Memorial Sloan Kettering Cancer Center: Precursor Cell Lymphoblastic Leukemia-Lymphoma trials

The registry lists 26 Precursor Cell Lymphoblastic Leukemia-Lymphoma studies with Memorial Sloan Kettering Cancer Center as lead sponsor. 4 are open to participants now and 6 have results posted.

Early Phase 1 1Phase 1 10Phase 2 14Phase 3 1Phase 4 1No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Cord Blood Transplantation in Children and Young Adults With Blood CancerRecruitingNCT07566377Phase 2
• A Study of Obecabtagene Autoleucel in People With B-cell Acute Lymphoblastic LeukemiaRecruitingNCT07400029Phase 2
• A Study of Revumenib and Mezigdomide in People With LeukemiaRecruitingNCT07356154Phase 1/2
• A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)RecruitingNCT06287528Phase 1
• Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched DonorsTerminatedNCT03615105Phase 2Results posted
• Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood TransplantationCompletedNCT03434730Phase 2Results posted
• Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic SyndromeCompletedNCT01200355Phase 4Results posted
• HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic MalignanciesCompletedNCT01119066Phase 2Results posted
• Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic DisordersCompletedNCT00587054Phase 2Results posted
• Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or LymphomaCompletedNCT00002766Phase 3Results posted
• Cord Blood Transplant in Adults With Blood CancersActive, not recruitingNCT05884333Phase 2
• A Study of Venetoclax in Combination With Chemotherapy to Treat Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)Active, not recruitingNCT05386576Early Phase 1
• A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow TransplantActive, not recruitingNCT04872595Phase 2
• Blinatumomab and Tyrosine Kinase Inhibitor Therapy in People With Philadelphia Chromosome-Positive Acute Lymphoblastic LeukemiaActive, not recruitingNCT04329325Phase 2
• Intravenous Erwinia Chrysanthemi Asparaginase in Patients With Newly Diagnosed Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia Aged 60 Years or OlderWithdrawnNCT02647190Phase 1
• Adding Ruxolitinib to a Combination of Dasatinib Plus Dexamethasone in Remission Induction Therapy in Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Patients Aged 40 Years or OlderActive, not recruitingNCT02494882Phase 1
• In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell MalignanciesActive, not recruitingNCT01430390Phase 1
• Precursor B Cell Acute Lymphoblastic Leukemia (B-ALL) Treated With Autologous T Cells Genetically Targeted to the B Cell Specific Antigen CD19Active, not recruitingNCT01044069Phase 1
• Induction Therapy With Cytarabine, High-Dose Mitoxantrone and Dasatinib for Patients With Philadelphia-Chromosome Positive (Ph+) Acute Lymphoblastic LeukemiaCompletedNCT00940524Phase 1
• Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With RadiotherapyCompletedNCT00606216
• Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute LeukemiaCompletedNCT00462787Phase 1
• Arsenic Trioxide and Imatinib Mesylate in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Philadelphia Chromosome-Positive Acute Lymphoblastic LeukemiaCompletedNCT00081133Phase 1/2
• PS-341 in Treating Patients With Hematologic CancerCompletedNCT00006098Phase 1
• Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia, Osteosarcoma, or Non-Hodgkin's LymphomaCompletedNCT00002738Phase 2
• T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients With Leukemia, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, or Aplastic AnemiaCompletedNCT00002718Phase 2
• Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's LymphomaCompletedNCT00002471Phase 2