RespondersCompletedNCT00825877
• Viral Kinetics and Liver Gene Expression in Response to Ribavirin and Peginterferon Therapy of Chronic Hepatitis CCompletedNCT00718172Phase 1
• Hepatitis C Treatment and AtherosclerosisCompletedNCT00659256
• Hepatitis C: Grading and Staging by MRCompletedNCT00059397
• Treatment of Cholestatic Pruritus With SertralineCompletedNCT00058903Phase 2
• Hepatitis C Antiviral Resistance in African-AmericansCompletedNCT00038974Phase 3
• Gamma Interferon Therapy for Chronic Hepatitis CCompletedNCT00028275Phase 2
• Immune Response to Hepatitis C VirusCompletedNCT00006301
• Genetics of Hepatitis C Virus InfectionCompletedNCT00005657
• History of Hepatitis C in Volunteer Blood DonorsCompletedNCT00001982
• Long-Term Therapy With Ribavirin for Chronic Hepatitis CCompletedNCT00001854Phase 4
• Combination Drug Therapy for Patients With Hepatitis CCompletedNCT00001729Phase 3