Tiotropium: all 166 studies that test it

Page 1 of 2. Open to participants first (2), then studies with results posted, then the rest; newest registration first within each.

• PREterm Infants With Bronchial Obstruction - Prospective Study of Efficacy and Safety of Inhaled TiotropiumNot yet recruitingNCT07827859Phase 4
• Evaluating the Impact of Single Dose Tiotropium on Allergen-induced Early Asthmatic ResponseNot yet recruitingNCT06679465Phase 4
• A Study to Test the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler in People With Chronic Obstructive Pulmonary Disease (COPD) Who Have Different Abilities to InhaleCompletedNCT04223843Phase 4Results posted
• A Comparative Study Between Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy Versus Tiotropium Monotherapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03474081Phase 4Results posted
• The ENERGITO® 2 Study Compares 2 Inhaled Medicines for Chronic Obstructive Pulmonary Disease (COPD). One Medicine is a Combination of Tiotropium and Olodaterol (Stiolto®) Taken Using the Respimat® Inhaler and the Other Medicine is a Combination of Fluticasone and Salmeterol Taken Using the DiskusCompletedNCT03240575Phase 4Results posted
• Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)TerminatedNCT03219866Phase 4Results posted
• Efficacy of Intermittent Tiotropium in Early Childhood WheezingTerminatedNCT03199976Phase 4Results posted
• Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03118765Phase 2Results posted
• Cardiovascular Function in COPD PatientsCompletedNCT03055988Phase 4Results posted
• The Effects of RPL554 in Addition to Tiotropium in COPD PatientsCompletedNCT03028142Phase 2Results posted
• Bioavailability of Tiotropium + Olodaterol Fixed-dose Combination (5 μg/ 5 μg) in Chinese COPD PatientsCompletedNCT02969317Phase 1Results posted
• AMPLIFY - D6571C00001 Duaklir USA Phase III StudyCompletedNCT02796677Phase 3Results posted
• Pharmacokinetics and Safety of BI 1744 CL Plus Tiotropium Bromide in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02231177Phase 1Results posted
• Lung Function and Patient Preference With QVA149 vs. Tiotropium in COPD PatientsCompletedNCT02125734Phase 4Results posted
• To Evaluate the Effect of Inhaled Medication Together With Exercise and Activity Training on Exercise Capacity and Daily Activities in Patients With Chronic Lung Disease With Obstruction of AirwaysCompletedNCT02085161Phase 3Results posted
• Study to Evaluate the Effect on Lung Function and ECG When a Combination of Tiotropium Plus Olodaterol is Administered to Patients With COPD Either From a Single Inhaler or Each Compound is Administered After Each Other From Two Different InhalersCompletedNCT02030535Phase 2Results posted
• Tiotropium+Olodaterol Fixed Dose Combination (FDC) in Chronic Obstructive Pulmonary Disease (OTEMTO 2)CompletedNCT02006732Phase 3Results posted
• Characterization of Lung Function Profile of Inhaled Tiotropium + Olodaterol Fixed Dose Combination Compared to Fluticasone Propionate + Salmeterol Fixed Dose Combination in COPD PatientsCompletedNCT01969721Phase 3Results posted
• Tiotropium + Olodaterol Fixed Dose Combination (FDC) in Chronic Obstructive Pulmonary Disease (OTEMTO 1)CompletedNCT01964352Phase 3Results posted
• Effect of Glycopyrronium on Morning Symptoms and Pulmonary Function in Patients With Moderate to Severe COPDCompletedNCT01959516Phase 4Results posted
• Efficacy of NVA237 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01922271Phase 4Results posted
• A 1-year Multi-center, Prospective, Cohort Study in Patients With Chronic Obstructive Pulmonary Disease Treated With Long-acting BronchodilatorCompletedNCT01794780Phase 4Results posted
