Tyrosine Kinase Inhibitors: all 10,469 studies that test it
Page 5 of 105. Open to participants first (1,909), then studies with results posted, then the rest; newest registration first within each.
- Clinical Efficacy of Adebrelimab With or Without Apatinib Mesilate and SOX Neoadjuvant Therapy in Locally Advanced Gastric CancerNot yet recruitingNCT07314203Phase 3
- Ivarmacitinib in Advanced Solid Tumors: A Prospective, Two-Cohort, Two-Phase Exploratory Study in Patients Discontinued Due to Immune IntoleranceNot yet recruitingNCT07313202Phase 2
- Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic LeukemiaRecruitingNCT07311746Phase 1/2
- SHR-1701 + Rivoceranib (± SHR-2554) in Advanced GC After First-Line Immunotherapy FailureRecruitingNCT07311408Phase 2
- A Phase II Study of Anlotinib and Platinum-Based Chemotherapy in Patients With SMARCA4-Deficient, Locally Advanced or Metastatic Lung Cancer.Not yet recruitingNCT07307443Phase 2
- Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal MetastasesRecruitingNCT07304739Phase 2
- Golidocitinib for Refractory Immune-related Hematologic Toxicities of Advanced Lung CancerNot yet recruitingNCT07303881Phase 2
- Golidocitinib Versus Placebo as Maintenance Therapy for Peripheral T-Cell LymphomaRecruitingNCT07300514Phase 3
- Zanubrutinib, Obinutuzumab Combined With Lenalidomide (ZGR) for the Treatment of Untreated Follicular LymphomaRecruitingNCT07299149Phase 2
- A Study of Orelabrutinib in Patients With Secondary Progressive Multiple SclerosisRecruitingNCT07299019Phase 3
- Firmonertinib 160 mg in Patients With EGFR-Mutant Advanced NSCLC Demonstrating SD After 8 Week Induction With Firmonertinib 80 mgNot yet recruitingNCT07298148Phase 2
- Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALLRecruitingNCT07297914Phase 2/3
- First-Line Lenvatinib in Child-Pugh B Patients With HCC Unsuitable for Curative TreatmentNot yet recruitingNCT07297654Phase 2
- Safety and Efficacy of the JAK1 Inhibitor Combined With Intensive Immunosuppressive Therapy in Severe Aplastic AnemiaNot yet recruitingNCT07297550Phase 1/2
- Combination Therapy With Infliximab and Tofacitinib for Acute Severe Ulcerative Colitis - CINTO TrialNot yet recruitingNCT07297069Phase 2
- Osimertinib Induction and Maintenance for Chemo-ineligible Stage III Unresectable EGFR+ NSCLC: Single-arm StudyRecruitingNCT07295821Phase 2
- A Study of DZD8586 in Adults With Primary Immune Thrombocytopenia (ITP) (TAI-SHAN11)RecruitingNCT07294365Phase 2
- Garsorasib In KRAS G12C Mutant Locally Advanced and Metastatic NSCLCNot yet recruitingNCT07294261Phase 2
- Pembrolizumab Plus Lenvatinib in Vulvar Cancer Patients: MITO VULVA-01RecruitingNCT07290894Phase 2
- Continuation Study of Zasocitinib in Adults With Psoriatic ArthritisRecruitingNCT07286058Phase 3
- Clinical Trial to Evaluate the Efficacy and Safety of Pirtobrutinib With Rituximab in Patients With Mantle Cell LymphomaRecruitingNCT07285590Phase 2
- A Study to Evaluate ANS014004 in Combination With EGFR-TKI in Non-Small Cell Lung CancerNot yet recruitingNCT07285148Phase 1/2
- Amping up With PemJAKRecruitingNCT07283822Phase 2
- Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue SarcomaRecruitingNCT07283731Phase 2
- Pharmacokinetics of Olverembatinib in Participants With Hepatic ImpairmentRecruitingNCT07282093Phase 1
- Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren DiseaseRecruitingNCT07281456Phase 2
- Deucravacitinib-TNFi Combination Therapy for Difficult-to-Control Psoriatic DiseaseRecruitingNCT07280702Phase 4
- Justification And Evaluation of Baricitinib Plus Corticosteroids Versus corticosteroiDs Alone in pOlymyalgia RhEumaticaRecruitingNCT07279688Phase 3
- Golidocitinib Combined With GemOx in RR PTCLNot yet recruitingNCT07279584Phase 2
- Clinical Study of Adjuvant Surufatinib Therapy for Postoperative High-risk Neuroendocrine Tumors Based on the Ninth Edition of the AJCC Staging SystemNot yet recruitingNCT07279532Phase 2
- Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell LymphomasRecruitingNCT07278856Phase 1
