Tyrosine Kinase Inhibitors: all 10,469 studies that test it
Page 52 of 105. Open to participants first (1,907), then studies with results posted, then the rest; newest registration first within each.
- Retinol Binding Protein 4 Protein in Alopecia Areata Treated With BarcitinibActive, not recruitingNCT06545110Phase 1
- Phase I Study Evaluating Tolerability, Safety, Pharmacokinetics, and Efficacy of Combined ONO-4059 and R-MPV Therapy for PCNSLActive, not recruitingNCT06541665Phase 1
- DZD8586 in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (TAI-SHAN9)CompletedNCT06539195Phase 2
- A PhaseⅠStudy of ONO-7475 in Combination With ONO-4538 and Gemcitabine Plus Nab-paclitaxel (GnP), the Standard of Care, and ONO-7475 in Combination With GnP in Patients With Pancreatic CancerActive, not recruitingNCT06532331Phase 1
- Deucravacitinib RosaceaWithdrawnNCT06532136Phase 2
- Food Effect and Relative Bioavailability Study of VC004 Capsules in Healthy Adult SubjectsCompletedNCT06529445Phase 1
- Study of ONO-7475 in Combination With Osimertinib in EGFR Gene Mutation-positive Non-small Cell Lung CancerCompletedNCT06525246Phase 1
- GATE1: A Multicenter Phase II Study of Pirtobrutinib, Rituximab and Venetoclax Combination Therapy for Patients With Previously Untreated Mantle Cell LymphomaActive, not recruitingNCT06522386Phase 2
- Brigatinib Plus Chemotherapy or Local Consolidation Therapy in ALK Positive Advanced Non-small Cell Lung Cancer (BrightStar-2)WithdrawnNCT06522360Phase 2
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled AZD4604 in Healthy Japanese and Chinese Participants.CompletedNCT06519968Phase 1
- A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)Active, not recruitingNCT06516965Phase 3
- A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)Active, not recruitingNCT06516952Phase 3
- Study of Bemcentinib Plus Pacritinib In Patients With Advanced Lung AdenocarcinomaTerminatedNCT06516887Phase 1/2
- AZD4205 in Relapsed or Refractory Peripheral T Cell Lymphoma (JACKPOT27)CompletedNCT06511895Phase 2
- AZD4205 in Peripheral T Cell Lymphoma Following First-Line Therapy (JACKPOT26)CompletedNCT06511869Phase 2
- A Clinical Study to Evaluate the Tolerance, Pharmacokinetics and Efficacy of TQ-A3334 TabletsTerminatedNCT06507891Phase 1/2
- Futibatinib in Patients Previously Enrolled in an Antecedent Futibatinib as Monotherapy or Combination Therapy.Active, not recruitingNCT06506955Phase 2/3
- A Study to Evaluate Skin and Plasma Pharmacokinetic of Multiple Doses of Povorcitinib After Oral Administration in Healthy ParticipantsCompletedNCT06505265Phase 1
- Obinutuzumab, Zanubrutinib, and Lenalidomide Followed Short-Cycle of Obinutuzumab and Cytarabine in Newly Diagnosed Mantle Cell LymphomaActive, not recruitingNCT06504199Phase 2
- A Study of BL-B01D1 in Combination With Osimertinib Mesylate Tablets in Patients With Locally Advanced or Metastatic Non-small Cell Lung CancerActive, not recruitingNCT06498986Phase 2
- Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular DegenerationActive, not recruitingNCT06495918Phase 3
- Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous CarcinomaCompletedNCT06494189Phase 1
- A Study to Assess the Effect of Voriconazole and Quinidine on the Pharmacokinetics of a Single Dose of Repotrectinib in Healthy ParticipantsCompletedNCT06493409Phase 1
- Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With HemoblastosisActive, not recruitingNCT06475820Phase 2/3
- A Phase I Study Investigating the Combination of Cladribine, Low Dose Cytarabine and Sorafenib Alternating With Decitabine in Pediatric Relapsed and Refractory Acute LeukemiasWithdrawnNCT06474663Phase 1
- Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV Steroid-refractory Acute Graft vs. Host DiseaseActive, not recruitingNCT06462469Phase 4
- A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic DermatitisActive, not recruitingNCT06461897Phase 3
- Clinical Trial to Investigate the Effects of Food on the Pharmacokinetics and Safety of Orally Administered RadotinibCompletedNCT06461078Phase 1
- Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid LeukemiaSuspendedNCT06454409Phase 1
- Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction AdenocarcinomaActive, not recruitingNCT06447636Phase 2
