McMaster University: Asthma trials

The registry lists 16 Asthma studies with McMaster University as lead sponsor. 4 are open to participants now and 1 have results posted.

Phase 1 1Phase 2 2Phase 3 3Phase 4 3No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• The Safety, Feasibility, and Repeatability of Inhaled ATP Cough ChallengesRecruitingNCT07085975Phase 1
• Therapeutic Relevance of Abnormal Airway Morphology in AsthmaRecruitingNCT06970080Phase 4
• Canadian Consortium on Airway Mucus Occlusions in Asthma, COPD and Chronic CoughRecruitingNCT06858748
• Measurements of Inflammation Induced by Allergen Inhalation Challenge in Mild Allergic AsthmaNot yet recruitingNCT06411886Not applicable
• Mepolizumab for the Treatment of Chronic Cough With Eosinophilic Airways DiseasesCompletedNCT04765722Phase 4Results posted
• Tezepelumab and Methacholine Airway Hyperresponsiveness in Participants With Mild Allergic AsthmaStatus unknownNCT05740748Phase 2
• IL-13 Blockade and Airway Autoimmunity in AsthmaCompletedNCT05564078
• Tezepelumab on Airway Structure and Function in Patients With Uncontrolled Moderate-to-severe AsthmaCompletedNCT05280418Phase 3
• Efficacy of Reslizumab Dose Escalation in Patients With Severe AsthmaCompletedNCT04710134Phase 4
• Assessment of SOLO Vibrating Mesh Nebulizer for Allergen-Induced Late Asthmatic ResponsesStatus unknownNCT04630405Not applicable
• COVID-19 Related Lung Ventilation and Perfusion InjuryCompletedNCT04549636
• Dupilumab on Airway Hyper-responsiveness and Ventilation Heterogeneity in Patients With Asthma.CompletedNCT03884842Phase 3
• Mannitol-Induced Cough Challenge in Healthy Controls and Subjects With Mild Allergic AsthmaCompletedNCT03620422Not applicable
• Anti-Interleukin-5 (IL5) Monoclonal Antibody (MAb) in Prednisone-dependent Eosinophilic AsthmaCompletedNCT02559791Phase 2/3
• Airway Pressure During Humidified High Flow Nasal Cannula Therapy in ChildrenCompletedNCT02387632
• Causes, Characteristics and Mechanisms of Infective Exacerbations in Subjects With Asthma and Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT00512954