Amgen: all 1,085 studies

Page 1 of 11. Open to participants first (51), then studies with results posted, then the rest; newest registration first within each.

• Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or OverweightNot yet recruitingNCT07871409Phase 3
• Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 DiabetesNot yet recruitingNCT07866066Phase 3
• A Phase 3 Study of Inebilizumab in Participants With Primary Membranous NephropathyRecruitingNCT07851220Phase 3
• Comparing the Extent to Which Two Maridebart Cafraglutide Drug Products Are Made Available in the Body After a Single Subcutaneous DoseNot yet recruitingNCT07832799Phase 1
• Comparing the Extent to Which Romosozumab (AMG 785) is Made Available in the Body When Administered as a Single SC Injection or as 2 SC InjectionsRecruitingNCT07811999Phase 1
• A Trial Assessing the Effectiveness of Evolocumab in Reducing the Plaque Burden in Participants With Subclinical AtheromaNot yet recruitingNCT07803679Phase 4
• Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC)RecruitingNCT07778316Phase 3
• A Phase 1 Trial of AMG 691 in Healthy Chinese and Japanese VolunteersRecruitingNCT07745907Phase 1
• A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Previously Untreated Primary Immune Thrombocytopenia (ITP)RecruitingNCT07700238Phase 3
• Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)RecruitingNCT07684235Phase 3
• Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)RecruitingNCT07684144Phase 3
• A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular DegenerationRecruitingNCT07614776Phase 3
• A Trial of Inebilizumab in Participants With Autoimmune HepatitisRecruitingNCT07598825Phase 3
• A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes MellitusRecruitingNCT07590193Phase 1
• Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)RecruitingNCT07575399Phase 3
• Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)RecruitingNCT07531095Phase 1
• Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate CancerRecruitingNCT07493512Phase 1
• An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye DiseaseRecruitingNCT07438405Phase 2
• AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid TumorsRecruitingNCT07403721Phase 1
• A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled GoutRecruitingNCT07388498Phase 3
• Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis ImperfectaRecruitingNCT07366086Phase 3
• Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)RecruitingNCT07297979Phase 1
• Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography TrialRecruitingNCT07293260Phase 3
• A Study Evaluating Subcutaneous Versus Intravenous Blinatumomab in Newly Diagnosed Adults With B-cell Precursor Acute Lymphoblastic LeukaemiaNot yet recruitingNCT07223190Phase 3
• Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Inebilizumab in Pediatric Participants With IgG4-RDNot yet recruitingNCT07222553Phase 2
• A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate CancerRecruitingNCT07213674Phase 3
• A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C MutationRecruitingNCT07172919Phase 2
• Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate CancerRecruitingNCT07140900Phase 1
• OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular EventsRecruitingNCT07136012Phase 3
• AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid TumorsRecruitingNCT07094113Phase 1
• Olpasiran Expanded Access ProgramAvailableNCT07079267
• A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)RecruitingNCT07037758Phase 1
• Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and ObesityRecruitingNCT07037459Phase 3
• Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or ObesityRecruitingNCT07037433Phase 3
• A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children With Generalized Myasthenia Gravis (gMG)RecruitingNCT06987539Phase 2
• A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)RecruitingNCT06747949Phase 3
• Evaluation of Neoadjuvant Xaluritamig in Localized Prostate CancerRecruitingNCT06613100Phase 1
• Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)RecruitingNCT06598306Phase 1
• A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune DiseasesRecruitingNCT06570798Phase 2
• Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C MutationRecruitingNCT06252649Phase 3
• Aimovig Pregnancy Exposure RegistryRecruitingNCT06150781
• A Study to Evaluate Avacopan in Participants With ANCA-associated VasculitisRecruitingNCT06072482Phase 4
• A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)RecruitingNCT05920356Phase 3
• Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During PregnancyRecruitingNCT05909761
• A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic ArthritisRecruitingNCT05767047Phase 3
• Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum DisorderRecruitingNCT05549258Phase 2
• Apremilast Pediatric Study in Children With Active Juvenile Psoriatic ArthritisRecruitingNCT04804553Phase 3
• Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's DiseaseRecruitingNCT04528082Phase 3
• Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate CancerRecruitingNCT04221542Phase 1
• A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving HemodialysisRecruitingNCT03969329Phase 3
• A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on HemodialysisRecruitingNCT03633708Phase 3
• Study to Investigate Intravenous Blinatumomab in Japanese Adult Participants With Newly Diagnosed Philadelphia-negative B-precursor Acute Lymphoblastic Leukemia (B-ALL)CompletedNCT06649006Phase 1Results posted
• Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Prior Lines of TreatmentActive, not recruitingNCT06502977Phase 2Results posted
• A Study of Avacopan in Participants With Normal Renal Function and Participants With End-Stage Renal Disease (ESRD)CompletedNCT06468826Phase 1Results posted
