Sorafenib: all 509 studies that test it

Page 1 of 6. Open to participants first (13), then studies with results posted, then the rest; newest registration first within each.

• Sorafenib Combined With Venetoclax as Pre-emptive Therapy Strategy for MRD+ AML: a Prospective, Single-arm, Multicenter Clinical StudyNot yet recruitingNCT07264010Phase 2/3
• Molecular Genetics Guide the Maintenance Therapy After Allogeneic Hematopoietic Stem Cell TransplantationRecruitingNCT06972641Phase 2/3
• Sorafenib Relapase Prophylaxis After HCT With PTBCy RegimenRecruitingNCT06532084Phase 2
• Clinical Pharmacogenetic Study of Sorafenib in Egyptian Patients With Hepatocellular CarcinomaRecruitingNCT06527495Phase 1/2
• Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid CancerRecruitingNCT06482086Phase 2
• Phase 2 Study of WGI-0301 for Advanced HCCRecruitingNCT06309485Phase 2
• Efficacy and Safety of Sorafenib in New-Onset Type 1 Diabetes MellitusNot yet recruitingNCT06227221Phase 2
• AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular CarcinomaRecruitingNCT05669339Phase 2
• SNF Platform Study of HR+/ HER2-advanced Breast CancerRecruitingNCT05594095Phase 2
• Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor PatientsRecruitingNCT05468359Phase 1/2
• Treateament of Newly Diagnosed Acute Monocytic Leukemia in ChildrenRecruitingNCT05313958Phase 2/3
• Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBsAg+ Advanced Stage HCCRecruitingNCT03899428Phase 2
• Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatmentRecruitingNCT02029001Phase 2
• Phase II Trial of Vemurafenib and Sorafenib in Pancreatic CancerCompletedNCT05068752Phase 2Results posted
• AflacLL1901 (CHOA-AML)TerminatedNCT04326439Phase 2Results posted
• Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid CancerTerminatedNCT03630120Phase 2Results posted
• Study to Assess the Long-term Safety of Lenvatinib Monotherapy, a Lenvatinib Combination Regimen, or a Comparator Treatment Arm to Cancer Participants in Eisai Sponsored Lenvatinib TrialsCompletedNCT03477175Phase 2Results posted
• Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver CancerCompletedNCT03439891Phase 2Results posted
• Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver CancerCompletedNCT03211416Phase 1/2Results posted
• Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular CancerCompletedNCT03037437Phase 2Results posted
• Filgrastim, Cladribine, Cytarabine, and Mitoxantrone With Sorafenib in Treating Patients With Newly-Diagnosed, Acute Myeloid Leukemia or High-Risk Myelodysplastic SyndromeCompletedNCT02728050Phase 1/2Results posted
• 2nd Line Treatment With Pemetrexed and Sorafenib for Recurrent or Metastatic Triple Negative Breast CancerTerminatedNCT02624700Phase 2Results posted
• Trial of TRC105 and Sorafenib in Patients With HCCCompletedNCT02560779Phase 1/2Results posted
• Personalized Targeted Inhibitors Treatment in Renal Cell CancerTerminatedNCT02560012Phase 2Results posted
• Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid LeukemiaCompletedNCT02530476Phase 1/2Results posted
• Sorafenib Plus 5-Azacitidine Initial Therapy of Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MS) With FLT3-ITD MutationCompletedNCT02196857Phase 2Results posted
• A Study of LY2157299 in Participants With Advanced Hepatocellular CarcinomaCompletedNCT02178358Phase 2Results posted
• Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive FibromatosisCompletedNCT02066181Phase 3Results posted
• Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue SarcomaCompletedNCT02050919Phase 2Results posted
• Study of Dalantercept and Sorafenib in Patients With Advanced Hepatocellular CarcinomaCompletedNCT02024087Phase 1/2Results posted
• Sorafenib for Hepatopulmonary SyndromeTerminatedNCT02021929Phase 2Results posted
• Efficacy, Safety, and Pharmacokinetic of MSC2156119J in Asian Participants With Hepatocellular CarcinomaCompletedNCT01988493Phase 1/2Results posted
• Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell TumorsCompletedNCT01946529Phase 2Results posted
• Sorafenib Tosylate and Yttrium Y 90 Glass Microspheres in Treating Patients With Liver Cancer That Cannot Be Removed by SurgeryCompletedNCT01900002Phase 2Results posted
• HCV-RNA Kinetics During Sorafenib for Hepatocellular Carcinoma (HCC)TerminatedNCT01849588Phase 4Results posted
• Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade GliomaCompletedNCT01817751Phase 2Results posted
• Sorafenib + mFOLFOX for Hepatocellular CarcinomaCompletedNCT01775501Phase 2Results posted
• A Multicenter, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib (E7080) Versus Sorafenib in First-line Treatment of Participants With Unresectable Hepatocellular CarcinomaCompletedNCT01761266Phase 3Results posted
• A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and EffectiveCompletedNCT01754987Phase 1/2Results posted
• The Effect of Sorafenib on Portal PressureCompletedNCT01714609Phase 2Results posted
• Trebananib With or Without Bevacizumab, Pazopanib Hydrochloride, Sorafenib Tosylate, or Sunitinib Malate in Treating Patients With Advanced Kidney CancerCompletedNCT01664182Phase 2Results posted
• Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous LeukemiaTerminatedNCT01620216Phase 2Results posted
• A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-Cell Lymphoma PatientsCompletedNCT01561833Phase 1Results posted
• Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib for the Treatment of Acute Myeloid Leukemia With Complex- or Poor-risk (Monosomy 5/7) Cytogenetics or FLT3-ITD Positive GenotypeCompletedNCT01534260Phase 1/2Results posted
• Sorafenib for the Treatment of Chronic Lymphocytic Leukemia (CLL)TerminatedNCT01510756Phase 2Results posted
• Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid CancerCompletedNCT01502410Phase 2Results posted
• Sorafenib Plus Capecitabine (SorCape) in Previously Treated Metastatic Colorectal CancerCompletedNCT01471353Phase 2Results posted
• Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or LeukemiaCompletedNCT01445080Phase 1/2Results posted
• Phase I-II Everolimus and Sorafenib in Recurrent High-Grade GliomasCompletedNCT01434602Phase 1/2Results posted
• Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01371981Phase 3Results posted
• Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade AstrocytomasTerminatedNCT01338857Phase 2Results posted
• A Phase II Trial of OSI-906 and Sorafenib in Advanced Hepatocellular CancerTerminatedNCT01334710Phase 2Results posted
• Sorafenib and TRC105 in Hepatocellular CancerCompletedNCT01306058Phase 1/2Results posted
• E7050 in Combination With Sorafenib Versus Sorafenib Alone as First Line Therapy in Participants With Hepatocellular CarcinomaCompletedNCT01271504Phase 1/2Results posted
• Chemoprevention of Prostate Cancer, HDAC Inhibition and DNA MethylationCompletedNCT01265953Not applicableResults posted
• Study of Bavituximab and Sorafenib In Patients With Advanced Liver CancerCompletedNCT01264705Phase 1/2Results posted
• Sorafenib and 5-Azacitidine in Acute Leukemia + Myelodysplastic SyndromeCompletedNCT01254890Phase 1/2Results posted
• Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid LeukemiaCompletedNCT01253070Phase 2Results posted
• BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung CancerCompletedNCT01248247Phase 2Results posted
• Phase III Trial Comparing Capecitabine in Combination With Sorafenib or Placebo in the Treatment of Locally Advanced or Metastatic HER2-Negative Breast CancerCompletedNCT01234337Phase 3Results posted
• A Study of Dovitinib Versus Sorafenib in Adult Patients With Hepatocellular Carcinoma (HCC) as a First Line TreatmentCompletedNCT01232296Phase 2Results posted
• Preoperative Trial of Sorafenib in Combination With Cisplatin Followed by Paclitaxel for Early Stage Breast CancerTerminatedNCT01194869Phase 2Results posted
• Evaluate Safety and Tolerability in Dose Escalation of Sorafenib in Advanced Renal Cell CancerCompletedNCT01189370Phase 2Results posted
• A Study of Pexa-Vec (JX-594) Prior to Sorafenib to Treat Unresectable Primary Hepatocellular CarcinomaCompletedNCT01171651Phase 2Results posted
• Velcade and Sorafenib in Unresected or Metastatic Renal Cell CarcinomaTerminatedNCT01100242Phase 2Results posted
• Sorafenib Tosylate and Erlotinib Hydrochloride in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gallbladder Cancer or CholangiocarcinomaCompletedNCT01093222Phase 2Results posted
• An Extension Treatment Protocol for Subjects Who Have Participated in a Study of Tivozanib Versus Sorafenib in Kidney Carcinoma (Protocol AV-951-09-301).CompletedNCT01076010Phase 3Results posted
• Sorafenib With Capecitabine for Patients With Measurable Hepatocellular CarcinomaTerminatedNCT01032850Phase 2Results posted
