Dompé Farmaceutici S.p.A: Dry Eye Syndromes trials

The registry lists 10 Dry Eye Syndromes studies with Dompé Farmaceutici S.p.A as lead sponsor. 1 are open to participants now and 8 have results posted.

Phase 2 5Phase 3 2No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye DiseaseRecruitingNCT07503886Phase 2
• A Safety and Efficacy Study of 2 Dosing Regimens of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution Compared With Vehicle in Patients With Dry Eye Disease.CompletedNCT06244316Phase 2Results posted
• Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye DiseaseCompletedNCT05136170Phase 3Results posted
• Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study)CompletedNCT05133180Phase 3Results posted
• A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry EyeCompletedNCT03982368Phase 2Results posted
• An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry EyeCompletedNCT03019627Phase 2Results posted
• Tolerability, Safety and Efficacy of Lubricin vs Sodium Hyaluronate Eye Drops in Subjects With Moderate Dry EyeCompletedNCT02510235Not applicableResults posted
• Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dry EyeCompletedNCT02507934Not applicableResults posted
• Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry EyeCompletedNCT02101281Phase 2Results posted
• Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry EyeTerminatedNCT06411132