Massachusetts General Hospital: Lung Neoplasms trials

The registry lists 52 Lung Neoplasms studies with Massachusetts General Hospital as lead sponsor. 16 are open to participants now and 18 have results posted.

Early Phase 1 1Phase 1 9Phase 2 18Phase 3 1No phase 28(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Stepped Intervention for Coping With Dyspnea in Patients With Lung Cancer-Phase A (Open Pilot)Not yet recruitingNCT07728773Not applicable
• LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol ANot yet recruitingNCT07685028Not applicable
• LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol BRecruitingNCT07600801
• Ivonescimab Alone And With Carboplatin/Pemetrexed For NSCLCRecruitingNCT07405190Phase 2
• A Digital Health Intervention to Improve Physical Function and Wellness of Lung Cancer SurvivorsRecruitingNCT07227623Not applicable
• Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CTRecruitingNCT06910956Not applicable
• Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung CancerRecruitingNCT06791057Not applicable
• EB-OCT Biopsy Guidance of Lung CancerNot yet recruitingNCT06556680Not applicable
• Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung CancerRecruitingNCT06427954Not applicable
• The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)RecruitingNCT06412172
• Lung Cancer Screening in High-risk Black IndividualsRecruitingNCT05898594Not applicable
• Health Opportunities and Promoters of Equitable Screening for Lung CancerRecruitingNCT05784922
• Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue InjuryRecruitingNCT04485286Phase 2
• Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis PatientsRecruitingNCT03535545Phase 1
• Boston Lung Cancer Study (Molecular and Genetic Analysis of Lung Cancer)RecruitingNCT03029325
• DNA Analysis of Blood and Tissue From Patients With Lung CancerRecruitingNCT00471978
• Lung Cancer Screening Navigation for Homeless PeopleCompletedNCT04308226Not applicableResults posted
• Early Integrated Telehealth Versus In-Person Palliative Care for Patients With Lung CancerCompletedNCT03375489Not applicableResults posted
• Stepped Palliative Care Versus Early Integrated Palliative Care in Patients With Advanced Lung CancerCompletedNCT03337399Not applicableResults posted
• A Study of EGF816 and Gefitinib in TKI-naïve EGFR-mutant Non-Small Cell Lung CancerTerminatedNCT03292133Phase 2Results posted
• Nivolumab in Combination With Chemotherapy, or Nivolumab in Combination With Ipilimumab, in Advanced EGFR-Mutant or ALK-Rearranged NSCLCCompletedNCT03256136Phase 2Results posted
• Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung CancerCompletedNCT03089125Not applicableResults posted
• A Study of Capmatinib (INC280) in NSCLC Patients With MET Exon 14 Alterations Who Have Received Prior MET InhibitorCompletedNCT02750215Phase 2Results posted
• Phase I/II Trial of Alectinib and Bevacizumab in Patients With Advanced, Anaplastic Lymphoma Kinase (ALK)-Positive, Non-Small Cell Lung CancerTerminatedNCT02521051Phase 1/2Results posted
• Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung CancerCompletedNCT02394548Not applicableResults posted
• Ponatinib in Advanced NSCLC w/ RET TranslocationsCompletedNCT01813734Phase 2Results posted
• AUY922 for Advanced ALK-positive NSCLCCompletedNCT01752400Phase 2Results posted
• Early Palliative Care in Advanced Lung and Gastrointestinal MalignanciesCompletedNCT01401907Not applicableResults posted
• IPI-504 in NSCLC Patients With ALK TranslocationsTerminatedNCT01228435Phase 2Results posted
• Hydroxychloroquine With or Without Erlotinib in Advanced Non-small Cell Lung Cancer (NSCLC)TerminatedNCT01026844Phase 1Results posted
• Carboplatin, Abraxane, and Bevacizumab in Previously Untreated Patients With Advanced Non-Small Cell Lung CancerCompletedNCT00642759Phase 2Results posted
• Smoking Cessation Intervention for Thoracic PatientsCompletedNCT00580398Phase 1/2Results posted
• Erlotinib in Patients With Resected, Early Stage NSCLC With Confirmed Mutations in the EGFRCompletedNCT00567359Phase 2Results posted
• Escitalopram in Treating Depression in Patients With Advanced Lung or Gastrointestinal CancerTerminatedNCT00387348Phase 3Results posted
• Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery DownloadCompletedNCT05346380Phase 1/2
• The Transitions Project: Efficacy TrialActive, not recruitingNCT05087251Not applicable
• Supportive Care Mobile Application for Patients With NSCLCCompletedNCT04629300Not applicable
• Lung Cancer Risk and Early Detection in FirefightersCompletedNCT04614129Not applicable
• Immune Checkpoint Inhibitors and Atherosclerotic Plaque VolumeCompletedNCT04430712
• Lorlatinib Combinations in Lung CancerStatus unknownNCT04292119Phase 1/2
• Niraparib in Combination With Osimertinib in EGFR-Mutated Advanced Lung CancerTerminatedNCT03891615Phase 1
• Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor TherapyCompletedNCT03290677Not applicable
• Study of Stepped Palliative Care in Patients With Advanced Lung Cancer DF/HCC SOCIAL-BEHAVIORAL RESERACH PROTOCOLTerminatedNCT03220100Not applicable
• A Phase IB/II Study of Alectinib Combined With Cobimetinib in Advanced ALK-Rearranged (ALK+) NSCLCActive, not recruitingNCT03202940Phase 1/2
• A Study of Lorlatinib in Advanced ALK and ROS1 Rearranged Lung Cancer With CNS Metastasis in the Absence of Measurable Extracranial LesionsStatus unknownNCT02927340Phase 2
• Improving Management of Breathlessness in Patients With Lung CancerCompletedNCT01937637Not applicable
• Proton Radiation Therapy With Cisplatin and Etoposide Followed by Surgery in Stage III Non-Small Cell Lung CancerTerminatedNCT01565772Phase 1
• Proton Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung CancerTerminatedNCT01525446Early Phase 1
• Pilot Study to Evaluate Optical Frequency Domain Imaging for Diagnosis of Central Airway DiseaseCompletedNCT01396603
• Integrated Versus Standard Palliative Care in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)CompletedNCT01038271Not applicable
• A Randomized Study to Evaluate the Effect of Two Different Doses of Enoxaparin Sodium in Combination With Standard Chemotherapy in Patients With Stage Small Cell Lung Cancer (SCLC)WithdrawnNCT00916669Phase 2
• Gefitinib in Treating Patients With Previously Untreated Stage IIIB or Stage IV Non-Small Cell Lung CancerCompletedNCT00411047Phase 2