Centre for Addiction and Mental Health: Depressive Disorder, Treatment-Resistant trials

The registry lists 14 Depressive Disorder, Treatment-Resistant studies with Centre for Addiction and Mental Health as lead sponsor. 5 are open to participants now and 0 have results posted.

Phase 1 1Phase 2 4Phase 3 1Phase 4 1No phase 7(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant DepressionRecruitingNCT07211438Phase 2
• Accelerated vs. Conventional Theta Burst Stimulation for Late-life DepressionRecruitingNCT06854367Not applicable
• Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)RecruitingNCT06518720Phase 2
• Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)RecruitingNCT06512220Phase 2
• E-field Guided iTBS for Treatment Resistant DepressionRecruitingNCT05583747Not applicable
• Psilocybin for Treatment-Resistant Depression in AutismActive, not recruitingNCT06731621Phase 1
• Does Psilocybin Require Psychedelic Effects to Treat Depression?CompletedNCT05710237Phase 2
• RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)CompletedNCT05531591Phase 4
• Accelerated TBS in Late Life DepressionStatus unknownNCT05119699Not applicable
• MAO-B Occupancy in Depressed PatientsCompletedNCT04841798Not applicable
• Minocycline as Adjunctive Treatment for Treatment Resistant DepressionCompletedNCT03947827Phase 3
• Efficacy of Convulsive Therapies During ContinuationCompletedNCT03711019Not applicable
• Evaluating the Efficacy of Magnetic Seizure Therapy in Treatment Resistant Depression.WithdrawnNCT01748708Not applicable
• Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive DisorderCompletedNCT01596608Not applicable