Squaric acid dibutyl ester clinical trials
How each study uses squaric acid dibutyl ester is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
4 studies that test it; most in 2016 (1); 1 more planned to start later
| Year | Studies |
|---|---|
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2022 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 3 · Other 2
Squarex, LLC (3) · Massachusetts General Hospital (1) · The University of Texas Health Science Center, Houston (1)
Studies
Open first, then newest update. How each study uses squaric acid dibutyl ester is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 5
- SADBE for Congenital Melanocytic NeviNot yet recruitingEarly Phase 1Massachusetts General HospitalNCT04999631Written as Squaric Acid Dibutyl Ester
- Study Evaluating Efficacy of Topical Squaric Acid Dibutyl Ester in Children and Adolescents With Alopecia AreataStatus unknownEarly Phase 1The University of Texas Health Science Center, HoustonNCT05414266Written as SADBE 5%
- Immune Response and General Immune Health in Subjects Infected With Herpes Simplex Virus Type 1 (HSV-1)CompletedPhase 1Squarex, LLCNCT03661541Written as Squaric Acid Dibutyl Ester
- Double-blind, Vehicle-controlled Study of the Efficacy and Safety of SADBE in Subjects With Recurrent Herpes LabialisCompletedPhase 1/2Squarex, LLCNCT02965781Written as SADBE
- A Phase 2, Muti-Center Study of Repeat Dosing of Squaric Acid Dibutyl Ester in Subjects With Herpes LabialisTerminatedPhase 2Squarex, LLCNCT03521479Written as Squaric Acid Dibutyl Ester
Given beside what is tested · 1 — squaric acid dibutyl ester is usual care or a partner of the new treatment
Codes
What other systems call squaric acid dibutyl ester · ClinicalTrials.gg INT002727
- MeSH (NLM) C020637squaric acid dibutyl esterConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 4RTO57VG65DIBUTYL SQUARATEConfirmed NLM, Wikidata
- Wikidata Q26841197squaric acid dibutyl esterConfirmed NLM, Wikidata
- DrugBank DB12223One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C020637 | squaric acid dibutyl ester | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 4RTO57VG65 | DIBUTYL SQUARATE | Confirmed NLM, Wikidata |
| Wikidata | Q26841197 | squaric acid dibutyl ester | Confirmed NLM, Wikidata |
| DrugBank | DB12223 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.