Johnson & Johnson: Arthritis, Rheumatoid trials

The registry lists 73 Arthritis, Rheumatoid studies with Johnson & Johnson as lead sponsor. 1 are open to participants now and 28 have results posted.

Early Phase 1 1Phase 1 7Phase 2 16Phase 3 21Phase 4 6No phase 22(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))RecruitingNCT06631638Not applicable
• A Study to Evaluate the Nipocalimab and Certolizumab Combination Therapy in Participants With Active Rheumatoid ArthritisCompletedNCT06028438Phase 2Results posted
• A Proof-of-concept Study of the Efficacy and Safety of Nipocalimab in Participants With Active Rheumatoid ArthritisCompletedNCT04991753Phase 2Results posted
• Actis Total Hip System 2 Year Follow-upCompletedNCT02783274Not applicableResults posted
• Usability of an AI for M923 in Subjects With Moderate to Severe RACompletedNCT02722044Phase 3Results posted
• A Study Comparing Sirukumab (CNTO 136) Monotherapy With Adalimumab (HUMIRA®) Monotherapy in the Treatment of Active Rheumatoid ArthritisCompletedNCT02019472Phase 3Results posted
• A Golimumab Phase 3b, Multicenter, Assessment of Intravenous Efficacy in Rheumatoid Arthritis Subjects Who Have Diminished Disease Control Despite Treatment With Infliximab (REMICADE®)TerminatedNCT01962974Phase 3Results posted
• Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003CompletedNCT01856309Phase 3Results posted
• A Study of CNTO 136 (Sirukumab) Administered Subcutaneously in Japanese Patients With Active Rheumatoid Arthritis Unresponsive to Methotrexate or SulfasalazineCompletedNCT01689532Phase 3Results posted
• A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate TherapyCompletedNCT01645280Phase 2Results posted
• A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)CompletedNCT01606761Phase 3Results posted
• A Study of CNTO 136 (Sirukumab), Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Disease-Modifying Antirheumatic Drug (DMARD) Therapy (SIRROUND-D)CompletedNCT01604343Phase 3Results posted
• Study of Subcutaneous Golimumab in Chinese Patients With Active Rheumatoid Arthritis Despite Methotrexate TherapyCompletedNCT01248780Phase 3Results posted
• Efficacy of NNC0142-0002 in Subjects With Rheumatoid Arthritis (RA)CompletedNCT01181050Phase 2Results posted
• Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)CompletedNCT01004432Phase 3Results posted
• An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate TherapyCompletedNCT00973479Phase 3Results posted
• First-in-man Trial of NNC0142-0002 in Patients With Rheumatoid ArthritisCompletedNCT00927927Phase 1Results posted
• An Efficacy and Safety Study of Infliximab in Participants With Rheumatoid ArthritisCompletedNCT00896168Phase 4Results posted
• An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis ParticipantsCompletedNCT00760669Results posted
• A Study of Effectiveness and Safety of CNTO 136 in Patients With Active Rheumatoid Arthritis Despite Methotrexate TherapyCompletedNCT00718718Phase 2Results posted
• RESTART C0168Z05 Rheumatoid Arthritis StudyCompletedNCT00714493Phase 4Results posted
• A Study of Safety and Effectiveness of Golimumab in Participants With Active Rheumatoid Arthritis Despite Methotrexate TherapyCompletedNCT00361335Phase 3Results posted
• A Study of the Safety and Efficacy of Golimumab (CNTO 148) in Subjects With Active Rheumatoid Arthritis Previously Treated With Biologic Anti-TNFa Agent(s)CompletedNCT00299546Phase 3Results posted
• Gamma Vacuum Foil (GVF) Versus Cross-linked Polyethylene in Total Knee Arthroplasty StudyCompletedNCT00289133Not applicableResults posted
• Randomized Fixed Bearing vs Mobile Bearing Cruciate Substituting TKACompletedNCT00289107Not applicableResults posted
• Randomized Fixed Bearing vs Mobile Bearing Cruciate Retaining TKACompletedNCT00289094Not applicableResults posted
• An Efficacy and Safety Study of Golimumab in Patients With Active Rheumatoid Arthritis Despite Methotrexate TherapyCompletedNCT00264550Phase 3Results posted
• A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Methotrexate-naiveCompletedNCT00264537Phase 3Results posted
• An Efficacy and Safety Study of CNTO 148 Subcutaneous Injection Compared With Placebo in Patients With Active Rheumatoid ArthritisCompletedNCT00207714Phase 2Results posted
• A Study of JNJ-67484703 in Participants With Active Rheumatoid ArthritisCompletedNCT04985812Phase 1
• Golimumab for Adherence in Rheumatoid ArthritisCompletedNCT03729349
• Tracking Biologics Along the Silk RoadCompletedNCT03006198
• Comparative and Pragmatic Study of Golimumab Intravenous (IV) (Simponi Aria) Versus Infliximab (Remicade) in Rheumatoid ArthritisCompletedNCT02728934
• Registry for Analysis of Compliance in Colombian Participants With Rheumatoid Arthritis Exposed to GolimumabTerminatedNCT02414984
• A Clinical Trial Study of Knee System in Primary Total Knee Arthroplasty in ChinaCompletedNCT02399046Not applicable
