Vandetanib: all 99 studies that test it
Page 1 of 1. Open to participants first (1), then studies with results posted, then the rest; newest registration first within each.
- Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid CancerRecruitingNCT06482086Phase 2
- Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid CancerTerminatedNCT03630120Phase 2Results posted
- Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell CarcinomaTerminatedNCT02495103Phase 1/2Results posted
- Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal TumorsCompletedNCT02015065Phase 2Results posted
- Effect of Vandetanib on Cellular Markers in Invasive Breast CancerTerminatedNCT01934335Phase 2Results posted
- Evaluation of Efficacy, Safety of Vandetanib in Patients With Differentiated Thyroid CancerCompletedNCT01876784Phase 3Results posted
- Evaluate the Safety and Tolerability of Vandetanib in Japanese Patients With Medullary Thyroid CarcinomaCompletedNCT01661179Phase 1/2Results posted
- A Phase I Trial of Vandetanib (AZD6474) and Selumetinib (AZD6244) for Solid Tumours Including Non Small Cell Lung Cancer (VanSel-1)CompletedNCT01586624Phase 1Results posted
- Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic CancerCompletedNCT01582191Phase 1Results posted
- To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid CancerCompletedNCT01496313Phase 4Results posted
- Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck LesionsCompletedNCT01414426Phase 2Results posted
- Vandetanib to Treat Advanced Kidney CancerTerminatedNCT01372813Phase 2Results posted
- A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by SurgeryCompletedNCT01183559Phase 1Results posted
- A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade GliomasCompletedNCT00995007Phase 2Results posted
- Randomized Study of Docetaxel +/- Vandetanib in Metastatic TCCCompletedNCT00880334Phase 2Results posted
- S0904: Docetaxel With or Without Vandetanib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal CancerCompletedNCT00872989Phase 2Results posted
- Addition of Vandetanib to Standard Therapy Pegliposomal Doxorubicin (PLD)TerminatedNCT00862836Phase 1/2Results posted
- Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Following Platinum-doublet ChemotherapyCompletedNCT00777179Phase 2Results posted
- Zactima in Non Small Cell Lung Cancer (NSCLC) ELderly Patients In Combination With or Versus GemcitabineCompletedNCT00753714Phase 2Results posted
- Vandetanib Gemcitabine Or Placebo Plus Gemcitabine Or Vandetanib Monotherapy In Advanced Biliary Tract CancerCompletedNCT00753675Phase 2Results posted
- ZACtima FASlodex Trial in Postmenopausal Advance Breast Cancer Patients Instead of ZACtima FASlodex TrialTerminatedNCT00752986Phase 2Results posted
- Chemotherapy and Radiation Therapy (RT) With or Without Vandetanib in Treating Patients With High-Risk Stage III or Stage IV Head and Neck CancerTerminatedNCT00720083Phase 2Results posted
- Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung CancerCompletedNCT00687297Phase 2Results posted
- Trial Assessing Zactima Against Placebo in Prostate Cancer Subjects Undergoing Intermittent Androgen Deprivation Hormonal TherapyTerminatedNCT00686036Phase 2Results posted
- Docetaxel With or Without Vandetanib in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction CancerTerminatedNCT00683787Phase 2Results posted
- Efficacy and Safety of Zactima™ in Patients With Castration-refractory Metastatic Prostate CancerCompletedNCT00659438Phase 2Results posted
- Cisplatin + Etoposide +/- Concurrent ZD6474 in Previously Untreated Extensive Stage Small Cell Lung CancerCompletedNCT00613626Phase 2Results posted
- An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant MesotheliomaTerminatedNCT00597116Phase 2Results posted
- Phase II Study of Vandetanib in Individuals With Kidney CancerCompletedNCT00566995Phase 2Results posted
- Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid CancerCompletedNCT00537095Phase 2Results posted