- Apatinib Combined With cdk4/6i in First-line Treatment for HR+/HER2- SNF4 Subtype Breast CancerActive, not recruitingNCT06447623Phase 3
- Phase I Study of Q702 With Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid LeukemiaActive, not recruitingNCT06445907Phase 1
- A Study to Evaluate the Effect of Mild and Moderate Hepatic Impairment on the Single-Dose Pharmacokinetics of Rilzabrutinib (PRN1008)CompletedNCT06444204Phase 1
- Pharmacokinetics (PK) of Rilzabrutinib (PRN1008) in Healthy Japanese and Caucasian SubjectsCompletedNCT06444191Phase 1
- A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)CompletedNCT06442436Phase 1
- A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy ParticipantsCompletedNCT06441318Phase 1
- TGRX-326 Pharmacokinetic Mass BalanceCompletedNCT06438367Phase 1
- Phase II Study to Evaluate the Effect of AZD4604 on Airway Inflammation and Biomarkers in Adults With AsthmaCompletedNCT06435273Phase 2
- A 12-Week Open-Label Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Skin-Predominant DermatomyositisCompletedNCT06433999Phase 2
- Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I MutationCompletedNCT06427811Phase 4
- Fruquintinib Plus S-1 and Raltitrexed (RSF) for MCRCStatus unknownNCT06427005Phase 2
- Safety, Tolerability, Pharmacokinetics and Immunogenicity Study of GB002 Recombinant Peptide Inhalation Solution in Healthy SubjectsActive, not recruitingNCT06423261Phase 1
- A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung CancerActive, not recruitingNCT06417814Phase 3
- Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)TerminatedNCT06408168Phase 2
- RVU120 in Patients With Intermediate or High-risk, Primary or Secondary MyelofibrosisTerminatedNCT06397313Phase 2
- The Efficacy and Safety of Tislelizumab Combined With Anlotinib and S1 Plus Oxaliplatin as Neoadjuvant Therapy for the Locally Advanced Adenocarcinoma of Esophagogastric JunctionStatus unknownNCT06396585Phase 2
- The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related MyocarditisCompletedNCT06393972Phase 2
- JMT101 Combined With Osimertinib in Patients With Stage Ⅲb-Ⅳ Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Common MutationsActive, not recruitingNCT06391944Phase 2
- A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic DermatitisWithdrawnNCT06390722Phase 3
- A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to DupilumabActive, not recruitingNCT06389136Phase 3
- TQ05105 Tablet for Myelofibrosis Treatment in Ruxolitinib-Resistant or Intolerant PatientsTerminatedNCT06388759Phase 1
- A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host DiseaseActive, not recruitingNCT06388564Phase 2
- A Phase I Clinical Study of Flonoltinib Maleate Tablets in Healthy SubjectsCompletedNCT06387966Phase 1
- A Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult FemalesCompletedNCT06380205Phase 1
- A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy ParticipantsCompletedNCT06378658Phase 1
- Cabozantinib Treatment Prior to Cytoreductive Nephrectomy in Patients With Advanced or Metastatic Renal Cells CancerTerminatedNCT06377722Phase 2
- A Food Effect Study of SPH5030 Tablets.CompletedNCT06372223Phase 1
- A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.Active, not recruitingNCT06372145Phase 3
- A Study to Learn About How Different Forms of the Study Medicine Called Ritlecitinib Pass the Intestines of Healthy Male Adults When Taken With or Without FoodCompletedNCT06369454Phase 1
- Second-line Treatment With CAdonilimab and LEnvatinib for Unresectable HCCWithdrawnNCT06361758Phase 2
- A Study to Learn About How BAY2927088 Affects the Level of Midazolam in the Blood When Both Drugs Are Taken Together in Healthy ParticipantsCompletedNCT06360211Phase 1
- Tislelizumab With Fruquintinib, Metronidazole, in Mismatch Repair-proficient or Microsatellite Stability, Advanced Colorectal Cancer: a Multicenter, Single Arm, Clinical TrialActive, not recruitingNCT06356597Phase 2
- Alectinib in Combination With Nivolumab in the Treatment of Recurrent or Refractory HCC Patients Guided With Serum RNase1 and Tumor Expression of PD-L1CompletedNCT06354387Phase 1
- A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic ImpairmentCompletedNCT06352528Phase 1