• Evaluating the Control of COPD Symptoms in Patients Treated With Tiotropium Bromide 18mcg Once Daily Alone, ADOAIR 50/250mcg Twice Daily Alone or ADOAIR 50/250mcg Plus Tiotropium Bromide 18mcgCompletedNCT01762800Phase 4Results posted
• A 3 Way Cross-over Study Evaluating the Effects of ADOAIR Twice Daily Plus Tiotropium Bromide Once Daily Compared With the Individual Treatments of Japanese SubjectsCompletedNCT01751113Phase 4Results posted
• A Study to Characterize Pharmacokinetics of Tiotropium + Olodaterol Fixed-dose Combination in Japanese Patients With COPD.CompletedNCT01703845Phase 1Results posted
• Comparison of Two Daily Dose Regimens of Tiotropium 5 µg Once Daily and Tiotropium 2.5 µg Twice Daily for 4 Weeks on Top of Maintenance Therapy With Inhaled Corticosteroid Controller MedicationCompletedNCT01696071Phase 2Results posted
• Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 1CompletedNCT01663987Phase 4Results posted
• Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 2CompletedNCT01662986Phase 4Results posted
• Assessment of Health-status of Patients With Chronic Obstructive Pulmonary Disease (COPD) on Maintenance Therapy With Spiriva HH Measured by COPD Assessment Test (CAT) TestCompletedNCT01644734Phase 4Results posted
• Evaluation of Tiotropium 2.5 and 5 mcg Once Daily Delivered Via the Respimat® Inhaler Compared to Placebo in 1 to 5 Year Old Patients With Persistent AsthmaCompletedNCT01634113Phase 2Results posted
• Characterization of 24-hour Lung Function Profiles of Inhaled Tiotropium + Olodaterol Fixed Dose Combination in Patients Suffering From Chronic Obstructive Pulmonary DiseaseCompletedNCT01559116Phase 3Results posted
• Japan Long-term Safety for Tiotropium Plus OlodaterolCompletedNCT01536262Phase 3Results posted
• Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients.CompletedNCT01533935Phase 3Results posted
• Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD PatientsCompletedNCT01533922Phase 3Results posted
• A Study to Determine the Effect of Tiotropium + Olodaterol Fixed Dose Combination on Exercise Endurance Time During Constant Work Rate Cycle Ergometry Test in COPDCompletedNCT01525615Phase 3Results posted
• Tiotropium (18mcg) in Chronic Obstructive Pulmonary Disease (COPD) Patients With a Respiratory InfectionCompletedNCT01483625Phase 4Results posted
• Tiotropium +Olodaterol Fixed Dose Combination (FDC) Versus Tiotropium and Olodaterol in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01431287Phase 3Results posted
• Tiotropium+Olodaterol Fixed Dose Combination (FDC) Versus Tiotropium and Olodaterol in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01431274Phase 3Results posted
• A Study to Evaluate Efficacy and Safety of Tiotropium in Children 6 to 11 Years Old With Moderate AsthmaCompletedNCT01383499Phase 2Results posted
• Efficacy and Safety of 2 Doses of Tiotropium Via Respimat in Adult Patients With Mild Persistent AsthmaCompletedNCT01316380Phase 3Results posted
• Blacks and Exacerbations on Long Acting Beta Agonists (LABA) vs. Tiotropium (BELT)CompletedNCT01290874Phase 3Results posted
• Randomised, Double- Blind, Cross-over Efficacy and Safety Comparison of Three Different Doses of Tiotropium Administered Once Daily Versus Placebo in Patients With Moderate Persistent Asthma.CompletedNCT01233284Phase 2Results posted
• A Randomised, Double- Blind, Placebo Controlled, Cross-over Efficacy and Safety Comparison of Tiotropium 5 µg Once Daily and Tiotropium 2.5 µg Twice Daily for Four Weeks in Patients With Moderate Persistent AsthmaCompletedNCT01152450Phase 2Results posted
• Comparison of Tiotropium in the HandiHaler Versus the Respimat in Chronic Obstructive Pulmonary DiseaseCompletedNCT01126437Phase 3Results posted
