Massachusetts General Hospital: Diabetes Mellitus, Type 1 trials

The registry lists 27 Diabetes Mellitus, Type 1 studies with Massachusetts General Hospital as lead sponsor. 1 are open to participants now and 16 have results posted.

Phase 1 2Phase 2 10Phase 3 4Phase 4 1No phase 14(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Genetically Informed Screening for Early-Stage Type 1 DiabetesNot yet recruitingNCT07802496
• The Insulin-Only Bionic Pancreas Bridging Study- Pediatric Transitional StudyCompletedNCT04112069Not applicableResults posted
• The Bihormonal iLet Bionic Pancreas Feasibility StudyCompletedNCT03840278Phase 2/3Results posted
• The Insulin-Only Bionic Pancreas Bridging StudyCompletedNCT03565666Phase 2/3Results posted
• Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic PancreasTerminatedNCT03262116Phase 2/3Results posted
• Efficacy of Glucagon In the Prevention of Hypoglycemia During Mild ExerciseTerminatedNCT03217175Not applicableResults posted
• The Monitoring StudyCompletedNCT02969863Not applicableResults posted
• The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic PancreasTerminatedNCT02701257Not applicableResults posted
• Effect of Ethanol Intoxication on the Anti-Hypoglycemic Action of GlucagonCompletedNCT02516150Phase 4Results posted
• Multicenter Trial of the Effect of AAT on Islet Transplant Engraftment and Durability After Renal TransplantCompletedNCT02464878Phase 2Results posted
• The Summer Camp Study 2: Blood Glucose Control With a Bi-Hormonal Endocrine PancreasCompletedNCT02105324Not applicableResults posted
• A Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic PancreasCompletedNCT02092220Not applicableResults posted
• The Summer Camp Study: Blood Glucose Control With a Bi-Hormonal Bionic Endocrine PancreasCompletedNCT01833988Not applicableResults posted
• Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine PancreasCompletedNCT01762059Not applicableResults posted
• Selecting Insulin Analogs for Closed-Loop Control Using Multiplex Pharmacokinetic ProfilingCompletedNCT01684943Not applicableResults posted
• Study of Islet Transplantation in Type 1 Diabetic Kidney Transplant RecipientsCompletedNCT00888628Phase 1/2Results posted
• Comparison of Lantus and Neutral Protamine Hagedorn (NPH) Insulin in the Dawn PhenomenonCompletedNCT00694122Phase 3Results posted
• The T1D Parent Check-In: A Preventative InterventionActive, not recruitingNCT06160934Not applicable
• Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 YearsActive, not recruitingNCT05866536Phase 2
• Understanding and Optimizing Care for Young Adults With Type 1 and Type 2 Diabetes Mellitus Transitioning to Adult CareCompletedNCT05229718Not applicable
• Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 DiabetesActive, not recruitingNCT05180591Phase 2
• Collection of Breath and Sweat to Identify Indicators of HypoglycemiaCompletedNCT03600116
• Bone Health in Youth With Type 1 DiabetesStatus unknownNCT02140424
• Repeat BCG Vaccinations for the Treatment of Established Type 1 DiabetesActive, not recruitingNCT02081326Phase 2
• Pharmacokinetic Comparison of Intradermal Versus Sub-cutaneous Insulin and Glucagon Delivery in Type 1 DiabetesStatus unknownNCT01684956Phase 2
• Cognitive Behavioral Therapy (CBT) for Adherence and Depression in Type 1 DiabetesCompletedNCT01527981Phase 2
• Determination of Dosing and Frequency of BCG Administration to Alter T-Lymphocyte Profiles in Type I DiabeticsCompletedNCT00607230Phase 1