• Observational Study of Golimumab Intravenous InfusionTerminatedNCT02390700
• An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate TherapyCompletedNCT01909427Phase 2
• A Synovial Biopsy Study of JNJ-38518168 in Participants With Active Rheumatoid Arthritis Despite Methotrexate TherapyTerminatedNCT01862224Phase 2
• A Study to Assess the Safety and Effectiveness of Golimumab in Filipino Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing SpondylitisWithdrawnNCT01692457
• A Dose Range Finding Study of JNJ-38518168 in Patients With Active Rheumatoid Arthritis in Spite of Treatment With MethotrexateTerminatedNCT01679951Phase 2
• A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid ArthritisCompletedNCT01636557Phase 1
• A Study of JNJ-40346527 in Patients With Active Rheumatoid Arthritis Despite Disease-modifying Antirheumatic Drug TherapyCompletedNCT01597739Phase 2
• A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With MethotrexateWithdrawnNCT01480388Phase 2
• A Study to Investigate How JNJ-38518168 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis ParticipantsCompletedNCT01450982Phase 1
• A Study to Investigate How JNJ-39758979 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis ParticipantsCompletedNCT01442545Phase 1
• A Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Golimumab in Patients With Rheumatoid Arthritis (RA)CompletedNCT01362153Phase 1
• A Study to Determine the Number of Participants With Rheumatoid Arthritis (RA) Who Meet the Requirements for Treatment With Anti-Tumor Necrosis Factor α (TNFα) in a General Hospital Setting in KoreaCompletedNCT01294722
• Golimumab Safety and Surveillance Program Using the Ingenix NHI DatabaseCompletedNCT01081717
• An Efficacy and Safety Study of JNJ-38518168 in Adult Participants With Rheumatoid ArthritisTerminatedNCT00941707Phase 2
• A Safety and Efficacy Study of Golimumab (CNTO148) in Patients With Active Rheumatoid Arthritis (RA)CompletedNCT00771251Phase 3
• Biologic Treatment Registry Across CanadaCompletedNCT00741793
• Long-term Clinical Effectiveness of the Delta Xtend Reverse Total ShoulderTerminatedNCT00737087Not applicable
• A Safety and Efficacy Study of Golimumab (CNTO 148) in Patients With Active Rheumatoid Arthritis Despite Methotrexate TherapyCompletedNCT00727987Phase 3
• Remicade Infusion Management ProgramCompletedNCT00723905
• Analysis of Birth Outcomes of Swedish, Danish and Finnish Women Exposed to Remicade With Inflammatory Bowel Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and PsoriasisCompletedNCT00658827
• A Study to Test the Design, Functionality, and Ergonomic Features of the AutoinjectorCompletedNCT00643526Early Phase 1
• A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, in Patients With Rheumatoid Arthritis or OsteoarthritisCompletedNCT00524160Phase 4
• A Study of Oral SCIO-469 Pharmacokinetics (Study of a Drug in the Body to Watch How the Drug is Absorbed, Distributed, Metabolized and Eliminated Over a Period of Time) in the Body of Female Patients With Active Rheumatoid ArthritisCompletedNCT00508768Phase 1
• An Observational Study of Lymphoma in Patients With Rheumatoid Arthritis or Crohn's Disease.CompletedNCT00440817
• Safety and Effectiveness Study of RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid Arthritis Despite Methotrexate TherapyCompletedNCT00425321Phase 2
• APART Advanced Profiling of Anti-Rheumatic TherapiesCompletedNCT00378261Phase 4
• Open-label, Pilot Protocol of Patients With Rheumatoid Arthritis Who Switch to Infliximab After Incomplete Response to EtanerceptCompletedNCT00317538Phase 3
• Primary TKA Cruciate Retaining vs Cruciate Substituting With Rotating Platform Knee ProsthesesTerminatedNCT00289081Not applicable
• Infliximab Plus Methotrexate for the Treatment of Rheumatoid ArthritisCompletedNCT00269867Phase 3
• A Long-term Safety Study of Infliximab (Remicade)CompletedNCT00261976
• ULTRACET (Tramadol Hydrochloride and Acetaminophen) for the Treatment of Rheumatoid Arthritis Pain.CompletedNCT00246168Phase 4
• The Infliximab Rheumatoid Arthritis Methotrexate Tapering (iRAMT) ProtocolCompletedNCT00246064Phase 4
• Randomized, Double-blind, Placebo-controlled Study to Assess Fatigue in Patients With ACD Due to RA Receiving PROCRITTerminatedNCT00236678Phase 2
• A Safety and Efficacy Study for Infliximab (Remicade) With Methotrexate in Patients With Early Rheumatoid ArthritisCompletedNCT00236028Phase 3
• SPRiNG: SCIO-469 Patients With Rheumatoid Arthritis Not Receiving MethotrexateCompletedNCT00089921Phase 2
• Safety Study of SCIO-469 to Treat Patients With Active Rheumatoid Arthritis Receiving MethotrexateCompletedNCT00043732Phase 2
• A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Rheumatoid Arthritis.CompletedNCT00036387Phase 3
• A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Juvenile Rheumatoid ArthritisCompletedNCT00036374Phase 3