National Cancer Institute (NCI): Carcinoma in Situ trials

The registry lists 16 Carcinoma in Situ studies with National Cancer Institute (NCI) as lead sponsor. 0 are open to participants now and 11 have results posted.

Early Phase 1 1Phase 1 9Phase 2 5Phase 3 1No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Bexarotene in Preventing Breast Cancer in Patients at High Risk for Breast CancerCompletedNCT03323658Phase 1Results posted
• Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)CompletedNCT03258593Phase 1Results posted
• Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial LesionsTerminatedNCT03197025Phase 1Results posted
• Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial NeoplasiaCompletedNCT03196180Early Phase 1Results posted
• Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast CancerTerminatedNCT02876640Phase 1Results posted
• E7 TCR T Cells for Human Papillomavirus-Associated CancersCompletedNCT02858310Phase 1/2Results posted
• Nelipepimut-S Plus GM-CSF Vaccine Therapy in Treating Patients With Breast CancerCompletedNCT02636582Phase 2Results posted
• Study of Docosahexaenoic Acid (DHA) in Triple Negative Breast Cancer SurvivorsCompletedNCT01849250Phase 2Results posted
• Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone LumpectomyCompletedNCT00769379Phase 3Results posted
• Lapatinib Ditosylate in Treating Patients With Ductal Breast Carcinoma In SituCompletedNCT00555152Not applicableResults posted
• Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial NeoplasiaCompletedNCT00303823Phase 2Results posted
• E7 TCR T Cell Immunotherapy for High-Grade Cervical Intraepithelial NeoplasiaWithdrawnNCT04411134Phase 1
• Letrozole in Preventing Breast Cancer in Healthy Postmenopausal Women at High Risk for Breast CancerCompletedNCT01077453Phase 1
• A Phase I Prevention Study of Atorvastatin in Women at Increased Risk for Breast CancerCompletedNCT00637481Phase 1
• Vaccine Therapy in Preventing Cervical Cancer in Patients With Cervical Intraepithelial NeoplasiaCompletedNCT00054041Phase 2
• Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial NeoplasiaTerminatedNCT00005808Phase 1