AbbVie: Keratoconjunctivitis Sicca trials

The registry lists 35 Keratoconjunctivitis Sicca studies with AbbVie as lead sponsor. 0 are open to participants now and 32 have results posted.

Phase 1 3Phase 2 3Phase 3 11Phase 4 6No phase 13(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Assess Symptom Relief and Product Tolerability of ABBV-444 Drops in Adult ParticipantsCompletedNCT05878067Phase 3Results posted
• Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye DiseaseCompletedNCT04393441Phase 3Results posted
• A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye DiseaseCompletedNCT04030962Phase 1/2Results posted
• Goblet Cell Degranulation Produced by Intranasal Tear Neurostimulator (ITN) in Dry Eye DiseaseTerminatedNCT03827564Not applicableResults posted
• Optive Brand For Day And Night Dry Eye ManagementCompletedNCT03208673Not applicableResults posted
• Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry EyeTerminatedNCT02965846Phase 3Results posted
• Evaluation of Dry Eye Symptoms in CAE With Application of Intranasal NeurostimulationCompletedNCT02910713Not applicableResults posted
• Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry EyeTerminatedNCT02815293Phase 3Results posted
• A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease.CompletedNCT02553772Phase 3Results posted
• A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye ReliefCompletedNCT02455050Phase 3Results posted
• Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye DiseaseCompletedNCT02435914Phase 2Results posted
• Evaluation of the Safety and Effectiveness of the Oculeve Intranasal Lacrimal Neurostimulator in Patients With Dry EyeCompletedNCT02313454Not applicableResults posted
• A Safety and Efficacy Study of Refresh Optive® Gel Drops in Patients With Dry Eye DiseaseCompletedNCT02280473Phase 3Results posted
• A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry EyeCompletedNCT02117687Phase 4Results posted
• A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye SymptomsCompletedNCT02028754Phase 4Results posted
• Phase 2 Study of a New Ophthalmic Formulation of Cyclosporine (Restasis® X) in Patients With Dry Eye DiseaseTerminatedNCT02013791Phase 2Results posted
• A Study to Determine the Prevalence of Inflammatory Dry Eye Disease in Patients Prior to Cataract RemovalCompletedNCT01882413Results posted
• An Observational Study of Dry Eye Prior to Laser-Assisted in Situ Keratomileusis (LASIK) TherapyCompletedNCT01854905Results posted
• An Observational Study of OPTIVE PLUS® for the Treatment of Dry Eye DiseaseCompletedNCT01711424Results posted
• Safety and Efficacy of Punctal Plug Insertion in Patients With Dry EyeCompletedNCT01684436Phase 4Results posted
• A Study to Compare the Safety and Efficacy of A New Eye Drop Formulation With OPTIVE™ in Subjects With Dry Eye DiseaseCompletedNCT01664949Phase 3Results posted
• Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye DiseaseCompletedNCT01459588Phase 3Results posted
• Study of Two Formulations of Cyclosporine Ophthalmic Emulsion in Healthy Volunteers and in Patients With Dry EyeCompletedNCT01319773Phase 1Results posted
• Safety and Efficacy Study of New Eye Drop Formulations With Refresh Tears® in Patients With Dry Eye DiseaseCompletedNCT01294384Phase 3Results posted
• Effects of Cataract Extraction Surgery and Limbal Relaxing Incision on Corneal Sensation and Dry EyeCompletedNCT01161771Results posted
• Safety and Efficacy of Two Artificial Tears in Dry Eye SubjectsCompletedNCT01010282Not applicableResults posted
• Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry EyeCompletedNCT00987727Phase 4Results posted
• Study to Compare the Efficacy and Safety of Two Non-Preserved Artificial Tears for the Treatment of Dry Eye Signs and SymptomsCompletedNCT00938704Phase 4Results posted
• Safety and Tolerability of Artificial Tears in Dry Eye SubjectsCompletedNCT00932477Not applicableResults posted
• Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye SymptomsCompletedNCT00761202Phase 4Results posted
• Efficacy Study of Cyclosporine Ophthalmic Emulsion in Patients With Dry Eye DiseaseCompletedNCT00717418Results posted
• Safety and Efficacy of an Artificial Tear for the Treatment of Dry EyeCompletedNCT00514852Not applicableResults posted
• Safety, Tolerability and Systemic Pharmacokinetics of AGN-232411 in Healthy Participants and Participants With Dry EyeCompletedNCT02420730Phase 1
• A Natural History Study of Patients With Dry EyeCompletedNCT00833235
• Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye SyndromeCompletedNCT00025818Phase 3