Massachusetts General Hospital: Breast Neoplasms trials

The registry lists 50 Breast Neoplasms studies with Massachusetts General Hospital as lead sponsor. 9 are open to participants now and 12 have results posted.

Early Phase 1 1Phase 1 7Phase 2 11No phase 33(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Non-Contrast-Enhanced Breast MRI in the Evaluation of Newly Diagnosed Breast Cancer: A Pilot StudyNot yet recruitingNCT07874256Not applicable
• Wearable Ultrasound Patch for Breast ImagingNot yet recruitingNCT07186491Not applicable
• Targeted Palliative Care Intervention for Patients With Metastatic Breast CancerRecruitingNCT06795529Not applicable
• Low-field MRI for Breast Cancer ScreeningEnrolling by invitationNCT05486520Not applicable
• Early InterventionNot yet recruitingNCT05326165Not applicable
• Screening For BCRL In Targeted Therapy For Breast CancerRecruitingNCT05142800
• Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical TrialRecruitingNCT03990896Phase 2
• Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast CancerRecruitingNCT02290834Not applicable
• Prospective Screening for Breast Cancer-related LymphedemaRecruitingNCT01521741
• Culturally Aware AET Non-Initiation InterventionCompletedNCT05465408Not applicableResults posted
• Patient Experiences With the COVID-19 Vaccination After Breast Cancer TreatmentCompletedNCT04872738Results posted
• Small-group, Virtual Program for Improving Symptoms and Distress Related to Hormonal Therapy for Breast Cancer SurvivorsCompletedNCT03837496Not applicableResults posted
• Breast Cancer Detection: Comparison of Breast Tomosynthesis and Conventional MammographyCompletedNCT01669148Not applicableResults posted
• External-Beam Partial-Breast Irradiation for Early Breast Cancer 40 Gy QD Over 2 WeeksCompletedNCT01581619Not applicableResults posted
• Cabozantinib in Women With Metastatic Hormone-Receptor-Positive Breast CancerCompletedNCT01441947Phase 2Results posted
• Proton Radiation Therapy for Invasive Breast Cancer Following MastectomyCompletedNCT01340495Not applicableResults posted
• Early Detection and Intervention for Mild and Moderate Lymphedema in Patients Treated for Breast CancerTerminatedNCT00959985Not applicableResults posted
• Partial Breast Irradiation (PBI) for Selected Patients With Early Invasive or Non-Invasive Breast CancerCompletedNCT00694577Not applicableResults posted
• Preoperative Cisplatin and Bevacizumab in ER-, PR-, HER2 Negative Breast CancerCompletedNCT00580333Phase 2Results posted
• Intermittent Letrozole Therapy in Postmenopausal Women With Metastatic Breast CancerTerminatedNCT00549822Phase 2Results posted
• Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of ResponseCompletedNCT00483223Phase 2Results posted
• Ultrahypofractionation and Normal Tissue ToxicityActive, not recruitingNCT05912231Not applicable
• Breast Cancer Survivor Educational InterventionCompletedNCT05700396Not applicable
• Losartan in Prevention of Radiation-Induced Heart FailureCompletedNCT05607017Early Phase 1
• Fulvestrant + Neratinib In Breast CancerWithdrawnNCT04901299Phase 2
• Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast CancerActive, not recruitingNCT04837209Phase 2
• Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced CancerCompletedNCT04670445Not applicable
• Prolonged Nightly Fasting in Breast Cancer SurvivorsCompletedNCT04330339Not applicable
• Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.Active, not recruitingNCT04039230Phase 1/2
• AKT Inhibitor, Ipatasertib, With Endocrine and CDK 4/6 Inhibitor for Patients With Metastatic Breast Cancer (TAKTIC)Active, not recruitingNCT03959891Phase 1
• A Phase I Study of Niraparib Administered Concurrently With Postoperative RT in Triple Negative Breast Cancer PatientsActive, not recruitingNCT03945721Phase 1
• Exploring the Efficacy and Feasibility of the LymphaTech Scanner for Breast Cancer-Related Lymphedema ScreeningActive, not recruitingNCT03861975Not applicable
• A Pilot Study of Tomographic Optical Breast Imaging (DBT-TOBI) to Monitor Response to Neoadjuvant TherapyActive, not recruitingNCT03822312Not applicable
• Topical Calcipotriene Treatment for Breast Cancer ImmunopreventionTerminatedNCT03596073Phase 1
• Feasibility of an Individualized Goals of Care Discussion Guide for Advanced Breast CancerCompletedNCT03375827Not applicable
• PVX-410 Vaccine Plus Pembrolizumab in HLA-A2+ Metastatic Triple Negative Breast CancerActive, not recruitingNCT03362060Phase 1
• Preoperative Accelerated Partial Breast Irradiation for Triple Negative Breast Cancer Using Proton Beam ScanningWithdrawnNCT03340402Not applicable
• CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast CancerActive, not recruitingNCT03285412Phase 2
• The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage II-III Breast Cancer PatientsActive, not recruitingNCT03270072
• Adjuvant PVX-410 Vaccine and Durvalumab in Stage II/III Triple Negative Breast CancerActive, not recruitingNCT02826434Phase 1
• Palliative and Oncology Care Model in Breast CancerCompletedNCT02730858Not applicable
• Digital Breast Tomosynthesis Guided Tomographic Optical Breast Imaging (TOBI)Status unknownNCT02033486Not applicable
• Non-Invasive Imaging for Cording in Breast Cancer PatientsCompletedNCT01427166Not applicable
• Treatment of T1N0 Invasive Breast Carcinoma by Local Excision ImplantCompletedNCT00977275Phase 1/2
• Drug Withdrawal in Women With Progressive Breast Cancer While on Aromatase Inhibitor TherapyCompletedNCT00916162
• Biomarkers in Predicting Response to Tamoxifen and Letrozole in Postmenopausal Women With Primary Breast Cancer Treated on Clinical Trial CAN-NCIC-MA17Status unknownNCT00897065
• A Mammography FastTrack Program in Increasing the Number of Women Undergoing Breast Cancer ScreeningCompletedNCT00462891Not applicable
• Neoadjuvant Chemotherapy Using Doxorubicin and Paclitaxel in Treating Women With Large Breast CancerCompletedNCT00096291Phase 2
• Magnetic Resonance Imaging of Lymph Nodes Using Ferumoxytol in Patients With Primary Prostate or Breast CancerCompletedNCT00087347
• Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast CancerCompletedNCT00084669Not applicable