Beijing Friendship Hospital: Lymphohistiocytosis, Hemophagocytic trials

The registry lists 22 Lymphohistiocytosis, Hemophagocytic studies with Beijing Friendship Hospital as lead sponsor. 7 are open to participants now and 0 have results posted.

Phase 1 1Phase 2 2Phase 3 11No phase 10(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Prospective Single-Arm Clinical Trial of GO Regimen for HLH.RecruitingNCT07339345Phase 2/3
• A Study on Efficacy and Safety of iNK Cells for CAEBV /EBV-HLH After Allo-HSCTNot yet recruitingNCT06491719Not applicable
• Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal InvolvementNot yet recruitingNCT06131489
• GTP Regimen in the Treatment of Refractory/Recurrent HLHNot yet recruitingNCT06038422Phase 3
• Efficacy and Safety of Carrimycin Tablets in HLH Patients With Carbapenem-resistant InfectionsNot yet recruitingNCT05988177Not applicable
• Efficacy and Safety of Venetoclax Combined With Dexamethasone and Etoposide in HLHRecruitingNCT05546060Phase 1
• L-DEP/DEP Regimen and PD-1 Antibody as a Treatment for Relapse/Refractory EBV-HLHNot yet recruitingNCT05315336Phase 3
• Prospective Study of Immune Function and PD-1 Antibody Therapy Efficacy Predictors on CAEBV and EBV-HLH PatientsStatus unknownNCT05841342
• L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLHCompletedNCT05775705Not applicable
• Response Prediction in EBV-HLH Using Metabonomics AnalysisStatus unknownNCT05677178
• Sensitivity and Specificity of Cytokines in the Diagnosis of Lymphoma-associated HLHCompletedNCT05600959
• Clinical Study of Donor EBV-CTL Infusion in Patients With CAEBV and EBV-HLH After Allo-HSCTStatus unknownNCT05532826Not applicable
• Rituximab Monotherapy for EBV-HLH and CAEBVStatus unknownNCT05384743Phase 3
• DEP Combine With PD-1 Antibody as an Treatment for EBV-HLHStatus unknownNCT05164978Not applicable
• Chidamide Combines With VP-16 and Methylprednisolone in the Treatment of HLHStatus unknownNCT05137522Not applicable
• Ruxolitinib as a Salvage Therapy for Hemophagocytic LymphohistiocytosisStatus unknownNCT04120090Phase 3
• Pegylated Liposomal Doxorubicin as a Induction Therapy for Lymphoma Induced Hemophagocytic Lymphohistiocytosis.Status unknownNCT04077905Phase 3
• Etoposide in the First-line Treatment of Adult EBV-HLHStatus unknownNCT03742115Phase 3
• DEP-Ru Regimen as a Salvage Therapy for HLHStatus unknownNCT03533790Phase 3
• L-DEP as an Initial Treatment for EBV-HLHStatus unknownNCT02912702Phase 3
• Splenectomy as a Treatment for Patient With Relapsed Haemophagocytic Lymphohistiocytosis of Unknown EtiologyStatus unknownNCT02862054Phase 2/3
• L-DEP Regimen as a Salvage Therapy for Refractory Epstein Barr Virus-induced Hemophagocytic LymphohistiocytosisStatus unknownNCT02631109Phase 3