Dana-Farber Cancer Institute: Squamous Cell Carcinoma of Head and Neck trials

The registry lists 16 Squamous Cell Carcinoma of Head and Neck studies with Dana-Farber Cancer Institute as lead sponsor. 3 are open to participants now and 5 have results posted.

Phase 1 8Phase 2 11No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Neoadjuvant Ficerafusp Alfa With Pembrolizumab in Resectable SCCRecruitingNCT07465276Phase 2
• PD-L1 t-haNK, NAI IL-15sa and Cetuximab for Recurrent, Metastatic HNSCCRecruitingNCT06239220Phase 2
• Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCCRecruitingNCT05726370Phase 2
• Neodjuvant Nivolumab and Lirilumab, Followed by Surgery, Followed by Adjuvant Nivolumab and Lirilumab, in SCCHNActive, not recruitingNCT03341936Phase 2Results posted
• Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and NeckCompletedNCT02113878Phase 1Results posted
• Docetaxel/Cisplatin/5-Fluorouracil (TPF) Human Papillomavirus (HPV) Squamous Cell Carcinoma StudyTerminatedNCT01221753Phase 2Results posted
• Abraxane in Combination With Carboplatin, Erbitux and IMRT for Locally Advanced Squamous Cancer of the Head and NeckTerminatedNCT00570674Phase 1/2Results posted
• Docetaxel in Combination With Zactima (ZD6474) in Patients With Locally Advanced Squamous Cell Carcinoma of the the Head and NeckCompletedNCT00459043Phase 2Results posted
• Risk-adapted Therapy in HPV-positive Oropharyngeal Cancer Using Circulating Tumor (ct) HPV DNA Profiling (ReACT 2.0)WithdrawnNCT07513324Phase 2
• Post-treatment Surveillance in HPV+ Oropharyngeal SCCActive, not recruitingNCT04965792
• CIML NK Cell in Head & Neck CancerCompletedNCT04290546Phase 1
• Safety Study of Afatinib and Postoperative Radiation Therapy to Treat Head and Neck CancerCompletedNCT01783587Phase 1
• Stereotactic Boost for Oropharyngeal Squamous Cell CarcinomaWithdrawnNCT01586182Phase 1/2
• C-TPF in Patients With Newly Diagnosed Locally Advanced Squamous Cell Carcinoma of the Head and NeckCompletedNCT00402545Phase 1
• Study of Docetaxel in Combination With Cisplatin and 5-Fluorouracil in Locally Advanced Squamous Cell Carcinoma of the Head and NeckCompletedNCT00139269Phase 1/2
• Study of Taxotere, Cisplatin, 5-Fluorouracil, and Leucovorin for Squamous Cell Carcinoma of the Head and NeckCompletedNCT00139243Phase 1/2