Akebia Therapeutics: all 51 studies

Page 1 of 1. Open to participants first (3), then studies with results posted, then the rest; newest registration first within each.

• SAD and MAD Study of AKB-9090 in Healthy Adult ParticipantsRecruitingNCT07429006Phase 1
• A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)RecruitingNCT07268638Phase 2
• A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3GRecruitingNCT06419205Phase 2
• Study Evaluating the Efficacy and Safety of Dose Conversion From a Long-acting Erythropoiesis-stimulating Agent (Mircera®) to Three Times Weekly Oral Vadadustat for the Maintenance Treatment of Anemia in Hemodialysis SubjectsCompletedNCT04707768Phase 3Results posted
• Study to Assess the Safety and Pharmacokinetics of AKB-6548 in Participants With Chronic Kidney Disease (CKD), Stages 3 and 4CompletedNCT04707573Phase 2Results posted
• Trial Evaluating the Efficacy and Safety of Oral Vadadustat Once Daily (QD) and Three Times Weekly (TIW) for the Maintenance Treatment of Anemia in Hemodialysis Subjects Converting From Erythropoiesis-Stimulating Agents (ESAs)CompletedNCT04313153Phase 3Results posted
• Study of Vadadustat in Hemodialysis Participants With Anemia Switching From Epoetin AlfaCompletedNCT03799627Phase 2Results posted
• A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)CompletedNCT03254485Phase 2Results posted
• KRX-0502 (Ferric Citrate) in Subjects With NDD-CKD and IDA (The COMPASS Trial)CompletedNCT03236246Phase 4Results posted
• A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by AlbuminuriaCompletedNCT03217591Phase 2Results posted
• Study to Evaluate Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Who Are Hyporesponsive to Erythropoiesis Stimulating AgentsTerminatedNCT03140722Phase 2Results posted
• Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Dialysis-Dependent Chronic Kidney Disease (DD-CKD)CompletedNCT03054350Phase 2Results posted
• Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)CompletedNCT03054337Phase 2Results posted
• Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)CompletedNCT02892149Phase 3Results posted
• Efficacy and Safety Study to Evaluate Vadadustat for the Correction or Maintenance Treatment of Anemia in Participants With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD)CompletedNCT02865850Phase 3Results posted
• Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)CompletedNCT02680574Phase 3Results posted
• Study to Evaluate Vadadustat for the Correction of Anemia in Participants With Non-dialysis-dependent Chronic Kidney DiseaseCompletedNCT02648347Phase 3Results posted
• KRX-0502 (Ferric Citrate) for the Treatment of IDA in Adult Subjects With NDD-CKDCompletedNCT02268994Phase 3Results posted
• 16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requiring Chronic HemodialysisCompletedNCT02260193Phase 2Results posted
• A Pilot Study of KRX-0502 (Ferric Citrate, Administered Without Food, in Treating Iron-deficiency AnemiaCompletedNCT02128074Phase 2Results posted
• 20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and AnemiaCompletedNCT01906489Phase 2Results posted
• Ferric Citrate in Managing Serum Phosphorus and Iron Deficiency in Anemic Chronic Kidney Disease (CKD) Subjects Not on DialysisCompletedNCT01736397Phase 2Results posted
• A Long-Term Safety Extension Trial of Ferric Citrate in Patients With End-Stage Renal Disease (ESRD) on DialysisCompletedNCT01554982Phase 3Results posted
• 42-Day Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and AnemiaCompletedNCT01381094Phase 2Results posted
• Safety and Efficacy Study for AKB-6548 in Participants With Chronic Kidney Disease and AnemiaCompletedNCT01235936Phase 2Results posted
• A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on DialysisCompletedNCT01191255Phase 3Results posted
• A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal DiseaseCompletedNCT01074125Phase 3Results posted
• Trial of a New Formulation of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal DiseaseCompletedNCT00967993Results posted
• A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD)CompletedNCT00648167Phase 2Results posted
• Effect of Sulodexide in Early Diabetic NephropathyCompletedNCT00130208Phase 3Results posted
• To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center HemodialysisCompletedNCT06901505Phase 3
• Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease Naive to Erythropoiesis-Stimulating AgentsWithdrawnNCT05082584Phase 3
• Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney DiseaseWithdrawnNCT05082571Phase 3
• Study to Evaluate the Safety and Tolerability of KRX-0502 (Ferric Citrate) in Children With Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney DiseaseWithdrawnNCT04649411Phase 3
• Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney DiseaseSuspendedNCT04523727Phase 3
• Study in Healthy Adult Subjects to Assess the Effect of Phosphate Binders on the Pharmacokinetics of a Single Dose of VadadustatCompletedNCT04299633Phase 1
• Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Vadadustat in Hemodialysis Subjects With Anemia Associated With Chronic Kidney DiseaseCompletedNCT03992066Phase 1
• Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and FurosemideCompletedNCT03801759Phase 1
• Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and RifampinCompletedNCT03801746Phase 1
• Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and SimvastatinCompletedNCT03801733Phase 1
• A Single Dose Study of Oral Vadadustat in Subjects With Normal and Impaired Hepatic FunctionCompletedNCT03799848Phase 1
• Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of VadadustatCompletedNCT03789032Phase 1
• A Study in Evaluating Bioequivalence of Test and Reference Vadadustat 450 MG and 150 MG Tablets and to Determine Food Effect on the 450 MG TabletCompletedNCT03657290Phase 1
• A Study in Evaluating Bioequivalence Between Test and Reference Formulations of Vadadustat Tablets in Healthy AdultsCompletedNCT03639155Phase 1
• Study to Evaluate Three Times Per Week (TIW) Oral Dosing of Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD)WithdrawnNCT03242967Phase 3
• Effect of AKB-6548 on the Pharmacokinetics of CelecoxibCompletedNCT02502500Phase 1
• Relative Bioavailability of Two Formulations of AKB-6548 and the Food Effect of a New Tablet in Healthy Adult SubjectsCompletedNCT02412449Phase 1
• Effects of Ferrous Sulfate on the Pharmacokinetics of AKB-6548CompletedNCT02327546Phase 1
• Effect of AKB-6548 on Cardiac Repolarization Intervals in Healthy VolunteersCompletedNCT02062203Phase 1
• Open Label Tolerability and Safety Study of KRX-101 in Australia, New Zealand, and Hong KongTerminatedNCT00462202Phase 3
• Effect of Sulodexide in Overt Diabetic NephropathyTerminatedNCT00130312Phase 4

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