Abramson Cancer Center at Penn Medicine: Carcinoma, Non-Small-Cell Lung trials

The registry lists 23 Carcinoma, Non-Small-Cell Lung studies with Abramson Cancer Center at Penn Medicine as lead sponsor. 2 are open to participants now and 10 have results posted.

Phase 1 7Phase 2 10No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based TherapyRecruitingNCT04691817Phase 1/2
• Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab MaintenanceRecruitingNCT04332367Phase 2
• Binimetinib and Hydroxychloroquine in Patients With Advanced KRAS Mutant Non-Small Cell Lung CancerCompletedNCT04735068Phase 2Results posted
• Implementation Strategies for Monitoring Adherence in Real TimeActive, not recruitingNCT04347161Not applicableResults posted
• Trial of Consolidation Pembrolizumab After Concurrent Chemotherapy and Proton Reirradiation for Thoracic Recurrences of Non-Small Cell Lung CancerCompletedNCT03087760Phase 2Results posted
• The Detection Of Circulating Tumor Cells (CTC) In Patients With NSCLC Undergoing Definitive Radiotherapy Or ChemoradiotherapyCompletedNCT02135679Results posted
• Etirinotecan Pegol (NKTR-102) in NSCLCCompletedNCT01773109Phase 2Results posted
• Proton Beam Radiation With Concurrent Chemotherapy and Nelfinavir for Inoperable Stage III Non Small Cell Lung Cancer (NSCLC)TerminatedNCT01108666Phase 2Results posted
• Proton Beam Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Can Be Removed By SurgeryCompletedNCT01076231Phase 1/2Results posted
• Phase II Study of Sorafenib + Carboplatin and Docetaxel in First Line Treatment of Stage IIIB/IV NSCLCCompletedNCT00647426Phase 2Results posted
• Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the PleuraTerminatedNCT00601848Phase 2Results posted
• Nelfinavir, Radiation Therapy, Cisplatin, and Etoposide in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By SurgeryCompletedNCT00589056Phase 1/2Results posted
• Effects of Immune Checkpoint Inhibitors on Coronary MicrovasculatureActive, not recruitingNCT06332131
• Functional Lung Imaging With DECT and 4DCTCompletedNCT04702607
• A Prospective Study of Electronic Symptom Reporting Via Mobile Phone Among Patients With Advanced Non-Small Cell Lung CancerCompletedNCT03616522
• FDG PET/CT in Lung Cancer StagingCompletedNCT02738398Not applicable
• Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic CancersCompletedNCT02639026Phase 1
• Serial [18F]Fluorodeoxyglucose ([18F]FDG )PET/CT as a Biomarker of Therapeutic Response in Anti-PD1/PDL1 TherapyTerminatedNCT02608528
• Improving Clinical Trial Awareness in NSCLC: Pilot Testing A Novel Healthcare IT Platform for Incorporating Education at the Point of CareCompletedNCT02558998Not applicable
• The Utility of Circulating Tumor Cells as Confirmation of Pathologic Diagnosis in Patients With Suspected Early Stage Non-small Cell Lung CancerCompletedNCT02380196
• Fluorine F18-EF5 and Fludeoxyglucose F18 Positron Emission Tomography in Assessing Hypoxia and Glycolysis in Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung CancerCompletedNCT01017133Phase 1
• Flaxseed Supplement in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Undergoing Chemotherapy and Radiation TherapyTerminatedNCT00955942Phase 1
• Tipifarnib Plus Radiation Therapy After Combination Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung CancerCompletedNCT00025480Phase 1