Drug
Tacabrutideg clinical trials
Also written BGB-16673.
- studies test it
- 10
- open now
- 9
- in phase 3
- 2
- first study started
- 2021
Keep track of what changes. Save the tacabrutideg studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
9 studies that test it; most in 2025 (5); 1 more planned to start later
| Year | Studies |
|---|---|
| 2021 | 1 |
| 2022 | 1 |
| 2025 | 5 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 5
- Phase 3
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 7 · Other 3
BeOne Medicines (6) · BeiGene (1) · Fred Hutchinson Cancer Center (1) · M.D. Anderson Cancer Center (1) · Massachusetts General Hospital (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses tacabrutideg is read from its arms, and is right about nine times in ten.
Testing it · 10
- Tacabrutideg and Sonrotoclax, With Response-Guided Obinutuzumab, for the Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)Not yet recruitingPhase 2Fred Hutchinson Cancer CenterNCT07887061Written as Tacabrutideg
- Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-DegraderRecruitingPhase 1/2BeOne MedicinesNCT05294731Written as Tacabrutideg
- A Phase 2 Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With BCL-2 Inhibitor Sonrotoclax For Patients With Treatment-Naive Chronic Lymphocytic Leukemia (CLL)RecruitingPhase 2M.D. Anderson Cancer CenterNCT07508995Written as BGB-16673
- A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell MalignanciesRecruitingPhase 1/2BeOne MedicinesNCT05006716Written as Tacabrutideg
- A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Tacabrutideg (BGB-16673) in Participants With Moderate and Severe Hepatic ImpairmentNot yet recruitingPhase 1BeOne MedicinesNCT07856004Written as Tacabrutideg
- A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaRecruitingPhase 3BeOne MedicinesNCT06973187Written as Tacabrutideg
- A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) InhibitorsRecruitingPhase 3BeOne MedicinesNCT06846671Written as Tacabrutideg
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple-Ascending Doses of Tacabrutideg (BGB-16673) in Adults With Chronic Spontaneous Urticaria and in Healthy ParticipantsRecruitingPhase 1BeOne MedicinesNCT07005713Written as Tacabrutideg
- Zanubrutinib, Obinutuzumab, Sonrotoclax (BOSon) or BGB-16673, Obinutuzumab, Sonrotoclax (DOSon) in TN CLL/SLLRecruitingPhase 2Massachusetts General HospitalNCT06849713Written as Tacabrutideg
- A Study of How [14C]-BGB-16673 is Absorbed, Broken Down, and Removed From the Body After a Single Oral Dose in Healthy ParticipantsCompletedPhase 1BeiGeneNCT06776679Written as [14C]-BGB-16673
Given in every arm · 3 — tacabrutideg is usual care beside what is tested
- A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell MalignanciesRecruitingPhase 1/2BeOne MedicinesNCT06634589Written as Tacabrutideg
- A Study of BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) InhibitorsActive, not recruitingPhase 3BeOne MedicinesNCT06970743Written as BGB-16673
- Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy ParticipantsCompletedPhase 1BeiGeneNCT06906809Written as BGB-16673
Codes
What other systems call tacabrutideg · ClinicalTrials.gg INT017577
- UNII (FDA) PF6GPZ4DYTTACABRUTIDEGOne source FDA
- NCI Thesaurus C215275TacabrutidegOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | PF6GPZ4DYT | TACABRUTIDEG | One source FDA |
| NCI Thesaurus | C215275 | Tacabrutideg | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.