Hoffmann-La Roche: Lupus Nephritis trials
The registry lists 11 Lupus Nephritis studies with Hoffmann-La Roche as lead sponsor. 2 are open to participants now and 7 have results posted.
Phase 1 1Phase 2 3Phase 3 7(a study in two phases counts in both)
Studies
Open to participants first, then studies with results posted, then the rest; newest registration first within each.
- A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus NephritisRecruitingNCT07598396Phase 2
- A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric ParticipantsRecruitingNCT05039619Phase 2
- A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus NephritisActive, not recruitingNCT04221477Phase 3Results posted
- A Study to Evaluate the Safety and Efficacy of Obinutuzumab Compared With Placebo in Participants With Lupus Nephritis (LN)CompletedNCT02550652Phase 2Results posted
- A Study to Evaluate Efficacy of CellCept (Mycophenolate Mofetil) in Patients With Lupus NephritisTerminatedNCT02081183Phase 3Results posted
- A Study to Evaluate Ocrelizumab in Patients With Nephritis Due to Systemic Lupus Erythematosus (BELONG)TerminatedNCT00626197Phase 3Results posted
- A Study of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis.TerminatedNCT00425438Phase 3Results posted
- A Study of Mycophenolate Mofetil (CellCept) in Management of Patients With Lupus Nephritis.CompletedNCT00377637Phase 3Results posted
- A Study to Evaluate the Efficacy and Safety of Rituximab in Subjects With International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2003 Class III or IV Lupus NephritisCompletedNCT00282347Phase 3Results posted
- A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)WithdrawnNCT06984341Phase 1
- A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Lupus Nephritis Previously Enrolled in Study U2970gWithdrawnNCT00404157Phase 3