City of Hope Medical Center: Colorectal Neoplasms trials

The registry lists 40 Colorectal Neoplasms studies with City of Hope Medical Center as lead sponsor. 16 are open to participants now and 4 have results posted.

Phase 1 13Phase 2 7Phase 3 2No phase 20(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• CCR5 Targeting Leronlimab in Combination With Hepatic Arterial Infusion Floxuridine and Systemic Therapy for the Treatment of Colorectal Cancer Liver Metastases, CHAMP TrialNot yet recruitingNCT07842965Phase 1
• Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate CancerRecruitingNCT07790718Not applicable
• Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal CancerNot yet recruitingNCT07363408Phase 1
• Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT TrialRecruitingNCT07271355Phase 3
• Splicing-based Predictive Learning for Individual Chemotherapy Evaluation in Colorectal CancerRecruitingNCT07226115
• Development of a cfDNA 5mC/5hmC-based Biomarker Panel to Predict Targeted Therapy Efficacy in mCRCRecruitingNCT07224841
• cfDNA 5mC/5hmC Biomarkers to Predict Chemotherapy Response in Metastatic Colorectal CancerRecruitingNCT07224815
• Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNARecruitingNCT07224789
• Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver MetastasesRecruitingNCT07224724
• Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer PatientsRecruitingNCT07125729Not applicable
• Telehealth Intervention for Ostomy Self-ManagementRecruitingNCT06528990Phase 2
• Early Detection of Advanced Adenomas and Colorectal CancerRecruitingNCT06342440
• Early Onset Colorectal Cancer DetectionRecruitingNCT06342401
• Stage II/III Colorectal Cancer RecurrenceRecruitingNCT06314958
• Researching the Effect of Exercise on CancerRecruitingNCT04589468Not applicable
• PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric CancerRecruitingNCT04329494Phase 1
• HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of GenomicsActive, not recruitingNCT04905082Not applicableResults posted
• FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal CancerTerminatedNCT02508077Phase 2Results posted
• Cetuximab and Capecitabine in Treating Patients With Metastatic Colorectal Cancer That Failed Irinotecan TreatmentTerminatedNCT00538291Phase 2Results posted
• Liver Resection and Floxuridine Plus Fluorouracil and Leucovorin in Treating Patients With Liver Metastases From Colorectal CancerCompletedNCT00002842Phase 2Results posted
• Epigenetic Signature for CRC Early DetectionActive, not recruitingNCT07224854
• Exosome-based Detection of Molecular Residual Disease in Stage II-III Colorectal CancerCompletedNCT06654622
• STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and MelanomaWithdrawnNCT06626256Phase 1
• Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal CancerWithdrawnNCT06575725Phase 2
• Predicting Local and Distant Recurrence in T1 Colorectal CancerCompletedNCT06314971
• Early-Onset Colorectal Cancer RecurrenceCompletedNCT06271980
• Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast CancerActive, not recruitingNCT06130826Phase 1
• Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior ChemotherapyActive, not recruitingNCT05672316Phase 1/2
• FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal CancerActive, not recruitingNCT05627635Phase 1/2
• Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported OutcomesCompletedNCT04501913
• Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal CancerActive, not recruitingNCT04428905Phase 3
• Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal CancerCompletedNCT04362839Phase 1
• An Imaging Agent (I-124 M5A) in Detecting CEA-Positive Liver Metastases in Patients With Colorectal CancerCompletedNCT03993327Phase 1
• Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by SurgeryCompletedNCT03317119Phase 1
• Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family CaregiversCompletedNCT03267524Not applicable
• Durvalumab and Tremelimumab in Treating Patients With Microsatellite Stable Metastatic Colorectal Cancer to the LiverCompletedNCT03005002Phase 1
• Electronic Monitoring Device of Patient-Reported Outcomes and Function in Improving Patient-Centered Care in Patients With Gastrointestinal Cancer Undergoing SurgeryCompletedNCT02511821Not applicable
• PatientCareAnywhere Internet-Based Software in Improving Communication and Education in Patients With Cancer and Their Healthcare ProvidersCompletedNCT02408406Not applicable
• Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal CancerCompletedNCT00873275Phase 1
• Immunoscintigraphy Using Radiolabeled Monoclonal Antibody in Finding Tumor Cells in Patients With Colorectal CancerCompletedNCT00647153Phase 1