- ZAP-IT: ZN-c3 + Carboplatin + Pembrolizumab in mTNBCTerminatedNCT06351332Phase 1
- A Positron-emission Tomography Study to Determine Brain Exposure of [11C]Savolitinib in Healthy VolunteersCompletedNCT06348355Phase 1
- Safety, Tolerability, and Preliminary Efficacy of Soquelitinib in Participants With Moderate to Severe ADCompletedNCT06345404Phase 1
- A Food Effect and Relative Bioavailability Study of Rilzabrutinib in Healthy ParticipantsCompletedNCT06342700Phase 1
- Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With OsteosarcomaTerminatedNCT06341712Phase 2
- A Study to Learn How Safe and Effective Risankizumab is When Compared to Deucravacitinib to Treat Participants With Moderate Plaque Psoriasis and Who Need to Try Systemic Treatment (Works Throughout the Whole Body)CompletedNCT06333860Phase 4
- Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's DiseaseActive, not recruitingNCT06332534Phase 3
- A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy ParticipantsCompletedNCT06329895Phase 1
- Combination of Sotyktu and Enstilar for Plaque PsoriasisCompletedNCT06329258Phase 4
- ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast CancerActive, not recruitingNCT06328738Phase 1
- Erdafitinib in Metastatic Steroid-cell Ovarian CancerCompletedNCT06328491Not applicable
- A Study to Evaluate ANS014004 in Subjects With Locally Advanced or Metastatic Solid TumorsActive, not recruitingNCT06328439Phase 1
- Vitiligo Treatment by Targeting TYK2 Mediated ResponsesActive, not recruitingNCT06327321Phase 2
- A Study of TAK-279 in Adult Participants With Generalized Pustular Psoriasis or Erythrodermic PsoriasisCompletedNCT06323356Phase 3
- A Clinical Trial to Evaluate a High-Fat Meal and Omeprazole Enteric-coated Tablets on ASBK021CompletedNCT06322706Phase 1
- Study of Pembrolizumab Plus Chemotherapy With Lenvatinib for Malignant Pleural MesotheliomaActive, not recruitingNCT06318286Phase 2
- A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative NeoplasmsActive, not recruitingNCT06313593Phase 1
- A Study to Evaluate the Relative Bioavailability of Ruxolitinib Extended Release (XR) Tablets Compared With Ruxolitinib Immediate Release (IR) Tablets Administered Orally in Healthy Participants.CompletedNCT06310304Phase 1
- Tofacitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Dose Escalation StudyCompletedNCT06310057Phase 4
- Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell CarcinomaActive, not recruitingNCT06308913Early Phase 1
- A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory NeuroblastomaWithdrawnNCT06308575Phase 2
- Pemigatinib in Patients With Relapsed or Refractory B-cell Non-Hodgkin LymphomasActive, not recruitingNCT06300528Phase 2
- Neoadjuvant Almonertinib Followed by Chemo-immunotherapy in II-IIIB EGFR-mutant NSCLCActive, not recruitingNCT06300424Phase 2
- A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)CompletedNCT06295432Phase 2
- TGRX-326 Pharmacokinetic Drug InteractionCompletedNCT06294561Phase 1
- The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)WithdrawnNCT06291415Phase 1
- A Study of the Interaction of Other Drugs With TAK-279 in Healthy AdultsCompletedNCT06290050Phase 1
- Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid TherapyCompletedNCT06283550Phase 2
- Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal MetastasesActive, not recruitingNCT06282874Phase 4
- Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell CarcinomaCompletedNCT06281886Phase 2
- TYK2 Inhibition in Paradoxical PsoriasisTerminatedNCT06281106Phase 2/3
- Upfront Immune Checkpoint Inhibitors With Deferred Cytoreductive Nephrectomy for Metastatic Renal Cell CarcinomaActive, not recruitingNCT06279403Phase 2
- A Clinical Study of AL2846 Capsule Combined With Gemzar Injection in the Treatment of Advanced Pancreatic CancerCompletedNCT06278493Phase 1/2
- Efficacy of Oral Tofacitinib in Moderate to Severe Alopecia Areata, Totalis and Universalis at Tertiary Care Hospital, Karachi.CompletedNCT06278402Phase 3
- A Phase 3 Study of LNK01001 Capsule in Subjects With Moderate to Severe Atopic Dermatitis.CompletedNCT06277245Phase 3
- A Study of LNK01001 Capsule in Subjects With Active Rheumatoid Arthritis (COURAGE-RA)Active, not recruitingNCT06276998Phase 3