- A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic LeukemiaRecruitingNCT07277231Phase 3
- Treatment of Moderate-to-Severe Atopic Dermatitis With Ivarmacitinib in Adolescents and AdultsNot yet recruitingNCT07276620Not applicable
- Prospective Multicenter Real-world Study of Surufatinib in Patients With Advanced Neuroendocrine NeoplasmsRecruitingNCT07272512Phase 4
- Orelabrutinib Plus Lisaftoclax and Rituximab in Untreated Mantle Cell Lymphoma With High-Risk DiseaseRecruitingNCT07272499Phase 2
- Trifluridine/Tipiracil + Fruquintinib Versus Trifluridine/Tipiracil Alone for Metastatic Oeso-gastric AdenocarcinomaRecruitingNCT07270991Phase 3
- Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell LymphomaRecruitingNCT07270835Phase 4
- Senolytics for Secondary Progressive MSNot yet recruitingNCT07270120Phase 1
- A Prospective, Single-arm, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Ivarmacitinib in the Treatment of Palmoplantar PustulosisRecruitingNCT07270003Not applicable
- Golcadomide, Poseltinib, and Rituximab for Relapsed/Refractory Diffuse Large B-cell LymphomaNot yet recruitingNCT07269639Phase 1/2
- Phase II Study Assessing the Safety and Efficacy of Dasatinib in Combination With Ropeginterferon in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic PhaseRecruitingNCT07269470Phase 2
- Biologics in Folliculitis Decalvans : an Adaptative Trial ResearchNot yet recruitingNCT07268534Phase 2
- Efficacy and Safety of Ivarmacitinib in the Treatment of Patients With Polymyalgia RheumaticaNot yet recruitingNCT07266168Not applicable
- Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial CarcinomaRecruitingNCT07265947Phase 2
- Sorafenib Combined With Venetoclax as Pre-emptive Therapy Strategy for MRD+ AML: a Prospective, Single-arm, Multicenter Clinical StudyNot yet recruitingNCT07264010Phase 2/3
- Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic DermatitisRecruitingNCT07262983Phase 1
- Trifluridine/Tipiracil Plus Fruquintinib vs. Trifluridine/Tipiracil Plus Bevacizumab in Refractory Metastatic Colorectal Cancer: A Randomized, Controlled, Open-Label, Non-Inferiority TrialNot yet recruitingNCT07261709Phase 2
- Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque PsoriasisRecruitingNCT07261306Early Phase 1
- Obinutuzumab, Zanubrutinib, and Lenalidomide in First-line Treatment of Mantle Cell LymphomaRecruitingNCT07261163Phase 2
- Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction for Inpatients and Outpatients With Acute Severe Ulcerative ColitisRecruitingNCT07258771Phase 4
- Pomalidomide Plus Orelabrutinib and Zuberitamab in Untreated Mantle Cell LymphomaRecruitingNCT07257510Not applicable
- A Clinical Trial of Envafolimab Combined With Lenvatinib for Kidney Cancer With Liver SpreadNot yet recruitingNCT07256223Phase 2
- Pirtobrutinib, Lisaftoclax, and Rituximab in the Treatment of R/R DLBCLRecruitingNCT07255963Phase 2
- Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell DiseaseRecruitingNCT07252050Phase 1/2
- A Trial of SHR0302 Tablets and SHR0302 Base Gel in Patients With Non-segmental VitiligoRecruitingNCT07251595Phase 2
- A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque PsoriasisRecruitingNCT07250802Phase 3
- Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALLRecruitingNCT07250087Phase 1
- Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell TransplantationRecruitingNCT07249346Phase 2
- A Study of Zasocitinib in Adults With Hidradenitis SuppurativaRecruitingNCT07244263Phase 2
- Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down SyndromeRecruitingNCT07242638Phase 2
- Optimization of Post-transplantation Benadamustine and Cyclophosphamide in Patients With High-risk Myeloid Malignancies and a Partially Mismatched DonorRecruitingNCT07238712Phase 2
- A Study to Evaluate Efficacy and Safety of LNK01001 in Adults With Ankylosing SpondylitisRecruitingNCT07237568Phase 3
- Combination of Carilizumab, Apatinib, and Radiotherapy for Advanced Mucosal MelanomaNot yet recruitingNCT07236528Phase 2
- Ensartinib After Chemoradiotherapy in Stage III ALK-Mutated NSCLCNot yet recruitingNCT07235306Phase 2
