GlaxoSmithKline: Acne Vulgaris trials

The registry lists 42 Acne Vulgaris studies with GlaxoSmithKline as lead sponsor. 0 are open to participants now and 24 have results posted.

Phase 1 15Phase 2 2Phase 3 8Phase 4 16No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• DUAC® Early Onset Efficacy Study in Japanese SubjectsCompletedNCT02557399Phase 4Results posted
• 8 Week Study to Evaluate and Compare the Efficacy and Tolerability of MAXCLARITY II and MURAD To Treat AcneCompletedNCT02524665Phase 4Results posted
• Comparison of the Efficacy and Safety of Clindamycin + Benzoyl Peroxide Formulation With Azelaic Acid Formulation in the Treatment of Acne VulgarisCompletedNCT02058628Phase 4Results posted
• A Efficacy and Safety of Duac™Compared With Clindamycin Phosphate Gel in the Treatment of Mild to Moderate Acne VulgarisCompletedNCT01915732Phase 3Results posted
• U0289-402: An Open Label, 8 Week Study to Evaluate the Efficacy and Tolerability of MAXCLARITY II in Subjects With AcneCompletedNCT01706263Phase 4Results posted
• U0289-401: Eight Week, Split-face, Study to Determine and Compare the Efficacy and Tolerability of MAXCLARITY™ II to PROACTIV™CompletedNCT01706250Phase 4Results posted
• U0289-405: An Open-Label, 12-Week Study to Evaluate the Efficacy and Safety of the Acne System (Benzoyl Peroxide 2.5%, Salicylic Acid 0.5%) in Subjects With AcneCompletedNCT01446237Not applicableResults posted
• Study STF115287, a Clinical Confirmation Study of GSK2585823 in the Treatment of Acne Vulgaris in Japanese SubjectsCompletedNCT01445301Phase 3Results posted
• Study STF115288, a Clinical Confirmation Study of GI148512 in the Treatment of Acne Vulgaris in Japanese SubjectsCompletedNCT01400932Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne - W0260-301CompletedNCT01017146Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial AcneCompletedNCT01017120Phase 3Results posted
• A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of 0.1% Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne VulgarisCompletedNCT01016977Phase 4Results posted
• Compare the Tolerance of Clindamycin 1% /Benzoyl Peroxide (BPO) 5% Gel to Clindamycin 1.2%/ BPO 2.5% Topical MedicationsCompletedNCT01015638Phase 4Results posted
• Study to Determine and Compare the Tolerance and Irritation Potential of Topical Acne MedicationsCompletedNCT00964366Phase 4Results posted
• A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial AcneCompletedNCT00964223Phase 4Results posted
• Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne MedicationsCompletedNCT00926367Phase 4Results posted
• A Clinical Study to Evaluate the Tolerability of a Topical Antibiotic and Retinoid Used in a Combined Regimen With a BPO WashCompletedNCT00891982Phase 3Results posted
• A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of AcneCompletedNCT00887484Phase 4Results posted
• Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial AcneCompletedNCT00841776Phase 4Results posted
• Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate AcneCompletedNCT00837213Phase 4Results posted
• Evaluation of Quality of Life, Efficacy, and Tolerance of Duac® Gel Compared to Differin® Gel in the Treatment of AcneCompletedNCT00807014Phase 4Results posted
• Trial of Clindamycin / Benzoyl Peroxide Gel in Subjects With AcneCompletedNCT00776919Phase 3Results posted
• Safety and Efficacy Study of Clindamycin/Benzoyl Peroxide/Tazarotene Cream in Subjects With AcneCompletedNCT00713609Phase 2Results posted
• A Clinical Study to Evaluate the Safety and Effectiveness of an Investigational Product Called CT GelCompletedNCT00689117Phase 3Results posted
• A Study to Determine Bioequivalence of Isotretinoin in Healthy Male Subjects Under Fed ConditionCompletedNCT02498288Phase 1
• Study to Investigate the Irritation Potential of GSK1940029 GelCompletedNCT01984801Phase 1
• Study to Evaluate the Safety, Tolerability and Pharmacokinetic of Single and 14 Day Repeat Topical Application of GSK1940029CompletedNCT01938482Phase 1
• W0265-103: A Single-Center, Evaluator-Blinded, Randomized, Placebo Controlled, Phase 1 Clinical Trial Evaluating The Phototoxic Potential Of Topically Applied Clindamycin 1.0% - Tretinoin 0.025% Gel (Ct Gel) In Healthy VolunteersCompletedNCT01929278Phase 1
• W0265-104: A Single-Center, Evaluator-Blinded, Randomized, Placebo-Controlled, Phase 1 Clinical Trial Evaluating the Photoallergic Potential of Topically Applied Clindamycin Phosphate 1.0% and Tretinoin 0.025% (CT Gel) in Healthy VolunteersCompletedNCT01915758Phase 1
• Bioequivalence Study for an IsotretinoinCompletedNCT01863615Phase 1
• Bioequivalence Minocycline BioequivalenceCompletedNCT01755611Phase 1
• A Study to Evaluate the Pharmacokinetics of Benzoic Acid and Hippuric Acid After Topical Administration of GSK2585823 in Japanese Subjects With Acne VulgarisCompletedNCT01527123Phase 1
• Japanese Phase 1 Study of GSK2585823CompletedNCT01428466Phase 1
• W0261-101: A Phase 1, Single Center, Randomized, Open-Label Study to Evaluate the Bioavailability of Clindamycin From Clindamycin 1%-Benzoyl Peroxide 3% Gel, Topical Gel (Clindamycin 1%- Benzoyl Peroxide 5%), and Once Daily Gel (Clindamycin 1%-Benzoyl Peroxide 5%) in Subjects With AcneCompletedNCT01132443Phase 1
• A Study to Evaluate the Potential of Tazarotene Foam to Cause an Allergic Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers.CompletedNCT01119651Phase 1
• A Study to Evaluate the Potential of Tazarotene Foam to Cause a Reaction When Applied to the Skin and Exposed to Light on Healthy VolunteersCompletedNCT01115322Phase 1
• A Study To Evaluate The Contact Sensitization Potential Of Tazarotene Foam On Skin In Healthy VolunteersCompletedNCT01114841Phase 1
• A Study to Evaluate the Irritation Potential of Tazarotene Foam on Skin in Healthy VolunteersCompletedNCT01112787Phase 1
• A Study to Evaluate the Bioavailability of Tazarotene Foam, 0.1%, and Tazorac Gel, 0.1%, in Subjects With Acne VulgarisCompletedNCT01019603Phase 1
• Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne VulgarisCompletedNCT00757523Phase 4
• An Open Label Trial to Assess the Safety and Efficacy of Oral R115866 in the Treatment Facial AcneCompletedNCT00725439Phase 2
• Comparison of Duac® Gel And Differin® Gel in Mild to Moderate Acne VulgarisCompletedNCT00160394Phase 4