ECOG-ACRIN Cancer Research Group: all 121 studies

Page 1 of 2. Open to participants first (14), then studies with results posted, then the rest; newest registration first within each.

• Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate CancerNot yet recruitingNCT07852195Phase 2/3
• Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract CancerNot yet recruitingNCT07765433Phase 2/3
• Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage MelanomaRecruitingNCT07068074Phase 3
• Sulforaphane for the Prevention of Melanoma in Patients With Multiple Atypical Nevi and a Prior History of MelanomaRecruitingNCT07040280Phase 2
• Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal CavityRecruitingNCT07001748Phase 2/3
• Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue SarcomaNot yet recruitingNCT06526897Not applicable
• Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid CancerRecruitingNCT06475989Phase 3
• Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE TrialRecruitingNCT06319027Phase 2
• Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP TrialRecruitingNCT05863195Phase 3
• Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE TrialRecruitingNCT04566328Phase 3
• Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET ImagingRecruitingNCT04423211Phase 3
• Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated BiomarkersRecruitingNCT04239573
• Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering MyelomaRecruitingNCT03937635Phase 3
• Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone SurgeryRecruitingNCT02734537Phase 2
• Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K MelanomaTerminatedNCT04527549Phase 2Results posted
• Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory PneumonitisTerminatedNCT04438382Phase 2Results posted
• Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node InvolvementTerminatedNCT04221438Phase 2Results posted
• Docetaxel or Paclitaxel in Reducing Chemotherapy-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast CancerActive, not recruitingNCT04001829Phase 2Results posted
• Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology PracticesCompletedNCT03808818Not applicableResults posted
• Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing TreatmentActive, not recruitingNCT03516942Results posted
• Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic LeukemiaActive, not recruitingNCT03504644Phase 1/2Results posted
• Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With DocetaxelActive, not recruitingNCT03419234Phase 2Results posted
• Perfusion CT in Predicting Outcomes in Ovarian, Fallopian, or Peritoneal Cancer With BevacizumabTerminatedNCT03412630Not applicableResults posted
• Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic LeukemiaActive, not recruitingNCT03253848Not applicableResults posted
• Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense BreastsActive, not recruitingNCT02933489Not applicableResults posted
• Pre-Test Genetic Education and Remote Genetic Counseling in Communicating Tumor Profiling Results to Patients With Advanced CancerCompletedNCT02823652Not applicableResults posted
• Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine CarcinomasActive, not recruitingNCT02595424Phase 2Results posted
• Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant ChemotherapyActive, not recruitingNCT02445391Phase 3Results posted
• Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract CancerCompletedNCT02412670Phase 2Results posted
• Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT02085408Phase 3Results posted
• Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With SurgeryTerminatedNCT02031536Phase 2Results posted
• Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal CancerActive, not recruitingNCT01898494Phase 2Results posted
• Docetaxel With or Without FGFR Inhibitor AZD4547 in Treating Patients With Recurrent Non-Small Cell Lung CancerCompletedNCT01824901Phase 1/2Results posted
• Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine TumorsCompletedNCT01824875Phase 2Results posted
• A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)Active, not recruitingNCT01824836Not applicableResults posted
• Afatinib After Chemoradiation and Surgery in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck at High-Risk of RecurrenceTerminatedNCT01824823Phase 2Results posted
• Reproductive Health Program in Patients With CancerActive, not recruitingNCT01806129Not applicableResults posted
• Chemotherapy Based on PET Scan in Treating Patients With Stage I or Stage II Hodgkin LymphomaTerminatedNCT01390584Phase 2Results posted
• Bendamustine Hydrochloride and Rituximab With or Without Bortezomib Followed by Rituximab With or Without Lenalidomide in Treating Patients With High-Risk Stage II, Stage III, or Stage IV Follicular LymphomaCompletedNCT01216683Phase 2Results posted
• Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By SurgeryCompletedNCT01164228Phase 2Results posted
• Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast CancerCompletedNCT01124695Phase 2Results posted
• Bevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung CancerCompletedNCT01107626Phase 3Results posted
• Rituximab and Alemtuzumab in Treating Older Patients With Progressive Chronic Lymphocytic LeukemiaTerminatedNCT01013961Phase 2Results posted
• BLP25 Liposome Vaccine and Bevacizumab After Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer That Cannot Be Removed by SurgeryCompletedNCT00828009Phase 2Results posted
• Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal CancerCompletedNCT00316888Phase 2Results posted
• Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate CancerCompletedNCT00309985Phase 3Results posted
• Postoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal CancerTerminatedNCT00303628Phase 3Results posted
• FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant MelanomaTerminatedNCT00104884Phase 2Results posted
• Levocarnitine in Treating Fatigue in Cancer PatientsCompletedNCT00091169Phase 3Results posted
• Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung CancerCompletedNCT00008385Phase 3Results posted
• High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III MelanomaCompletedNCT00003641Phase 3Results posted
• Chemotherapy, Surgery, and Radiation Therapy in Treating Patients With Gastric CancerCompletedNCT00003298Phase 2Results posted
• Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically RemovedTerminatedNCT00002525Phase 3Results posted
• Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)Active, not recruitingNCT06295367Not applicable
• Mobile Health for Adherence in Breast Cancer PatientsActive, not recruitingNCT06112613Not applicable
• Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck CancerWithdrawnNCT06084845Phase 2
• Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer SurvivorsActive, not recruitingNCT06002828
• Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR StudyActive, not recruitingNCT05863351Phase 3
• Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and NeckActive, not recruitingNCT05721755Phase 3
• Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT TrialActive, not recruitingNCT05710328Phase 2
• Intravesical BCG vs GEMDOCE in NMIBCActive, not recruitingNCT05538663Phase 3
• Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN TrialsActive, not recruitingNCT05108298Early Phase 1
• To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close MonitoringActive, not recruitingNCT04597359Phase 2
• Comparison of Chemotherapy Before and After Surgery Versus After Surgery Alone for the Treatment of Gallbladder CancerActive, not recruitingNCT04559139Phase 2/3
• Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE StudyActive, not recruitingNCT04484818Phase 3
• Cancer and Blood Pressure Management, CARISMA StudyActive, not recruitingNCT04467021Not applicable
• Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop TrialActive, not recruitingNCT04462406Phase 2
• Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE StudyActive, not recruitingNCT04316117Phase 2
• CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted TherapyActive, not recruitingNCT04266249Phase 2
• Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the BodyActive, not recruitingNCT04248452Phase 3
• Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has SpreadActive, not recruitingNCT04233866Phase 2
• Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE StudyActive, not recruitingNCT04166318Phase 2
• A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell LymphomaActive, not recruitingNCT04115631Phase 2
• Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community SettingWithdrawnNCT03804255
• Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate CancerActive, not recruitingNCT03697148Not applicable
• Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual DiseaseActive, not recruitingNCT03516279Phase 2
• Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by SurgeryActive, not recruitingNCT03493425Phase 2
• Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete RemissionActive, not recruitingNCT03267433Phase 3
• Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast CancerActive, not recruitingNCT03233191Phase 3
• DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent GlioblastomaActive, not recruitingNCT03115333Not applicable
• Fludeoxyglucose F-18 PET/CT in Predicting Response to Chemotherapy in Patients With Stage IIIA Non-small Cell Lung Cancer That Can Be Removed by SurgeryWithdrawnNCT02607423Phase 2
• Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal CancerActive, not recruitingNCT02560298Phase 2
• MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In SituActive, not recruitingNCT02352883Not applicable
• Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)Active, not recruitingNCT02201992Phase 3
• Bortezomib or Carfilzomib With Lenalidomide and Dexamethasone in Treating Patients With Newly Diagnosed Multiple MyelomaActive, not recruitingNCT01863550Phase 3
• Biomarkers in Tissue Samples From Patients With Hodgkin Lymphoma Enrolled on ECOG-2496 Clinical TrialCompletedNCT01505712
• Biomarkers in Patients With Head and Neck CancerCompletedNCT01466257
• Biomarkers in Predicting Response to Rituximab Treatment in Samples From Patients With Indolent Follicular LymphomaCompletedNCT01381705
• Biomarkers in Bone Marrow Samples From Patients With Acute Myeloid LeukemiaCompletedNCT01251159
• Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib TosylateCompletedNCT01209299
• Biomarkers of Response in Blood and Tumor Tissue Samples From Patients With Unresectable Stage IV Squamous Cell Cancer of the Head and Neck Previously Treated With Cetuximab, Cisplatin, and Radiation TherapyCompletedNCT01194635
• Biomakers in Tissue Samples From Patients With Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck Previously Treated With Cisplatin With or Without CetuximabCompletedNCT01192750
• Biomarkers in Bone Marrow and Blood Samples From Older Patients With Acute Myeloid Leukemia Treated With Cytarabine-Based TherapyCompletedNCT01169363
• Biomarkers in Tissue Samples From Patients With Breast Cancer Treated With BevacizumabCompletedNCT01156168
• Biomarkers in Tissue Samples From Patients With Ductal Breast Carcinoma in SituCompletedNCT01132560
• Biomarkers in Patients With Diffuse Large B-Cell Lymphoma Treated With Combination Chemotherapy With or Without RituximabCompletedNCT01131208
• Biomarkers in Blood Samples From Patients With Refractory Non-Small Cell Lung Cancer Previously Treated With Sorafenib TosylateCompletedNCT01124669
• Biomarkers Predicting Response in Patients With Non-Small Cell Lung Cancer Previously Treated With Erlotinib HydrochlorideCompletedNCT01123460
• Study of Tumor Tissue From Patients With Melanoma Treated on Clinical Trial EST-1690CompletedNCT00937781
• Studying Tissue Samples to Learn More About Drug Resistance in Patients With Acute Myeloid LeukemiaCompletedNCT00900380

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