- A Study to Evaluate Effectiveness and Safety of a TYK2 Inhibitor in Subjects With Moderate to Severe Plaque PsoriasisRecruitingNCT07234591Not applicable
- A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19)RecruitingNCT07234162Phase 3
- A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)RecruitingNCT07231952Phase 2
- A Phase II Clinical Study of Aipalolitovorelizumab (QL1706) Combined With Fruquintinib in the Treatment of Immunodominant pMMR/MSS Metastatic Colorectal Cancer That Has Failed Second-line or Above TreatmentNot yet recruitingNCT07229872Phase 2
- Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung CancerNot yet recruitingNCT07229339Phase 2
- Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap SyndromesRecruitingNCT07228624Phase 2
- A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)RecruitingNCT07227402Phase 3
- Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling InhibitorsRecruitingNCT07226713Phase 2
- Maintenance Zanzalintinib and Durvalumab in Participants With Advanced Hepatocellular CancerNot yet recruitingNCT07226063Phase 2
- A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple SclerosisRecruitingNCT07225504Phase 3
- Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/LymphomaRecruitingNCT07224100Phase 2
- A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MSNot yet recruitingNCT07222956Phase 2
- A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)RecruitingNCT07222332Phase 3
- A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and AdultsRecruitingNCT07222137Phase 3
- Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID TrialRecruitingNCT07220187Phase 3
- A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.RecruitingNCT07219615Phase 2
- Retifanlimab and Ruxolitinib In Solid MalignanciesRecruitingNCT07219576Phase 1/2
- A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib TherapyRecruitingNCT07218926Phase 3
- Zanzalintinib in Men With Aggressive Variant Prostate CancerRecruitingNCT07218666Phase 2
- A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary TractRecruitingNCT07218380Phase 3
- A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaRecruitingNCT07218341Phase 4
- Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaRecruitingNCT07213973Phase 2
- STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal CancerRecruitingNCT07213570Phase 2
- Baricitinib Curative Repression of HIV-1Not yet recruitingNCT07209267Phase 2
- Combination Therapy With Tazemetostat in Relapsed and Refractory Peripheral T-cell LymphomaNot yet recruitingNCT07209163Phase 1/2
- Orelabrutinib Combined With Zebetuzumab and Lenalidomide for the Treatment of Newly Diagnosed MZLRecruitingNCT07208981Phase 2
- PirtobrUtinib as Frontline Therapy for Elderly Unfit/Frail Patient With MAntle Cell LymphomaNot yet recruitingNCT07207785Phase 2
- A Study to Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLCRecruitingNCT07206498Phase 1/2
- Chemotherapy Combined With Targeted Therapy as First-line Treatment for Mantle Cell Lymphoma Based on MRD and PET-CT AssessmentNot yet recruitingNCT07206264Phase 2
- A Multicenter, Single-arm, Prospective Phase II Clinical Study of Epalrotokewali Combined With Eribulin, Anlotinib, and Radiotherapy for the Treatment of Patients With Advanced Soft Tissue Sarcoma.Not yet recruitingNCT07205185Phase 2
- The Role of Janus Kinase (JAK) and Voltage-gated Sodium Channels (Nav) on Pain and ItchNot yet recruitingNCT07203274Not applicable
- Orelabrutinib and Rituximab With Optional Autologous Hematopoietic Stem Cell Transplantation in MCL TreatmentRecruitingNCT07199296Phase 2
- An Exploratory Study of Golidocitinib in Adult Patients With ITPNot yet recruitingNCT07196163Phase 1/2
- Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD MutationsRecruitingNCT07195695Phase 3
- Nemtabrutinib and Lisocabtagene Maraleucel for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaRecruitingNCT07194980Phase 2
- Metastatic Ewing's Trial Testing Schedule Enhancement to Improve OutcomesRecruitingNCT07194044Phase 1