• Efficacy and Safety of 3 Doses of Tiotropium Compared to Placebo in Adolescents (12 to 17 Yrs) With Moderate AsthmaCompletedNCT01122680Phase 2Results posted
• Long Term Safety and Tolerability of NVA237 Versus Tiotropium in Japanese PatientsCompletedNCT01119937Phase 3Results posted
• Bronchodilator Responsiveness in Obliterative BronchiolitisCompletedNCT01112241Phase 4Results posted
• Effects of Tiotropium on Breathing Capacity and Exercise Limitation in Early Stages of Chronic Obstructive Pulmonary DiseaseCompletedNCT01072396Phase 4Results posted
• Effect of Indacaterol on Inspiratory Capacity (IC)CompletedNCT01012765Phase 3Results posted
• Comparison of the Effects of Indacaterol and Tiotropium on Inspiratory CapacityCompletedNCT00999908Phase 3Results posted
• The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT00870896Early Phase 1Results posted
• Evaluation of Tiotropium 5 µg/Day Delivered Via the Respimat® Inhaler Over 48 Weeks in Patients With Severe Persistent Asthma on Top of Usual Care (Study II)CompletedNCT00776984Phase 3Results posted
• Evaluation of Tiotropium 5 µg/Day Delivered Via the Respimat® Inhaler Over 48 Weeks in Patients With Severe Persistent Asthma on Top of Usual Care (Study I)CompletedNCT00772538Phase 3Results posted
• Safety and Efficacy of 12-wk Treatment With Two Doses of Tiotropium Respimat in Cystic FibrosisCompletedNCT00737100Phase 2Results posted
• Efficacy and Safety of 4 Weeks of Treatment With Orally Inhaled BI1744/Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT00720499Phase 2Results posted
• The Effects of Different Long-acting Bronchodilator Medications on Asthma Patients With Different Genetic VariationsTerminatedNCT00706446Not applicableResults posted
• Combination of Orally Inhaled BI1744CL/Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease ( COPD)CompletedNCT00696020Phase 2Results posted
• Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease PatientsCompletedNCT00680056Phase 4Results posted
• Tiotropium/Salmeterol Inhalation Powder in COPDTerminatedNCT00668772Phase 3Results posted
• Efficacy and Safety Comparison of Tiotropium Daily + Salmeterol Daily or Twice Daily Versus Tiotropium Daily in Patients With COPDCompletedNCT00662792Phase 3Results posted
• A Crossover Study to Determine the Effect on Lung Function of Indacaterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Using Tiotropium as an Active ControlCompletedNCT00615459Phase 3Results posted
• Cardiac Limitations in Chronic Obstructive Pulmonary Disease: Benefits of BronchodilationCompletedNCT00578968Phase 4Results posted
• Asthma Clinical Research Network (ACRN) Trial - Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC)CompletedNCT00565266Phase 3Results posted
• Tiotropium Once Daily 18 Mcg Versus Salmeterol Twice Daily 50 Mcg on Time to First Exacerbation in COPD Patients.CompletedNCT00563381Phase 4Results posted
• Effect of Tiotropium Plus Salmeterol vs. Fluticasone/Salmeterol on Static Lung Volumes and Exercise Endurance in COPDCompletedNCT00530842Phase 4Results posted
• An Efficacy and Safety Study to Compare Three Doses of BEA 2180 BR to Tiotropium and Placebo in the Respimat Inhaler.CompletedNCT00528996Phase 2Results posted
• Tiotropium In ExerciseCompletedNCT00525512Phase 4Results posted
• Trial Comparing Tiotropium Inhalation Capsules vs Placebo in Chronic Obstructive Pulmonary Disease (COPD).CompletedNCT00523991Phase 4Results posted
• Safety Study Using GSK573719 And Tiotropium In Patients With Chronic Obstructive Pulmonary DiseaseCompletedNCT00515502Phase 2Results posted
• Evaluation of Efficacy and Safety of Symbicort® as an add-on Treatment to Spiriva® in Patients With Severe COPD.CompletedNCT00496470Phase 4Results posted