• Combination of Temsirolimus and Sorafenib in the Treatment of Radioactive Iodine Refractory Thyroid CancerCompletedNCT01025453Phase 2Results posted
• Stereotactic Radiation Therapy and Sorafenib in the Treatment of Hepatocellular CarcinomaTerminatedNCT01005875Not applicableResults posted
• Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by SurgeryCompletedNCT01004978Phase 3Results posted
• Nexavar® Versus Placebo in Locally Advanced/Metastatic RAI-Refractory Differentiated Thyroid CancerCompletedNCT00984282Phase 3Results posted
• Depocyt® With Sorafenib in Neoplastic MeningitisTerminatedNCT00964743Not applicableResults posted
• A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract CancerTerminatedNCT00955721Phase 1/2Results posted
• Study to Determine the Safety, Maximum Tolerated Dose, Pharmacokinetics of Sorafenib (BAY43-9006)CompletedNCT00941863Phase 1Results posted
• Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent CetuximabCompletedNCT00939627Phase 2Results posted
• Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate CancerTerminatedNCT00924807Phase 1/2Results posted
• Gemcitabine and Cisplatin Plus Sorafenib in Patients With Advanced Biliary Tract Carcinomas Naive to Systemic TherapyCompletedNCT00919061Phase 2Results posted
• Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by SurgeryTerminatedNCT00880542Phase 2Results posted
• Cisplatin or Carboplatin and Sorafenib in Treating Patients With Liver Cancer That Cannot Be Removed By SurgeryCompletedNCT00875615Phase 2Results posted
• Sorafenib in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Sunitinib or BevacizumabCompletedNCT00866320Phase 2Results posted
• Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) SubjectsCompletedNCT00865709Phase 2Results posted
• Trial of Neoadjuvant Conformal Radiotherapy Plus Sorafenib for Patients With Soft Tissue Sarcoma of the Extremity and Body WallCompletedNCT00864032Phase 1/2Results posted
• A 3rd/4th Line Placebo-controlled Trial of Sorafenib in Patients With Predominantly Non Squamous Non-Small Cell Lung Cancer (NSCLC).CompletedNCT00863746Phase 3Results posted
• A Phase II Randomized, Double-blind, Placebo-controlled Study of Sorafenib or Placebo in Combination With Transarterial Chemoembolization (TACE) Performed With DC Bead and Doxorubicin for Intermediate Stage Hepatocellular Carcinoma (HCC).CompletedNCT00855218Phase 2Results posted
• Safety and Toxicity Study of Sorafenib in Patients With Kidney CancerCompletedNCT00854620Phase 2Results posted
• Study of Sorafenib and Transarterial Chemoembolization (TACE) to Treat Hepatocellular CarcinomaCompletedNCT00844883Phase 2Results posted
• Sorafenib and Erlotinib in Treating Patients With Pancreatic Cancer That Cannot Be Removed by SurgeryCompletedNCT00837876Phase 2Results posted
• Sorafenib and Dacarbazine in Soft Tissue SarcomaCompletedNCT00837148Phase 2Results posted
• Sorafenib and Vinorelbine in Treating Women With Stage IV Breast CancerCompletedNCT00828074Phase 1/2Results posted
• Sorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal CancerCompletedNCT00826540Phase 2Results posted
• Phase I/II Trial of Sorafenib Plus Ixabepilone in HER2-Negative Metastatic Breast CancerCompletedNCT00825734Phase 1/2Results posted
• Study of Sorafenib/Cetuximab in Head and Neck CancerCompletedNCT00815295Phase 1/2Results posted
• Sorafenib Therapy Prior to Radiofrequency Ablation for Intermediate Sized Hepatocellular CancerCompletedNCT00813293Phase 2Results posted
• Sorafenib in Treating Patients With Advanced Malignant Solid TumorsCompletedNCT00810394Phase 2Results posted
• Study of Low Dose Chemotherapy Plus Sorafenib as Initial Therapy for Patients With Advanced Non-Squamous Cell NSCLCTerminatedNCT00801801Phase 2Results posted
• Comparison of Nexavar/Placebo as Maintenance Therapy for Patients With Advanced Ovarian or Primary Peritoneal CancerCompletedNCT00791778Phase 2Results posted
• A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal CancerTerminatedNCT00779311Phase 1Results posted
• Sorafenib in Treating Non-Smokers or Former Light Smokers With Relapsed or Refractory Stage IIIB or Stage IV Non-Small Cell Lung CancerTerminatedNCT00754923Phase 2Results posted
• Sorafenib in Treating Patients With Locally Advanced or Metastatic Kidney CancerTerminatedNCT00727532Not applicableResults posted

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