Tolcapone: all 26 studies that test it
Page 1 of 1. Open to participants first (1), then studies with results posted, then the rest; newest registration first within each.
- Evaluation of Tolcapone as a Cognitive Enhancer in SchizophreniaRecruitingNCT06387771Phase 2
- A Clinical Trial of Tolcapone in Obsessive Compulsive DisorderCompletedNCT05624528Phase 2Results posted
- Tolcapone in Obsessive Compulsive DisorderCompletedNCT03348930Phase 2/3Results posted
- Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive ControlCompletedNCT02949934Phase 2Results posted
- Dopamine Responsivity in GamblersCompletedNCT02772978Not applicableResults posted
- Effects of Tolcapone on Decision Making and Alcohol Intake in Alcohol UsersCompletedNCT02740582Phase 2Results posted
- Remediation of Impaired Self-Regulation in Patients With Mild TBICompletedNCT02260570Early Phase 1Results posted
- Pilot Study of Tolcapone in SmokersCompletedNCT01202955Phase 2Results posted
- A Study of Neural Circuit Responses to Catechol-O-methyl Transferase (COMT) InhibitorsCompletedNCT01158950Not applicableResults posted
- Neural Substrates in Nicotine WithdrawalCompletedNCT01001520Phase 2Results posted
- Tolcapone Treatment of Pathological GamblingCompletedNCT00927563Phase 2Results posted
- Effects of Tolcapone on Frontotemporal DementiaCompletedNCT00604591Phase 2Results posted
- Clinical Trial of Tolcapone for Cognition in SchizophreniaTerminatedNCT00044083Phase 2Results posted
- Microbiome Derived Metabolism and PharmacokineticsCompletedNCT05065671Phase 1
- Dopaminergic Mechanisms Underlying Human Social BehaviorCompletedNCT04205994Early Phase 1
- COMT Inhibition Among Individuals With Comorbid AUD/ADHDCompletedNCT03904498Phase 2
- A Study Assessing the Safety and Pharmacokinetic Profile of Modified Release Formulations of TolcaponeCompletedNCT03633591Phase 1
- Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)CompletedNCT03591757Early Phase 1
- A Trial Evaluating Effects of COMT Inhibition in Patients With Acquired Brain InjuryStatus unknownNCT03273062Phase 2
- Dopaminergic Modulation of Frontostriatal Function With a Dopamine Agonist and COMT InhibitorWithdrawnNCT02929485Phase 4
- Evaluate the Effects of Tolcapone on Cognitive and Behavioral Dysfunction in Patients With BI and NCDStatus unknownNCT02652598Phase 2
- Trial of Tolcapone With Oxaliplatin for NeuroblastomaTerminatedNCT02630043Phase 1
- Study of SOM0226 in Familial Amyloid PolyneuropathyCompletedNCT02191826Phase 1/2
- Role of the Catechol-O-methyltransferase (COMT) in the Physiological Regulation of VigilanceCompletedNCT02080715Phase 1
- Pharmacokinetics of Levodopa/Carbidopa Infusion With and Without Oral Catechol-O-methyl Transferase (COMT) InhibitorsCompletedNCT00906828Phase 4
- Assessment of Potential Interactions Between Cocaine and Tolcapone - 1Status unknownNCT00033059Phase 1