• Efficacy Safety Study of Arformoterol/Tiotropium Combination Versus Either Therapy Alone in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT00424528Phase 4Results posted
• Tiotropium / Respimat One Year Study in COPD.CompletedNCT00387088Phase 3Results posted
• A Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent Inhalation Aerosol in COPD Patients.CompletedNCT00359788Phase 4Results posted
• Efficacy and Safety of Tiotropium and Salmeterol in Moderate Persistent Asthma Patients Homozygous for B16-Arg/ArgCompletedNCT00350207Phase 2Results posted
• Evaluation of the Long- Term Effects of Spiriva on Lung Function in COPD PatientsCompletedNCT00144339Phase 3Results posted
• Comparative Efficacy of Once-daily LAMA/LABA Combinations Versus Tiotropium on Constant-work-rate Cycle Endurance in COPDSuspendedNCT07541378Not applicable
• Open Label Study to Assess the Effect of Patient Use and Robustness of Tiotropium 18ug Inhalation Powder, Hard Capsule,Zephir Inhaler DeviceCompletedNCT06254664Phase 1
• Effects of Acute Long-acting Bronchodilation on Oxygenation and Peripheral Ventilation in COPDCompletedNCT05927155Phase 3
• Tiotropium Handihaler vs. Tiotropium Respimat in COPDWithdrawnNCT05838703Phase 2
• Comparison of Tiotropium Absorption From Tiotropium Easyhaler and Spiriva HandiHalerCompletedNCT05246046Phase 1
• Regular Use Tiotropium and Tolerance to Bronchoprotection in Mild AsthmaCompletedNCT05113615Phase 4
• Effects of Tiotropium/Olodaterol on Cardio-pulmonary Exercise Capacity in Patients With Hyperinflated Chronic Obstructive Pulmonary Disease [ACHIEVE]CompletedNCT04994574Not applicable
• Tiotropium vs. Inhaled Corticosteroids in Children With Nonatopic Asthma Pilot Study (TioNAAP)TerminatedNCT04990167Phase 2
• Tiotropium Efficacy Against Allergen Induced Early Asthmatic ResponsesCompletedNCT04648813Phase 4
• Three Treatment of Chronic Obstructive Pulmonary Disease PatientsCompletedNCT04520230Phase 4
• Methacholine, Long-acting M-cholinolytic and beta2-agonist on the Activity of Beta-receptors in Healthy VolunteersStatus unknownNCT04137029Not applicable
• Anti-inflammatory Effects of Tiotropium in Patients with Stable COPDCompletedNCT04061161Phase 4
• Effect of Charcoal on Gastrointestinal Absorption of TiotropiumCompletedNCT03945344Phase 1
• Effect of Tiotropium on Airway Remodeling in Patients With Early Stage COPD Accessed by Optical Coherence TomographyCompletedNCT03842839Not applicable
• Effects of Dual Bronchodilator Treatment on Cardiopulmonary Interactions in COPDCompletedNCT03425617Phase 4
• Pharmacokinetic Study Comparing Tiotropium Easyhaler and Spiriva HandihalerCompletedNCT03400241Phase 1
• Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With ReferenceCompletedNCT03302065Phase 1
• Efficiency of Twice Daily Formoterol Versus Once Daily Tiotropium in Patients With GOLD A/B COPDStatus unknownNCT03258749Not applicable
• Two-period 21 Day Cross-over Study to Compare the Pharmacokinetics of Tiotropium From Two InhalersCompletedNCT03246581Phase 1
• Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With A Reference ProductCompletedNCT03155204Early Phase 1
• INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and OlodaterolCompletedNCT03152149Phase 4
• Tiotropium/Formoterol Via Discair® vs Tiotropium Monotherapy or Tiotropium + Formoterol Free Combination TreatmentCompletedNCT02988869Phase 4
• Effects of Long Acting Bronchodilators on CARDiac Autonomic Control in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02872090Phase 4
• Cross-over Study in Volunteers to Compare the Pharmacokinetics of Tiotropium Delivered From Test and Reference ProductsCompletedNCT02676297Phase 1
• Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With Two Reference ProductsCompletedNCT02627625Phase 1

← Tiotropium overview