Children's Oncology Group: Astrocytoma trials

The registry lists 22 Astrocytoma studies with Children's Oncology Group as lead sponsor. 0 are open to participants now and 4 have results posted.

Phase 1 11Phase 2 6Phase 3 2No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 MutationsActive, not recruitingNCT03581292Phase 2Results posted
• Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade GliomasCompletedNCT02323880Phase 1Results posted
• Radiation Therapy in Treating Young Patients With GliomasCompletedNCT00238264Phase 2Results posted
• Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed GliomasCompletedNCT00100802Phase 2Results posted
• Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine GliomaActive, not recruitingNCT06894979Phase 1
• A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine GliomaActive, not recruitingNCT04978727Phase 1
• Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or LymphomaCompletedNCT01273090Phase 1
• Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain TumorsCompletedNCT00919750
• Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical TrialCompletedNCT00890435
• Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to TreatmentWithdrawnNCT00458744Phase 1
• Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade GliomaCompletedNCT00352495Phase 1
• Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid TumorsCompletedNCT00138216Phase 1
• Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS TumorsCompletedNCT00107458Phase 1
• High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade GliomasCompletedNCT00078988Phase 3
• Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine GliomaCompletedNCT00028795Phase 2
• Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant GliomaCompletedNCT00006024Phase 1
• Irinotecan in Treating Children With Refractory Solid TumorsCompletedNCT00004078Phase 2
• Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid TumorsCompletedNCT00003597Phase 1
• Vinorelbine in Treating Children With Recurrent or Refractory CancersCompletedNCT00003234Phase 2
• Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord TumorsCompletedNCT00003141Phase 1
• Combination Chemotherapy in Treating Children With Progressive Brain TumorsCompletedNCT00002944Phase 3
• Development of Strategies to Increase Enrollment in Clinical Trials for Children With CancerCompletedNCT00002485