• A Study to Assess Bioavailability of Rocatinlimab (AMG 451) Vial and Prefilled Syringe in Healthy ParticipantsCompletedNCT06268860Phase 1Results posted
• A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory GoutCompletedNCT06229145Phase 4Results posted
• A Study of Romosozumab (EVENITY®) in Postmenopausal Women in India With Osteoporosis at a High Risk of Fracture.CompletedNCT06079476Phase 4Results posted
• A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)CompletedNCT05899816Phase 3Results posted
• Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung CancerActive, not recruitingNCT05740566Phase 3Results posted
• A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD)CompletedNCT05724199Phase 3Results posted
• A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)CompletedNCT05704738Phase 3Results posted
• A Study to Evaluate ABP 938 and Aflibercept (Eylea®) in Participants With Chorioretinal Vascular Disease (CVD)CompletedNCT05704725Phase 3Results posted
• A Phase 2 Proof of Concept Study to Evaluate the Efficacy and Safety of Daxdilimab in Participants With Dermatomyositis (DM) or Anti-synthetase Inflammatory Myositis (ASIM)CompletedNCT05669014Phase 2Results posted
• A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)CompletedNCT05651711Phase 3Results posted
• A Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)CompletedNCT05633355Phase 3Results posted
• An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc)TerminatedNCT05626751Phase 2Results posted
• Study of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN)TerminatedNCT05540665Phase 2Results posted
• A Study to Evaluate the Impact of Omeprazole on the Pharmacokinetics of Sotorasib Co-administered With an Acidic Beverage in Healthy VolunteersCompletedNCT05497557Phase 1Results posted
• Study of Daxdilimab (HZN-7734) for the Treatment of Systemic Lupus Erythematosus in an Open-label Extension StudyTerminatedNCT05430854Phase 2Results posted
• A Study Evaluating Rocatinlimab in Moderate-to-severe Atopic Dermatitis (ROCKET-IGNITE)CompletedNCT05398445Phase 3Results posted
• Study of DAXDILIMAB for the Treatment of Moderate-to-Severe Alopecia AreataCompletedNCT05368103Phase 2Results posted
• A Study in Healthy Volunteers to Compare the Pharmacokinetics of Sotorasib Administered as 1 or 2 TabletsCompletedNCT05327491Phase 1Results posted
• A Study of Bemarituzumab Monotherapy and Combination With Other Anti-cancer Therapy in SqNSCLC With FGFR2b Overexpression (FORTITUDE-201)TerminatedNCT05267470Phase 1Results posted
• AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic LeukemiaTerminatedNCT05209152Phase 1Results posted
• Sotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C MutationCompletedNCT05198934Phase 3Results posted
• Phase 3, Randomized Study of Apremilast in Japanese Participants With Palmoplantar Pustulosis (PPP)CompletedNCT05174065Phase 3Results posted
• A Comparative Study Between ABP 501 and Humira® in Participants With Moderate to Severe Plaque PsoriasisCompletedNCT05073315Phase 3Results posted
• Study of AMG 133 Administered Subcutaneously in Healthy Japanese and Caucasian ParticipantsCompletedNCT05056246Phase 1Results posted
• A Study to Compare the Pharmacokinetics of Two Different Tablets of Sotorasib in Healthy ParticipantsCompletedNCT05048784Phase 1Results posted
• Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy ParticipantsCompletedNCT05045638Phase 1Results posted
• A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary FibrosisTerminatedNCT05032066Phase 2Results posted
• Study of Efavaleukin Alfa in Healthy Chinese, Japanese, and Caucasian ParticipantsCompletedNCT04987333Phase 1Results posted
• A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Olpasiran in Chinese Participants With Elevated Serum Lipoprotein(a)CompletedNCT04987320Phase 1Results posted
• Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative ColitisTerminatedNCT04987307Phase 2Results posted
• A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line TreatmentTerminatedNCT04933695Phase 2Results posted
• Study of VIB7734 for the Treatment of Moderate to Severely Active SLECompletedNCT04925934Phase 2Results posted
• Pharmacokinetics of Sotorasib in Healthy Participants and Participants With Moderate or Severe Hepatic ImpairmentCompletedNCT04887064Phase 1Results posted
• AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)CompletedNCT04885998Phase 1Results posted
• Study to Evaluate Tezepelumab in Adults With Chronic Spontaneous UrticariaCompletedNCT04833855Phase 2Results posted
• A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With MigraineCompletedNCT04825678Phase 4Results posted
• Study of AMG 160 in Subjects With Non-Small Cell Lung CancerTerminatedNCT04822298Phase 1Results posted
• A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic SclerosisTerminatedNCT04781543Phase 2Results posted
• Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase MonotherapyCompletedNCT04772313Phase 4Results posted
• A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL)CompletedNCT04762498Phase 4Results posted
• A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque PsoriasisCompletedNCT04761627Phase 3Results posted
• A Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate CarcinomaTerminatedNCT04740034Phase 1Results posted
• Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid TumorsCompletedNCT04727554Phase 1Results posted
• A Study of AMG 757 in Participants With Neuroendocrine Prostate CancerCompletedNCT04702737Phase 1Results posted
• Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus ErythematosusTerminatedNCT04680637Phase 2Results posted
• Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)TerminatedNCT04631601Phase 1/2Results posted

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