Biosplice Therapeutics, Inc.: Osteoarthritis trials
The registry lists 10 Osteoarthritis studies with Biosplice Therapeutics, Inc. as lead sponsor. 0 are open to participants now and 8 have results posted.
Phase 1 1Phase 2 4Phase 3 4No phase 1(a study in two phases counts in both)
Studies
Open to participants first, then studies with results posted, then the rest; newest registration first within each.
- 3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Knee OsteoarthritisTerminatedNCT04931667Phase 3Results posted
- A Long-Term Safety and Efficacy Study of Lorecivivint in Subjects With Osteoarthritis of the KneeTerminatedNCT04520607Phase 3Results posted
- Patient-Reported Outcomes in Evaluating Lorecivivint (SM04690) for Moderate to Severe Knee Osteoarthritis (STRIDES-1)CompletedNCT04385303Phase 3Results posted
- Patient-Reported and Radiographic Outcomes in Evaluating Lorecivivint (SM04690) for the Treatment of Knee OsteoarthritisCompletedNCT03928184Phase 3Results posted
- Safety and Bone Health Study of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee OsteoarthritisCompletedNCT03727022Phase 2Results posted
- MRI Study to Evaluate the Safety and Efficacy of SM04690 for Knee OsteoarthritisTerminatedNCT03706521Phase 2Results posted
- A Study Evaluating the Safety and Efficacy of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee OsteoarthritisCompletedNCT03122860Phase 2Results posted
- A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis SubjectsCompletedNCT02536833Phase 2Results posted
- An Observational Study Evaluating the Safety, Tolerability, and Efficacy of Treatment of SM04690 or Placebo Previously Injected in the Target Knee Joint of Subjects With Moderately to Severely Symptomatic OsteoarthritisCompletedNCT02951026
- Phase 1, Dose Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SM04690 in Moderate to Severe Knee Osteoarthritis (OA)CompletedNCT02095548Phase 1