- Vandetanib to Treat Children and Adolescents With Medullary Thyroid CancerCompletedNCT00514046Phase 1/2Results posted
- Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular Carcinoma (HCC)CompletedNCT00508001Phase 2Results posted
- A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatment of Colorectal CancerCompletedNCT00500292Phase 2Results posted
- E3 Breast Cancer Taxotere CombinationCompletedNCT00494481Phase 2Results posted
- Phase 2 Anastrozole and Vandetanib (ZD6474) in Neoadjuvant Treatment of Postmenopausal Hormone Receptor-Positive Breast CancerTerminatedNCT00481845Phase 2Results posted
- Vandetanib, Carboplatin, and Paclitaxel in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer That Can Be Removed by SurgeryTerminatedNCT00459121Phase 2Results posted
- Docetaxel in Combination With Zactima (ZD6474) in Patients With Locally Advanced Squamous Cell Carcinoma of the the Head and NeckCompletedNCT00459043Phase 2Results posted
- A Phase II, Double Blind Study of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in PatientsCompletedNCT00454116Phase 2Results posted
- Vandetanib to Treat Women With Ovarian, Fallopian Tube, or Primary Peritoneal CancerTerminatedNCT00445549Phase 2Results posted
- Zactima With Temodar During Radiation Treatment for Newly Diagnosed Stage IV Brain TumorsCompletedNCT00441142Phase 1/2Results posted
- Efficacy Study Comparing ZD6474 in Combination With Pemetrexed and Pemetrexed Alone in 2nd Line NSCLC PatientsCompletedNCT00418886Phase 3Results posted
- An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid CancerCompletedNCT00410761Phase 3Results posted
- BATTLE Program: ZD6474 in Previously Treated Subjects With NSCLCCompletedNCT00410189Phase 2Results posted
- ZD6474 (ZACTIMA™) Phase III Study in EGFR FailuresCompletedNCT00404924Phase 3Results posted
- Malignant Pleural Effusion With ZD6474TerminatedNCT00402896Phase 2Results posted
- Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior ChemotherapyCompletedNCT00364351Phase 3Results posted
- A Study To Assess ZD6474 (ZACTIMA™) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid CancerCompletedNCT00358956Phase 2Results posted
- ZACTIMA (an Anti-EGFR / Anti-VEGF Agent) Combined With Docetaxel Compared to Docetaxel in Non-small Cell Lung CancerCompletedNCT00312377Phase 3Results posted
- Efficacy and Tolerability of ZD6474 in Patients With Thyroid CancerCompletedNCT00098345Phase 2Results posted
- Genomics-Based Target Therapy for Children With Relapsed or Refractory MalignancyStatus unknownNCT02638428Phase 2
- Fulvestrant +/- Vandetanib in Advanced Aromatase Inhibitor Resistant Breast CancerStatus unknownNCT02530411Phase 2
- SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast CancerActive, not recruitingNCT02299999Phase 2
- HGG-TCP (High Grade Glioma - Tumor Concentrations of Protein Kinase Inhibitors)Status unknownNCT02239952Not applicable
- SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC PatientsCompletedNCT02117167Phase 2
- A Pilot Study of Genomic Sequencing Guided Individualized Therapy in Gastrointestinal Cancers, GITIC StudyStatus unknownNCT02013089Not applicable
- Phase I Trial of Vandetanib Combined With 131I-mIBG to Treat Patients With Advanced Phaeochromocytoma and ParagangliomaWithdrawnNCT01941849Phase 1
- Vandetanib in Advanced NSCLC With RET RearrangementCompletedNCT01823068Phase 2
- Clinical Trial Comparing Gemcitabine and Vandetanib Therapy With Gemcitabine Alone in Pancreatic CarcinomaCompletedNCT01601808Phase 2
- Study in Healthy Volunteers to Assess the Pharmacokinetics (PK) of Digoxin Administered Alone and in Combination With VandetanibCompletedNCT01561781Phase 1
- A Phase I Study to Assess the Pharmacokinetics of Metformin When Administered Alone and in Combination With VandetanibCompletedNCT01551615Phase 1
- Study in Healthy Volunteers to Assess the Pharmacokinetics of Midazolam Administered Alone and in Combination With VandetanibCompletedNCT01544140Phase 1
- Study in Healthy Volunteers to Assess Effect of Omeprazole and Ranitidine on the Pharmacokinetics of VandetanibCompletedNCT01539655Phase 1
