Children's Oncology Group: all 447 studies

Page 2 of 5. Open to participants first (35), then studies with results posted, then the rest; newest registration first within each.

• Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic LeukemiaCompletedNCT00372619Phase 1/2Results posted
• Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT00372593Phase 3Results posted
• Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic SyndromesCompletedNCT00369317Phase 3Results posted
• Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed RhabdomyosarcomaCompletedNCT00354835Phase 3Results posted
• High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or EctomesenchymomaCompletedNCT00354744Phase 3Results posted
• Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' TumorCompletedNCT00352534Phase 3Results posted
• Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue SarcomaCompletedNCT00346164Phase 3Results posted
• Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk MedulloblastomaCompletedNCT00336024Phase 3Results posted
• Vincristine, Carboplatin, and Etoposide or Observation Only in Treating Patients Who Have Undergone Surgery for Newly Diagnosed RetinoblastomaCompletedNCT00335738Phase 3Results posted
• Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney TumorsCompletedNCT00335556Phase 2Results posted
• Irinotecan and Temozolomide in Treating Young Patients With Recurrent NeuroblastomaCompletedNCT00311584Phase 2Results posted
• Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell TransplantCompletedNCT00309907Phase 2Results posted
• Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical TumorCompletedNCT00304070Phase 3Results posted
• Combination Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's LymphomaCompletedNCT00302003Phase 3Results posted
• Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal CancerCompletedNCT00274937Phase 3Results posted
• Radiation Therapy in Treating Young Patients With GliomasCompletedNCT00238264Phase 2Results posted
• Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With OsteosarcomaCompletedNCT00134030Phase 3Results posted
• Treating Young Patients With Newly Diagnosed, Low Stage, Lymphocyte Predominant Hodgkin DiseaseCompletedNCT00107198Phase 2Results posted
• Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT00103285Phase 3Results posted
• Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed GliomasCompletedNCT00100802Phase 2Results posted
• Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL)CompletedNCT00098839Phase 1/2Results posted
• Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or TestesCompletedNCT00096135Not applicableResults posted
• Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk MedulloblastomaCompletedNCT00085735Phase 3Results posted
• Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell TumorCompletedNCT00085098Phase 3Results posted
• hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory NeuroblastomaCompletedNCT00082758Phase 2Results posted
• Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular RetinoblastomaCompletedNCT00079417Phase 3Results posted
• Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade GliomaCompletedNCT00077207Not applicableResults posted
• Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic LeukemiaCompletedNCT00075725Phase 3Results posted
• Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk RhabdomyosarcomaCompletedNCT00075582Phase 3Results posted
• Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular RetinoblastomaCompletedNCT00072384Phase 3Results posted
• Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood FibrosarcomaTerminatedNCT00072280Phase 2Results posted
• Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of TumorsCompletedNCT00070109Phase 2Results posted
• Sulindac and Tamoxifen in Treating Patients With Desmoid TumorCompletedNCT00068419Phase 2Results posted
• Cyclophosphamide, Rituximab, and Either Prednisone or Methylprednisolone in Treating Patients With Lymphoproliferative Disease After Solid Organ TransplantationCompletedNCT00066469Phase 2Results posted
• Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of OsteosarcomaCompletedNCT00066365Phase 2Results posted
• Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of TumorsCompletedNCT00061893Phase 2Results posted
• Comparison of Two Combination Chemotherapy Regimens With Either Vincristine or Vinblastine in Treating Patients With Advanced Anaplastic Large Cell LymphomaCompletedNCT00059839Phase 3Results posted
• Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or LymphomaCompletedNCT00057811Phase 2Results posted
• Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell TumorsCompletedNCT00053352Phase 3Results posted
• Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell TumorsCompletedNCT00047320Phase 2Results posted
• Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With NeuroblastomaCompletedNCT00033293Phase 3Results posted
• Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for EpendymomaCompletedNCT00027846Phase 2Results posted
• Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's DiseaseCompletedNCT00025259Phase 3Results posted
• Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic LymphomaCompletedNCT00004228Phase 3Results posted
• A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute LeukemiaWithdrawnNCT07498465Phase 1
• Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine GliomaActive, not recruitingNCT06894979Phase 1
• Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk NeuroblastomaWithdrawnNCT06858501Phase 2
• Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the BodyTerminatedNCT06820957Phase 2/3
• A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at HomeSuspendedNCT06639958Not applicable
• Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar CarcinomaSuspendedNCT06620302Phase 1/2
• A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory LeukemiaActive, not recruitingNCT05761171Phase 2
• Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or LymphomaActive, not recruitingNCT05602194Phase 3
• Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic SyndromeActive, not recruitingNCT05457556Phase 3
• Vincristine Pharmacokinetics in InfantsActive, not recruitingNCT05359237
• A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to TreatWithdrawnNCT05320380Phase 1/2
• Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With CancerActive, not recruitingNCT05228275
• Genetic Overlap Between Anomalies and Cancer in Kids in the Children's Oncology Group: The COG GOBACK StudyActive, not recruitingNCT05071859
• Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVETerminatedNCT05020951
• A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk RhabdomyosarcomaActive, not recruitingNCT04994132Phase 3
• A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine GliomaActive, not recruitingNCT04978727Phase 1
• A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for a Brain TumorActive, not recruitingNCT04939597Phase 3
• Financial Distress During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United StatesActive, not recruitingNCT04928599
• HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With EpendymomaActive, not recruitingNCT04903080Phase 1
• Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid LeukemiaActive, not recruitingNCT04258943Phase 1/2
• Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 MutationActive, not recruitingNCT04203316Phase 2
• A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by SurgeryActive, not recruitingNCT04195399Phase 2
• Inherited Genetic Susceptibility in Langerhans Cell Histiocytosis (LCH)Active, not recruitingNCT04100408
• Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep StudyActive, not recruitingNCT04089358Phase 3
• Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid LeukemiaActive, not recruitingNCT03817398Phase 2
• Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After SurgeryActive, not recruitingNCT03533582Phase 3
• Genetic Mutational Analysis of Saliva or Buccal Mucosa Samples From Patients With Embryonal or Alveolar RhabdomyosarcomaActive, not recruitingNCT03296371
• Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma SurvivorsCompletedNCT03206450
• Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic LeukemiaCompletedNCT03204916
• Late Effects After Treatment in Patients With Previously Diagnosed High-Risk NeuroblastomaActive, not recruitingNCT03057626
• Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPGActive, not recruitingNCT03033992Not applicable
• Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaActive, not recruitingNCT03007147Phase 3
• Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic LeukemiaActive, not recruitingNCT02981628Phase 2
• Identifying, Understanding, and Overcoming Barriers to the Use of Clinical Practice Guidelines in Pediatric OncologyCompletedNCT02847130
• Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven MedulloblastomaActive, not recruitingNCT02724579Phase 2
• MLN8237 to Treat Children With Relapsed/Refractory Solid TumorsCompletedNCT02444884Phase 1
• Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk NeuroblastomaActive, not recruitingNCT02176967Phase 3
• VEGF Receptor Tyrosine Kinase Inhibitor Axitinib in Children With Recurrent or Refractory Solid TumorsCompletedNCT02164838Phase 1
• Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid TumorsWithdrawnNCT02011126Phase 2
• Genetic Biomarkers in Saliva Samples From Patients With Ewing SarcomaCompletedNCT01876303
• Gene Analysis in Studying Susceptibility to Wilms TumorCompletedNCT01808079
• Genetic Biomarkers in Tissue Samples From Patients With OsteosarcomaCompletedNCT01807143
• Biomarker Expression in Tissue Samples From Patients With Bone SarcomasCompletedNCT01807052
• Biomarker Differences in Samples From Patients With Undifferentiated SarcomasCompletedNCT01802125
• Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed LymphomasCompletedNCT01793233
• Biomarkers in Patients With Advanced RhabdomyosarcomaCompletedNCT01668095
• Studying Biomarkers in Samples From Younger Patients With Acute Myeloid LeukemiaCompletedNCT01642121
• Studying Biomarkers in Samples From Younger Patients With Kidney CancerWithdrawnNCT01642095
• Studying Genes in Samples From Younger Patients With Acute Megakaryoblastic LeukemiaCompletedNCT01642069
• Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 TrialCompletedNCT01629745
• Studying RNA in Samples From Younger Patients With T-Cell Acute Lymphoblastic LeukemiaCompletedNCT01626183
• Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With RhabdomyosarcomaCompletedNCT01626170
• Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic LeukemiaCompletedNCT01625143
• Studying Genes Associated With Non-Hodgkin Lymphoma in Young PatientsCompletedNCT01623856
• Studying Biomarkers in Urine Samples From Younger Patients With Wilms TumorCompletedNCT01614808
• Studying Protein Expression in Tissue Samples From Younger Patients With RhabdomyosarcomaCompletedNCT01609803

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