Jazz Pharmaceuticals: Seizures trials

The registry lists 13 Seizures studies with Jazz Pharmaceuticals as lead sponsor. 1 are open to participants now and 7 have results posted.

Phase 1 1Phase 2 4Phase 3 5Phase 4 1No phase 2(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset SeizuresRecruitingNCT07233239Phase 1
• Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic SeizuresTerminatedNCT05288283Phase 3Results posted
• Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled SeizuresTerminatedNCT04485104Phase 3Results posted
• CX-8998 for Absence SeizuresCompletedNCT03406702Phase 2Results posted
• A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)CompletedNCT02544763Phase 3Results posted
• An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)CompletedNCT02544750Phase 3Results posted
• Efficacy and Safety of GWP42003-P for Seizures Associated With Lennox-Gastaut Syndrome in Children and AdultsCompletedNCT02224560Phase 3Results posted
• Study of Intranasal Clonazepam in Adult Subjects With Epileptic SeizuresCompletedNCT00594945Phase 2Results posted
• A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis ComplexCompletedNCT05864846Phase 4
• Long-Term Follow-Up of a Cohort of Participants Prescribed Epidyolex in France in a Real-life SettingActive, not recruitingNCT05772429
• Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALYActive, not recruitingNCT05485831
• A Study of GWP42006 in People With Focal Seizures - Part ACompletedNCT02369471Phase 2
• A Study of GWP42006 in People With Focal Seizures - Part BCompletedNCT02365610Phase 2