- Carboplatin and Gemcitabine Hydrochloride With or Without Vandetanib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urinary Tract CancerCompletedNCT01191892Phase 2
- Trial of ZD6474 and Faslodex in Non-Small Cell Lung CancerWithdrawnNCT01004419Phase 1
- Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)CompletedNCT00996723Phase 1
- S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid TumorsWithdrawnNCT00937417Phase 1
- Dose Escalation Study of Vandetanib With Hypofractionated Stereotactic Radiotherapy in Recurrent Malignant GliomasCompletedNCT00822887Phase 1
- Vandetanib and Sirolimus in Patients With Recurrent GlioblastomaCompletedNCT00821080Phase 1
- Trial to Evaluate the Therapeutic Benefit of Fulvestrant in Combination With ZACTIMA in Postmenopausal Women With Bone Predominant, Hormone Receptor Positive Metastatic Breast CancerCompletedNCT00811369Phase 2
- Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain MetastasesTerminatedNCT00807170Phase 1
- Efficacy and Safety Study of Vandetanib (ZD 6474) in Combination With Bicalutamide Versus Bicalutamide Alone in Patients With Chemotherapy Naive Hormone Refractory Prostate Cancer.CompletedNCT00757692Phase 2
- Radiation Therapy (XRT) and ZD6474 in Non-Small Cell Lung Cancer (NSCLC)TerminatedNCT00745732Phase 1
- Vandetanib and Bevacizumab in Treating Patients With Advanced Solid Tumors or LymphomaCompletedNCT00734890Phase 1
- Vandetanib, Oxaliplatin, and Docetaxel in Advanced Cancer of the Esophagus or Gastroesophageal JunctionTerminatedNCT00732745Phase 1
- Dose Escalation Study With Zactima and Chemotherapy in Metastatic Pancreas CarcinomaCompletedNCT00681798Phase 1
- Study of GemOx and Vandetanib in Advanced Solid MalignancyCompletedNCT00660725Phase 1
- Ph I Dose Escalation Trial of Vandetanib in Combo w Etoposide for Malignant GliomasCompletedNCT00613223Phase 1
- Ph I Zactima + Imatinib Mesylate & Hydroxyurea for Pts w Recurrent Malignant GliomaCompletedNCT00613054Phase 1
- Vandetanib and Temozolomide in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By SurgeryWithdrawnNCT00601614Phase 1
- Gemcitabine/Capecitabine/ZD6474 in Advanced Solid TumorsCompletedNCT00551096Phase 1
- ZD6474 Alone and in Combination With Retinoic Acid in Pediatric NeuroblastomaTerminatedNCT00533169Phase 1
- Phase I Vandetanib Plus Capecitabine, Oxaliplatin and Bevacizumab for Metastatic Colorectal CancerCompletedNCT00532909Phase 1
- Phase I Irinotecan, 5-Fluorouracil and Leucovorin CombinationCompletedNCT00507091Phase 1
- ZD6474(Vandetanib) + Alimta Combo StudyCompletedNCT00506051Phase 1
- Phase I Chinese PKCompletedNCT00503711Phase 1
- Phase I FOLFOX CombinationCompletedNCT00499850Phase 1
- ZD6474 (Zactima) and Metronomic Chemotherapy in Advanced Breast CancerCompletedNCT00496665Phase 1
- Phase I Efficacy On Vascular Permeability In Patients With Advanced Colorectal CancerCompletedNCT00496509Phase 1
- Phase I Combination With Vinorelbine or Gemcitabine Plus Cisplatin in Locally Advanced or Metastatic NSCLCCompletedNCT00496275Phase 1
- Vandetanib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Diffuse Brainstem GliomaCompletedNCT00472017Phase 1
- ZD6474, Cetuximab, and Irinotecan in Patients With Metastatic Colorectal CancerCompletedNCT00436072Phase 1
- ZD6474 to Treat Advanced Brain Cancer in PatientsCompletedNCT00272350Phase 1
- ZD6474 Phase IIa Dose Finding Multicentre StudyCompletedNCT00252746Phase 2
- ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)CompletedNCT00071188Phase 2
- ZD6474 in Treating Patients With Small Cell Lung CancerCompletedNCT00066313Phase 2
- This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.CompletedNCT00059722Phase 2
- This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer.CompletedNCT00047840Phase 2
- Efficacy Study of ZD6474 to Treat Multiple Myeloma CancerCompletedNCT00047788Phase 2
- This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Metastatic Breast CancerCompletedNCT00034918Phase 2